{"id":4932,"date":"2024-08-04T16:34:18","date_gmt":"2024-08-04T16:34:18","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=4932"},"modified":"2024-08-04T16:34:18","modified_gmt":"2024-08-04T16:34:18","slug":"plantain-seed","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/gyalogakac-mag\/","title":{"rendered":"Alacsony viszkozit\u00e1s\u00fa poliszacharidok el\u0151\u00e1ll\u00edt\u00e1sa Plantago asiatica-b\u00f3l szulfat\u00e1l\u00e1ssal, valamint szerkezeti jellemz\u00e9s\u00fck \u00e9s antioxid\u00e1ns aktivit\u00e1suk"},"content":{"rendered":"<p>Alacsony viszkozit\u00e1s\u00fa poliszacharidok el\u0151\u00e1ll\u00edt\u00e1sa Plantago asiatica-b\u00f3l szulfat\u00e1l\u00e1ssal, valamint szerkezeti jellemz\u00e9s\u00fck \u00e9s antioxid\u00e1ns aktivit\u00e1suk<br \/>\nA poliszacharidok nagy mennyis\u00e9gben fordulnak el\u0151 \u00e1llatokban, n\u00f6v\u00e9nyekben \u00e9s mikroorganizmusokban, \u00e9s alacsony toxicit\u00e1suk \u00e9s kiv\u00e1l\u00f3 biol\u00f3giai aktivit\u00e1suk miatt sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k \u0151ket az \u00e9lelmiszer- \u00e9s gy\u00f3gyszeriparban. A modern kutat\u00e1sok kimutatt\u00e1k, hogy a poliszacharidok k\u00fcl\u00f6nb\u00f6z\u0151 funkci\u00f3kkal rendelkeznek, mint p\u00e9ld\u00e1ul immunszab\u00e1lyoz\u00e1s, daganatellenes, gyullad\u00e1scs\u00f6kkent\u0151, v\u00edrusellenes, antioxid\u00e1ns, sug\u00e1rz\u00e1sellenes, hipoglik\u00e9mi\u00e1s, lipidcs\u00f6kkent\u0151 \u00e9s m\u00e1jv\u00e9d\u0151. Az ut\u00f3bbi \u00e9vekben k\u00fcl\u00f6nb\u00f6z\u0151 poliszacharid-sz\u00e1rmaz\u00e9kos\u00edt\u00e1si m\u00f3dszereket fejlesztettek ki a poliszacharidok biol\u00f3giai aktivit\u00e1s\u00e1nak fokoz\u00e1s\u00e1ra \u00e9s fizikai-k\u00e9miai tulajdons\u00e1gainak optimaliz\u00e1l\u00e1s\u00e1ra, mint p\u00e9ld\u00e1ul szulfat\u00e1l\u00e1s, acetil\u00e1l\u00e1s, karboximetil\u00e1l\u00e1s \u00e9s foszforil\u00e1l\u00e1s. A poliszacharidok szulfat\u00e1l\u00e1sa jelent\u0151sen jav\u00edthatja szerkezeti jellemz\u0151iket, jav\u00edthatja biol\u00f3giai aktivit\u00e1sukat, s\u0151t \u00faj biol\u00f3giai aktivit\u00e1st is adhat nekik. Yang \u00e9s munkat\u00e1rsai a natto poliszacharidok szulfat\u00e1l\u00e1s\u00e1t vizsg\u00e1lt\u00e1k kl\u00f3rszulf\u00e1t-piridin m\u00f3dszerrel, \u00e9s a szulfat\u00e1lt natto poliszacharidok antibakteri\u00e1lis aktivit\u00e1sa fokoz\u00f3dott. Chen \u00e9s munkat\u00e1rsai kl\u00f3rszulf\u00e1t-piridin m\u00f3dszerrel szulfat\u00e1lt jamgy\u00f6k\u00e9r poliszacharid sz\u00e1rmaz\u00e9kokat \u00e1ll\u00edtottak el\u0151, \u00e9s az eredm\u00e9nyek azt mutatt\u00e1k, hogy a szulfat\u00e1l\u00e1ssal t\u00f6rt\u00e9n\u0151 m\u00f3dos\u00edt\u00e1s optimaliz\u00e1lta a jamgy\u00f6k\u00e9r poliszacharidok fizikai-k\u00e9miai tulajdons\u00e1gait, \u00e9s kiv\u00e1l\u00f3 immunmodul\u00e1l\u00f3 aktivit\u00e1st mutatott. Arokiarajan \u00e9s munkat\u00e1rsai szulfat\u00e1ci\u00f3s m\u00f3dos\u00edt\u00e1ssal jav\u00edtott\u00e1k a tengeri moszat poliszacharidok v\u00edzben val\u00f3 oldhat\u00f3s\u00e1g\u00e1t \u00e9s tov\u00e1bb n\u00f6velt\u00e9k a poliszacharidok extrakci\u00f3s sebess\u00e9g\u00e9t. A biol\u00f3giai szerkezeti vegy\u00fcletek biol\u00f3giai aktivit\u00e1s\u00e1nak meghat\u00e1roz\u00f3 t\u00e9nyez\u0151je, Tao \u00e9s munkat\u00e1rsai term\u00e9szetes gombapoliszacharidok szulf\u00e1tozott sz\u00e1rmaz\u00e9kainak in vivo \u00e9s in vitro tumorellenes aktivit\u00e1s\u00e1t hasonl\u00edtott\u00e1k \u00f6ssze kl\u00f3rszulfonosav-piridin m\u00f3dszerrel, \u00e9s meg\u00e1llap\u00edtott\u00e1k, hogy a szulf\u00e1tozott sz\u00e1rmaz\u00e9kok in vitro g\u00e1tl\u00e1si ar\u00e1nya magasabb volt a HepG2 sejteken, mint az eredeti poliszacharidok\u00e9.<br \/>\nA Plantago ovata Forsk, a Plantago nemzets\u00e9ghez tartoz\u00f3 sz\u00e1r\u00edtott \u00e9s \u00e9rett mag, egy hagyom\u00e1nyos gy\u00f3gyn\u00f6v\u00e9ny, amelyet a k\u00ednai Hszincsiangban \u00e9lelmiszerk\u00e9nt \u00e9s gy\u00f3gyszerk\u00e9nt haszn\u00e1lnak. A Plantago asiatica hasmen\u00e9scsillap\u00edt\u00f3, vizelethajt\u00f3, f\u00e1jdalomcsillap\u00edt\u00f3, h\u0151cs\u00f6kkent\u0151, duzzanatcs\u00f6kkent\u0151 \u00e9s toroktiszt\u00edt\u00f3 hat\u00e1s\u00fa. Els\u0151sorban olyan betegs\u00e9gek kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k, mint a nefritisz-\u00f6d\u00e9ma, h\u00fagy\u00fati fert\u0151z\u00e9sek, gyakori vizel\u00e9s, f\u00e1jdalmas vizel\u00e9s, v\u00e9res vizel\u00e9s \u00e9s hasmen\u00e9s. A Plantago asiatica poliszacharidjai nagy viszkozit\u00e1ssal rendelkeznek, ami olyan \u00e9lettani funkci\u00f3kkal ruh\u00e1zza fel, mint a belek nedves\u00edt\u00e9se, a b\u00e9lmozg\u00e1s el\u0151seg\u00edt\u00e9se \u00e9s a b\u00e9lrendszer eg\u00e9szs\u00e9g\u00e9nek el\u0151seg\u00edt\u00e9se. Ez azonban k\u00e9nyelmetlens\u00e9get is okoz a termel\u00e9s, a kutat\u00e1s \u00e9s az alkalmaz\u00e1s sor\u00e1n. Ez a k\u00e9rd\u00e9s sz\u00e9les k\u00f6rben \u00e9rintett, de az el\u0151rel\u00e9p\u00e9s lass\u00fa volt. Ez\u00e9rt \u00faj m\u00f3dszereket kell kidolgozni a Plantago asiatica poliszacharidok viszkozit\u00e1s\u00e1nak hat\u00e9kony cs\u00f6kkent\u00e9s\u00e9re, mik\u00f6zben alacsony k\u00f6lts\u00e9get, szerkezeti integrit\u00e1st \u00e9s aktivit\u00e1st biztos\u00edtanak, a Plantago asiatica poliszacharidok tov\u00e1bbi fejleszt\u00e9s\u00e9nek \u00e9s felhaszn\u00e1l\u00e1s\u00e1nak el\u0151mozd\u00edt\u00e1sa \u00e9s a gazdas\u00e1gi el\u0151ny\u00f6k jav\u00edt\u00e1sa \u00e9rdek\u00e9ben. Eddig nem jelentek meg jelent\u00e9sek a Plantago asiatica poliszacharidok szerkezeti m\u00f3dos\u00edt\u00e1s\u00e1r\u00f3l, valamint biol\u00f3giai aktivit\u00e1sukr\u00f3l \u00e9s szerkezeti jellemz\u0151ikr\u0151l.<br \/>\nEz\u00e9rt ez a tanulm\u00e1ny els\u0151sorban a Plantago asiatica poliszacharidjaira, mint kutat\u00e1si t\u00e1rgyra \u00f6sszpontos\u00edt. Az alacsony viszkozit\u00e1s\u00fa Plantago asiatica poliszacharidokat szulfat\u00e1l\u00e1si m\u00f3dszerrel \u00e1ll\u00edtottuk el\u0151, majd izol\u00e1ltuk \u00e9s tiszt\u00edtottuk, hogy homog\u00e9n poliszacharidokat \u00e1ll\u00edtsunk el\u0151. El\u0151zetesen megvizsg\u00e1lt\u00e1k a szerkezeti jellemz\u0151ket, \u00e9s antioxid\u00e1ns aktivit\u00e1sukat in vitro antioxid\u00e1ns k\u00eds\u00e9rletekkel \u00e9rt\u00e9kelt\u00e9k. Tudom\u00e1sunk szerint ez az els\u0151 tanulm\u00e1ny a Plantago asiatica poliszacharidok szulfat\u00e1l\u00e1s\u00e1r\u00f3l a viszkozit\u00e1s cs\u00f6kkent\u00e9se \u00e9rdek\u00e9ben.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4933\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-105.png\" alt=\"\" width=\"696\" height=\"259\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4934\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-91.png\" alt=\"\" width=\"1005\" height=\"387\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-91.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-91-768x296.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4935\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-87.png\" alt=\"\" width=\"1005\" height=\"430\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-87.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-87-768x329.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4936\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-76.png\" alt=\"\" width=\"1005\" height=\"249\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-76.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-76-768x190.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4937\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-70.png\" alt=\"\" width=\"1005\" height=\"497\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-70.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-70-768x380.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4938\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-62.png\" alt=\"\" width=\"1005\" height=\"252\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-62.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-62-768x193.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4939\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-59.png\" alt=\"\" width=\"1005\" height=\"495\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-59.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-59-768x378.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4940\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-52.png\" alt=\"\" width=\"1005\" height=\"450\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-52.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-52-768x344.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4941\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-46.png\" alt=\"\" width=\"1005\" height=\"551\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-46.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-46-768x421.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4942\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-39.png\" alt=\"\" width=\"1005\" height=\"547\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-39.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-39-768x418.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4943\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-33.png\" alt=\"\" width=\"471\" height=\"324\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4944\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-29.png\" alt=\"\" width=\"1005\" height=\"457\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-29.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-29-768x349.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4945\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-24.png\" alt=\"\" width=\"1005\" height=\"385\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-24.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-24-768x294.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4946\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-20.png\" alt=\"\" width=\"1005\" height=\"382\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-20.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-20-768x292.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4947\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-15.png\" alt=\"\" width=\"1005\" height=\"381\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-15.png 1005w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-15-768x291.png 768w\" sizes=\"(max-width: 1005px) 100vw, 1005px\" \/><br \/>\nA Plantago asiatica poliszacharidok magas viszkozit\u00e1si jellemz\u0151i miatt a tiszt\u00edt\u00e1s \u00e9s az aktivit\u00e1s kimutat\u00e1sa nem v\u00e9gezhet\u0151 el. Ebben a tanulm\u00e1nyban a Plantago asiatica var. asiatica (POFP) poliszacharidok m\u00f3dos\u00edt\u00e1s\u00e1ra szulf\u00e1toz\u00e1st alkalmaztak, \u00e9s a m\u00f3dos\u00edtott poliszacharidok viszkozit\u00e1sa jelent\u0151sen cs\u00f6kkent. K\u00e9t homog\u00e9n poliszacharidot \u00e1ll\u00edtottunk el\u0151 a POFP-S elv\u00e1laszt\u00e1s\u00e1val \u00e9s tiszt\u00edt\u00e1s\u00e1val. A POFP-S1-ben a poliszacharidok, gl\u00fckuronsavak \u00e9s szulf\u00e1tcsoportok helyettes\u00edt\u00e9si foka \u00e9s tisztas\u00e1ga 38,96%, 2,91%, 0,364% \u00e9s 94,20% volt; a POFP-S2-ben a poliszacharidok, uronsavak \u00e9s szulf\u00e1tcsoportok helyettes\u00edt\u00e9si foka 52 volt.55%, 3,68%, 1,080%, illetve 98,89%, \u00e9s egyik poliszacharidban sem mutattak ki feh\u00e9rj\u00e9t; K\u00f6z\u00fcl\u00fck a POFP-S1 viszonylag nagy molekulat\u00f6meggel \u00e9s b\u0151s\u00e9ges monoszacharid komponensekkel rendelkezik. Az UV- \u00e9s FT-IR-spektroszk\u00f3pia kimutatta, hogy mind a POFP-S1, mind a POFP-S2 tipikusan szulfat\u00e1lt poliszacharidokra jellemz\u0151 abszorpci\u00f3s cs\u00facsokat mutat, ami a sikeres szulfat\u00e1ci\u00f3s m\u00f3dos\u00edt\u00e1sra utal; a r\u00f6ntgendiffrakci\u00f3s (XRD) \u00e9s a Kong\u00f3-v\u00f6r\u00f6s k\u00eds\u00e9rletek kimutatt\u00e1k, hogy a POFP-S2 egy olyan poliszacharid, amely egyedi spir\u00e1lis szerkezettel rendelkezik, amelyben krist\u00e1lyos \u00e9s amorf f\u00e1zisok egyar\u00e1nt el\u0151fordulnak. Az antioxid\u00e1ns aktivit\u00e1s tekintet\u00e9ben a POFP-S1 poliszacharid a POFP-S2-hez k\u00e9pest er\u0151sebb k\u00e9pess\u00e9ggel rendelkezik a DPPH- \u00e9s ABTS-gy\u00f6k\u00f6k elnyel\u00e9s\u00e9re, ami \u00f6sszef\u00fcgghet a nagyobb molekulat\u00f6meggel \u00e9s a monoszacharid-\u00f6sszet\u00e9tellel (gl\u00fck\u00f3z). A POFP-S2 er\u0151sebb k\u00e9pess\u00e9ggel rendelkezik a hidroxilgy\u00f6k\u00f6k elnyel\u00e9s\u00e9re, ami a POFP-S2 poliszacharidban l\u00e9v\u0151 szulf\u00e1tcsoportok magasabb fok\u00fa szubsztit\u00faci\u00f3j\u00e1nak tulajdon\u00edthat\u00f3. Ez a tanulm\u00e1ny irodalmi alapot ny\u00fajt a Plantago asiatica poliszacharidok szerkezet\u00e9nek \u00e9s aktivit\u00e1s\u00e1nak tov\u00e1bbi vizsg\u00e1lat\u00e1hoz, valamint elm\u00e9leti alapot ny\u00fajt a potenci\u00e1lis gy\u00f3gy\u00e1szati \u00e9s ehet\u0151 term\u00e9kek kifejleszt\u00e9s\u00e9hez, \u00e9s \u00f6tleteket ad a poliszacharidok szulfat\u00e1ci\u00f3s kutat\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Preparation of low viscosity polysaccharides from Plantago asiatica by sulfation and their structural characterization and antioxidant activity Polysaccharides are abundant in animals, plants, and microorganisms, and are widely used in the food and pharmaceutical industries due to their low toxicity and excellent biological activity. Modern research has shown that polysaccharides have various functions such as [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Preparation of low viscosity polysaccharides from Plantago asiatica by sulfation and their structural characterization and antioxidant activity - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/gyalogakac-mag\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preparation of low viscosity polysaccharides from Plantago asiatica by sulfation and their structural characterization and antioxidant activity - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Preparation of low viscosity polysaccharides from Plantago asiatica by sulfation and their structural characterization and antioxidant activity Polysaccharides are abundant in animals, plants, and microorganisms, and are widely used in the food and pharmaceutical industries due to their low toxicity and excellent biological activity. 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