{"id":4819,"date":"2024-08-04T15:53:45","date_gmt":"2024-08-04T15:53:45","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=4819"},"modified":"2024-08-04T15:53:45","modified_gmt":"2024-08-04T15:53:45","slug":"burdock-fruit","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/burdock-fruit\/","title":{"rendered":"A bojtorj\u00e1ngy\u00f6k\u00e9rb\u0151l t\u00f6rt\u00e9n\u0151 poliszacharid kivon\u00e1si folyamat optimaliz\u00e1l\u00e1sa v\u00e1laszfel\u00fclet-m\u00f3dszertan seg\u00edts\u00e9g\u00e9vel \u00e9s a sejtekre gyakorolt gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1nak vizsg\u00e1lata"},"content":{"rendered":"<p>A bojtorj\u00e1ngy\u00f6k\u00e9rb\u0151l t\u00f6rt\u00e9n\u0151 poliszacharid kivon\u00e1si folyamat optimaliz\u00e1l\u00e1sa v\u00e1laszfel\u00fclet-m\u00f3dszertan seg\u00edts\u00e9g\u00e9vel \u00e9s a sejtekre gyakorolt gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1s\u00e1nak vizsg\u00e1lata<br \/>\nAz Arctium lappa L., az Asteraceae n\u00f6v\u00e9ny \u00e9rett \u00e9s sz\u00e1r\u00edtott term\u00e9se szerepel a K\u00ednai Gy\u00f3gyszerk\u00f6nyv 2020-as kiad\u00e1s\u00e1ban. A modern kutat\u00e1sok azt mutatj\u00e1k, hogy az Arctium lapp\u00e1t sz\u00e9les k\u00f6rben tanulm\u00e1nyozt\u00e1k k\u00fcl\u00f6nb\u00f6z\u0151 farmakol\u00f3giai hat\u00e1sai miatt, mint p\u00e9ld\u00e1ul gyullad\u00e1scs\u00f6kkent\u0151, daganatellenes, cukorbetegs\u00e9g-nefrop\u00e1tia elleni, immunszab\u00e1lyoz\u00f3, v\u00edrusellenes, hipoglik\u00e9mi\u00e1s, vizelethajt\u00f3 \u00e9s tiszt\u00edt\u00f3 hat\u00e1sai. A bojtorj\u00e1nmag hat\u00f3anyagainak jelenlegi kutat\u00e1sa azonban els\u0151sorban a lign\u00e1nokra \u00f6sszpontos\u00edt, m\u00edg a poliszacharidokat, mint a gy\u00fcm\u00f6lcsalap\u00fa hagyom\u00e1nyos k\u00ednai orvosl\u00e1s egyik f\u0151 \u00f6sszetev\u0151j\u00e9t, kev\u00e9sb\u00e9 tanulm\u00e1nyozt\u00e1k a bojtorj\u00e1nmagban. A gyullad\u00e1s a szervezet immunrendszer\u00e9nek els\u0151 v\u00e9delmi vonala \u00e9s a szervezet term\u00e9szetes v\u00e9dekez\u0151 reakci\u00f3ja. A hossz\u00fa t\u00e1v\u00fa \u00e9s kr\u00f3nikus gyullad\u00e1s azonban olyan betegs\u00e9gek kialakul\u00e1s\u00e1hoz vezethet, mint a l\u00e1z, az asztma, az \u00e9relmeszesed\u00e9s, az \u00edz\u00fcleti gyullad\u00e1s, a neurodegenerat\u00edv betegs\u00e9gek \u00e9s m\u00e9g a r\u00e1k is. Jelenleg a gyullad\u00e1s kezel\u00e9se els\u0151sorban a szteroid \u00e9s a nem szteroid gyullad\u00e1scs\u00f6kkent\u0151kre \u00f6sszpontos\u00edt, de ezek nem haszn\u00e1lhat\u00f3k hossz\u00fa ideig, mert mell\u00e9khat\u00e1sokat okozhatnak, mint p\u00e9ld\u00e1ul magas v\u00e9rnyom\u00e1s, csontritkul\u00e1s, immunszuppresszi\u00f3, v\u00e9rz\u00e9ses gyomorhurut, fels\u0151 gyomor-b\u00e9lrendszeri fek\u00e9lyek, m\u00e1jk\u00e1rosod\u00e1s, allergia stb. Ez\u00e9rt s\u00fcrg\u0151s egy biztons\u00e1gos \u00e9s hat\u00e9kony \u00faj gy\u00f3gyszerforr\u00e1s kifejleszt\u00e9se. Az elm\u00falt \u00e9vekben a term\u00e9szetes poliszacharidok sz\u00e9les k\u00f6r\u0171 figyelmet kaptak biztons\u00e1goss\u00e1guk, hozz\u00e1f\u00e9rhet\u0151s\u00e9g\u00fck \u00e9s j\u00f3 gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1suk miatt.<br \/>\nEz\u00e9rt az egyt\u00e9nyez\u0151s felt\u00e9telek vizsg\u00e1lata alapj\u00e1n ez a tanulm\u00e1ny elfogadta a Box Behnken-m\u00f3dszert a v\u00e1laszfel\u00fcletben, hogy h\u00e1romt\u00e9nyez\u0151s, h\u00e1romszint\u0171 k\u00eds\u00e9rleti tervet v\u00e9gezzen. A bojtorj\u00e1nmag poliszacharidok extrakci\u00f3s ar\u00e1nya alapj\u00e1n megalkott\u00e1k a bojtorj\u00e1nmag poliszacharid extrakci\u00f3s folyamat\u00e1nak optim\u00e1lis \u00f6sszet\u00e9tel\u00e9t. A RAW 246.7 sejtek lipopoliszachariddal (LPS) kiv\u00e1ltott gyullad\u00e1sos modellj\u00e9nek l\u00e9trehoz\u00e1s\u00e1val el\u0151zetes vizsg\u00e1latokat v\u00e9geztek a bojtorj\u00e1nmag poliszacharidok gyullad\u00e1scs\u00f6kkent\u0151 mechanizmusair\u00f3l, tudom\u00e1nyos alapot szolg\u00e1ltatva \u00faj gyullad\u00e1scs\u00f6kkent\u0151 gy\u00f3gyszerek kifejleszt\u00e9s\u00e9hez \u00e9s a bojtorj\u00e1nmag poliszacharidok \u00e1tfog\u00f3 felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4820\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png\" alt=\"\" width=\"815\" height=\"246\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png 815w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96-768x232.png 768w\" sizes=\"(max-width: 815px) 100vw, 815px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4821\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-6.jpg\" alt=\"\" width=\"636\" height=\"715\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4822\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-80.png\" alt=\"\" width=\"809\" height=\"566\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-80.png 809w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-80-768x537.png 768w\" sizes=\"(max-width: 809px) 100vw, 809px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4823\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-68.png\" alt=\"\" width=\"580\" height=\"656\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4824\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-65.png\" alt=\"\" width=\"634\" height=\"624\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4825\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-58.png\" alt=\"\" width=\"634\" height=\"331\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4826\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-54.png\" alt=\"\" width=\"796\" height=\"351\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-54.png 796w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-54-768x339.png 768w\" sizes=\"(max-width: 796px) 100vw, 796px\" \/>Ez a cikk a bojtorj\u00e1nmag poliszacharidjainak extrakci\u00f3s folyamat\u00e1ban h\u00e1rom t\u00e9nyez\u0151 (szil\u00e1rd-folyad\u00e9k ar\u00e1ny, id\u0151 \u00e9s h\u0151m\u00e9rs\u00e9klet) tartom\u00e1nymeghat\u00e1roz\u00e1si vizsg\u00e1lat\u00e1t v\u00e9gzi. Ennek alapj\u00e1n egy h\u00e1romt\u00e9nyez\u0151s kombin\u00e1ci\u00f3s k\u00eds\u00e9rleti tervet hajtunk v\u00e9gre Box Behnken seg\u00edts\u00e9g\u00e9vel. A bojtorj\u00e1nmag poliszacharidok t\u00e9nyleges extrakci\u00f3s sebess\u00e9g\u00e9nek megfelel\u0151en a bojtorj\u00e1nmag poliszacharidok optim\u00e1lis extrakci\u00f3s folyamat\u00e1nak felt\u00e9teleit kaptuk meg (szil\u00e1rd-folyad\u00e9k ar\u00e1ny = 1:15g\/ml, extrakci\u00f3s id\u0151 3 \u00f3ra, extrakci\u00f3s h\u0151m\u00e9rs\u00e9klet 80 \u2103). A k\u00fcl\u00f6nb\u00f6z\u0151 koncentr\u00e1ci\u00f3j\u00fa bojtorj\u00e1nmag-poliszacharidok sejtgyullad\u00e1sban kifejtett hat\u00e1smechanizmus\u00e1nak vizsg\u00e1lat\u00e1val meg\u00e1llap\u00edtott\u00e1k, hogy a bojtorj\u00e1nmag-poliszacharidok k\u00e9pesek g\u00e1tolni a TNF - \u03b1 \u00e9s IL-6 szekr\u00e9ci\u00f3j\u00e1t a RAW 264.7 sejtek LPS \u00e1ltal induk\u00e1lt fel\u00fcl\u00fasz\u00f3j\u00e1ban, \u00e9s immunszab\u00e1lyoz\u00f3 szerepet j\u00e1tszhatnak a TLR4\/MyD88\/NF - \u03ba B \u00fatvonal relev\u00e1ns feh\u00e9rj\u00e9inek szab\u00e1lyoz\u00e1s\u00e1n kereszt\u00fcl. Ez a tanulm\u00e1ny tudom\u00e1nyos alapot teremthet a bojtorj\u00e1nmag poliszacharidok fejleszt\u00e9s\u00e9hez \u00e9s alkalmaz\u00e1s\u00e1hoz, \u00e9s technikai referenci\u00e1kat biztos\u00edthat a bojtorj\u00e1n gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1sainak fejleszt\u00e9s\u00e9hez \u00e9s alkalmaz\u00e1s\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells Arctium lappa L., a mature and dried fruit of the Asteraceae plant, is included in the 2020 edition of the Chinese Pharmacopoeia. Modern research shows that Arctium lappa has been widely studied because of its [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/burdock-fruit\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells Arctium lappa L., a mature and dried fruit of the Asteraceae plant, is included in the 2020 edition of the Chinese Pharmacopoeia. Modern research shows that Arctium lappa has been widely studied because of its [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/burdock-fruit\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-04T15:53:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/\",\"url\":\"https:\/\/longchangextracts.com\/burdock-fruit\/\",\"name\":\"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png\",\"datePublished\":\"2024-08-04T15:53:45+00:00\",\"dateModified\":\"2024-08-04T15:53:45+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/burdock-fruit\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/#primaryimage\",\"url\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png\",\"contentUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-96.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/burdock-fruit\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Optimaliz\u00e1l\u00e1sa poliszacharid extrakci\u00f3s folyamat bojtorj\u00e1n gy\u00f6k\u00e9r seg\u00edts\u00e9g\u00e9vel v\u00e1lasz fel\u00fclet m\u00f3dszertan \u00e9s tanulm\u00e1nyozza a gyullad\u00e1scs\u00f6kkent\u0151 hat\u00e1sa a sejtekre - K\u00edna Chemical Manufacturer","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/burdock-fruit\/","og_locale":"hu_HU","og_type":"article","og_title":"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells - China Chemical Manufacturer","og_description":"Optimization of polysaccharide extraction process from burdock root using response surface methodology and study on its anti-inflammatory effect on cells Arctium lappa L., a mature and dried fruit of the Asteraceae plant, is included in the 2020 edition of the Chinese Pharmacopoeia. 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