{"id":4624,"date":"2024-08-04T15:03:19","date_gmt":"2024-08-04T15:03:19","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=4624"},"modified":"2024-08-04T15:03:19","modified_gmt":"2024-08-04T15:03:19","slug":"chitin","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/kitin\/","title":{"rendered":"A cik\u00e1dah\u00e9jb\u00f3l sz\u00e1rmaz\u00f3 kitin extrakci\u00f3s elj\u00e1r\u00e1s\u00e1nak optimaliz\u00e1l\u00e1sa, valamint antioxid\u00e1ns aktivit\u00e1s\u00e1nak \u00e9s v\u00e9rz\u00e9scsillap\u00edt\u00f3 hat\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9se"},"content":{"rendered":"<p>A cik\u00e1dah\u00e9jb\u00f3l sz\u00e1rmaz\u00f3 kitin extrakci\u00f3s elj\u00e1r\u00e1s\u00e1nak optimaliz\u00e1l\u00e1sa, valamint antioxid\u00e1ns aktivit\u00e1s\u00e1nak \u00e9s v\u00e9rz\u00e9scsillap\u00edt\u00f3 hat\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9se<br \/>\nA kitin, m\u00e1s n\u00e9ven kitoz\u00e1n egy line\u00e1ris makromolekul\u00e1s biopoliszacharid, amely \u03b2 -1,4-glikozidos k\u00f6t\u00e9sekkel \u00f6sszekapcsolt N-acetil-2-amino-2-deoxi-D-gl\u00fckopiran\u00f3z egys\u00e9gekb\u0151l \u00e1ll. F\u00e9lig \u00e1tl\u00e1tsz\u00f3, lapszer\u0171 szil\u00e1rd anyag, \u00e9s a poliszacharidl\u00e1ncok k\u00f6z\u00f6tti hidrog\u00e9nk\u00f6t\u00e9s miatt a kitin v\u00edzben, h\u00edg savakban, h\u00edg b\u00e1zisokban vagy \u00e1ltal\u00e1nos szerves old\u00f3szerekben nem old\u00f3dik. A kitin sz\u00e9les k\u00f6rben jelen van az alacsonyabb rend\u0171 \u00edzeltl\u00e1b\u00faak, rovarok p\u00e1nc\u00e9lj\u00e1ban, valamint bizonyos alg\u00e1k \u00e9s gomb\u00e1k sejtfal\u00e1ban mind tengeri, mind sz\u00e1razf\u00f6ldi k\u00f6rnyezetben. Az extrakci\u00f3s m\u00f3dszerek k\u00f6z\u00e9 tartoznak a sav-b\u00e1zis, az enzimatikus hidrol\u00edzis, az EDTA, a mikrobi\u00e1lis ferment\u00e1ci\u00f3 \u00e9s az ionos folyad\u00e9kos m\u00f3dszerek. A kitinnek olyan biol\u00f3giai hat\u00e1sai vannak, mint az antioxid\u00e1ns, v\u00e9rz\u00e9scsillap\u00edt\u00f3, antibakteri\u00e1lis, daganatellenes, hipoglik\u00e9mi\u00e1s, v\u00e9rnyom\u00e1scs\u00f6kkent\u0151, lipidcs\u00f6kkent\u0151 \u00e9s immunszab\u00e1lyoz\u00f3. Nem m\u00e9rgez\u0151, j\u00f3 biokompatibilit\u00e1sa, biol\u00f3giai lebonthat\u00f3s\u00e1ga \u00e9s enzimes lebonthat\u00f3s\u00e1ga miatt sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k az olyan biomedicin\u00e1lis ter\u00fcleteken, mint a gy\u00f3gyszeradagol\u00e1s, a sz\u00f6vettechnol\u00f3gia, a sebgy\u00f3gyul\u00e1s \u00e9s a r\u00e1kkezel\u00e9s.<br \/>\nA Periostracum Cicadae, m\u00e1s n\u00e9ven Cicadae, a kab\u00f3c\u00e1k csal\u00e1dj\u00e1ba tartoz\u00f3 rovarok fekete sz\u00f6csk\u00e9inek a vedl\u00e9s ut\u00e1ni vedl\u00e9sh\u00e9ja. K\u00e9miai \u00f6sszet\u00e9tele f\u0151k\u00e9nt kitint, feh\u00e9rj\u00e9t, szervetlen s\u00f3kat, aminosavakat, nyomelemeket stb. tartalmaz. A K\u00edn\u00e1ban \u00e1ltal\u00e1nosan haszn\u00e1lt hagyom\u00e1nyos k\u00ednai gy\u00f3gy\u00e1szatban a sz\u00e9l \u00e9s a h\u0151 eloszlat\u00e1s\u00e1ra, a torok enyh\u00edt\u00e9s\u00e9re, a ki\u00fct\u00e9sek \u00e1that\u00e1s\u00e1ra, a g\u00f6rcs\u00f6k enyh\u00edt\u00e9s\u00e9re, valamint a l\u00e1t\u00e1s jav\u00edt\u00e1s\u00e1ra \u00e9s a hom\u00e1lyok enyh\u00edt\u00e9s\u00e9re van hat\u00e1ssal. Tanulm\u00e1nyok kimutatt\u00e1k, hogy a kab\u00f3camoly, mint alternat\u00edv kitinforr\u00e1s, alacsony acetil\u00e1lts\u00e1gi fokkal, krist\u00e1lyoss\u00e1ggal, termikus tulajdons\u00e1gokkal \u00e9s j\u00f3 \u00f6kol\u00f3giai biztons\u00e1ggal rendelkezik. A kab\u00f3cahulla magas \u00e1ra \u00e9s a kitinre vonatkoz\u00f3 r\u00f6gz\u00edtett min\u0151s\u00e9gi szabv\u00e1nyok hi\u00e1nya miatt azonban a kab\u00f3cahulla kitinnel kapcsolatos kutat\u00e1sok jelenleg lassan haladnak. Ez a tanulm\u00e1ny ultrahanggal t\u00e1mogatott hagyom\u00e1nyos sav-b\u00e1zis m\u00f3dszert alkalmazott a kitin kivon\u00e1s\u00e1ra a kab\u00f3camolyb\u00f3l, ler\u00f6vid\u00edtette az extrakci\u00f3s ciklust, \u00e9s optimaliz\u00e1lta az extrakci\u00f3s folyamatot egyt\u00e9nyez\u0151s \u00e9s ortogon\u00e1lis k\u00eds\u00e9rletek seg\u00edts\u00e9g\u00e9vel. A kivonat antioxid\u00e1ns aktivit\u00e1s\u00e1t \u00e9s v\u00e9rz\u00e9scsillap\u00edt\u00f3 hat\u00e1s\u00e1t is meghat\u00e1roztuk, ami fontos referencia jelent\u0151s\u00e9ggel b\u00edr a kab\u00f3camolyok kitinj\u00e9nek kutat\u00e1s\u00e1nak \u00e9s alkalmaz\u00e1s\u00e1nak el\u0151mozd\u00edt\u00e1sa szempontj\u00e1b\u00f3l.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4625\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-77.png\" alt=\"\" width=\"774\" height=\"197\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-77.png 774w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-77-768x195.png 768w\" sizes=\"(max-width: 774px) 100vw, 774px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4626\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-67.png\" alt=\"\" width=\"775\" height=\"199\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-67.png 775w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-67-768x197.png 768w\" sizes=\"(max-width: 775px) 100vw, 775px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4627\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-63.png\" alt=\"\" width=\"776\" height=\"196\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-63.png 776w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-63-768x194.png 768w\" sizes=\"(max-width: 776px) 100vw, 776px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4628\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-52.png\" alt=\"\" width=\"800\" height=\"655\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-52.png 800w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-52-768x629.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4629\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-51.png\" alt=\"\" width=\"441\" height=\"575\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4630\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-47.png\" alt=\"\" width=\"461\" height=\"275\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4631\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-44.png\" alt=\"\" width=\"464\" height=\"301\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4632\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-39.png\" alt=\"\" width=\"460\" height=\"282\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4633\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-34.png\" alt=\"\" width=\"801\" height=\"577\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-34.png 801w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-34-768x553.png 768w\" sizes=\"(max-width: 801px) 100vw, 801px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4634\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-30.png\" alt=\"\" width=\"801\" height=\"556\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-30.png 801w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-30-768x533.png 768w\" sizes=\"(max-width: 801px) 100vw, 801px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4635\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-27.png\" alt=\"\" width=\"807\" height=\"556\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-27.png 807w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-27-768x529.png 768w\" sizes=\"(max-width: 807px) 100vw, 807px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4636\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-23.png\" alt=\"\" width=\"457\" height=\"256\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4637\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-20.png\" alt=\"\" width=\"455\" height=\"256\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4638\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-17.png\" alt=\"\" width=\"455\" height=\"260\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4639\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-13.png\" alt=\"\" width=\"455\" height=\"669\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4640\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-11.png\" alt=\"\" width=\"455\" height=\"304\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-11.png 455w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-11-325x217.png 325w\" sizes=\"(max-width: 455px) 100vw, 455px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-4641\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/17-10.png\" alt=\"\" width=\"454\" height=\"320\" \/><br \/>\nAz ultrahanggal seg\u00edtett sav-b\u00e1zis extrakci\u00f3 optim\u00e1lis folyamatparam\u00e9tereit a cik\u00e1szok moltsav\u00e1b\u00f3l sz\u00e1rmaz\u00f3 kitin ultrahanggal seg\u00edtett sav-b\u00e1zis extrakci\u00f3j\u00e1hoz ortogon\u00e1lis k\u00eds\u00e9rletekkel kombin\u00e1lt egyt\u00e9nyez\u0151s k\u00eds\u00e9rletek seg\u00edts\u00e9g\u00e9vel kaptuk meg, bele\u00e9rtve a k\u00f6vetkez\u0151 ortogon\u00e1lis k\u00eds\u00e9rleteket: m\u00e9sztelen\u00edt\u00e9s: t\u00f6megfrakci\u00f3: 8% s\u00f3sav, h\u0151m\u00e9rs\u00e9klet: szobah\u0151m\u00e9rs\u00e9klet, szil\u00e1rd-folyad\u00e9k ar\u00e1ny: 1:25, ultrahang teljes\u00edtm\u00e9ny: 160W, ultrahang id\u0151: 150 perc; feh\u00e9rje elt\u00e1vol\u00edt\u00e1s: t\u00f6megfrakci\u00f3:  5% k\u00e1lium-permangan\u00e1t, 8% n\u00e1trium-biszulfit, h\u0151m\u00e9rs\u00e9klet: 90 \u2103, id\u0151: k\u00e1lium-permangan\u00e1t reakci\u00f3 60 percig, n\u00e1trium-biszulfit reakci\u00f3 90 percig. Az ultrahanggal seg\u00edtett m\u00e9sztelen\u00edt\u00e9s \u00e9s feh\u00e9rjementes\u00edt\u00e9s n\u00f6veli az old\u00f3szer penetr\u00e1ci\u00f3j\u00e1t, hat\u00e9konyan ler\u00f6vid\u00edtve az extrakci\u00f3s id\u0151t.<br \/>\nAz el\u0151zetes k\u00eds\u00e9rletben k\u00e1lium-hidroxid\/ karbamid vizes oldatot haszn\u00e1ltak alacsony h\u0151m\u00e9rs\u00e9kleten t\u00f6rt\u00e9n\u0151 fagyaszt\u00e1shoz \u00e9s felolvaszt\u00e1shoz a kab\u00f3cah\u00e1rtya kitinj\u00e9nek felold\u00e1s\u00e1hoz. A folyamat sor\u00e1n meg\u00e1llap\u00edtott\u00e1k, hogy maga a k\u00e1lium-hidroxid\/karbamid rendszer jelent\u0151s hat\u00e1ssal van a szabad gy\u00f6k\u00f6kre. Ez a tanulm\u00e1ny a kab\u00f3ca molt kitoz\u00e1nszuszpenzi\u00f3 antioxid\u00e1ns aktivit\u00e1s\u00e1t vizsg\u00e1lta. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy amikor a kab\u00f3ca molt kitoz\u00e1nszuszpenzi\u00f3 koncentr\u00e1ci\u00f3ja 18 mg\/ml volt, az ABTS szabadgy\u00f6k-lev\u00e1laszt\u00e1si ar\u00e1ny 91 volt.31%, ami er\u0151s szabad gy\u00f6kfog\u00f3 k\u00e9pess\u00e9get mutat; Amikor a kab\u00f3ca molt kitoz\u00e1n szuszpenzi\u00f3 koncentr\u00e1ci\u00f3ja 15mg\/ml, a DPPH szabad gy\u00f6k\u00f6k elsz\u00edv\u00e1si ar\u00e1nya 35,19%; Amikor a kab\u00f3ca molt kitoz\u00e1n szuszpenzi\u00f3 koncentr\u00e1ci\u00f3ja 20mg\/ml, az O2 szabad gy\u00f6k\u00f6k elsz\u00edv\u00e1si ar\u00e1nya 63,72%. A kitoz\u00e1n kiv\u00e1l\u00f3 antioxid\u00e1ns aktivit\u00e1s\u00e1nak oka az lehet, hogy a sav-b\u00e1zis extrakci\u00f3s folyamat sor\u00e1n r\u00e9szben deacetil\u00e1l\u00f3dott.<br \/>\nA k\u00e9mcs\u00f6ves m\u00f3dszert alkalmazt\u00e1k a ny\u00falv\u00e9r in vitro alvad\u00e1si idej\u00e9nek meghat\u00e1roz\u00e1s\u00e1ra k\u00fcl\u00f6nb\u00f6z\u0151 d\u00f3zis\u00fa kitoz\u00e1nporral. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a cik\u00e1damolyh\u00f3s kitoz\u00e1npor in vitro prokoagul\u00e1l\u00f3 k\u00e9pess\u00e9ge a cik\u00e1damolyh\u00f3s kitoz\u00e1n adagj\u00e1nak n\u00f6veked\u00e9s\u00e9vel n\u0151tt. Az azonos d\u00f3zis\u00fa Yunnan Baiyao porral \u00f6sszehasonl\u00edtva a cicada molt kitoz\u00e1npor in vitro prokoagul\u00e1ns k\u00e9pess\u00e9ge jelent\u0151sen jobb volt. A farokv\u00e1g\u00e1si m\u00f3dszert haszn\u00e1lt\u00e1k a cicada molt kitoz\u00e1npor k\u00fcl\u00f6nb\u00f6z\u0151 d\u00f3zisainak v\u00e9rz\u00e9si idej\u00e9nek \u00e9s mennyis\u00e9g\u00e9nek meghat\u00e1roz\u00e1s\u00e1ra egereken. Az eredm\u00e9nyek azt mutatt\u00e1k, hogy a cicada molt kitoz\u00e1npor \u00e9s a Yunnan Baiyao por pozit\u00edv kontrollcsoportja minden egyes d\u00f3zisban jelent\u0151sen ler\u00f6vid\u00edtheti a v\u00e9rz\u00e9si id\u0151t a vak kontrollcsoporthoz k\u00e9pest. A Yunnan Baiyao porral \u00f6sszehasonl\u00edtva ugyanabban az adagban jelent\u0151s k\u00fcl\u00f6nbs\u00e9gek voltak a v\u00e9rz\u00e9si id\u0151 \u00e9s a kitoz\u00e1n mennyis\u00e9g\u00e9ben, ami azt jelzi, hogy a cicada molt kitoz\u00e1n jobb v\u00e9rz\u00e9scsillap\u00edt\u00f3 k\u00e9pess\u00e9ggel rendelkezik, mint a Yunnan Baiyao. Az eg\u00e9r m\u00e1jv\u00e9rz\u00e9s modellj\u00e9nek l\u00e9trehoz\u00e1sa \u00e9s a seb v\u00e9rz\u00e9si idej\u00e9nek m\u00e9r\u00e9se azt mutatta, hogy a cicada molt kitoz\u00e1n jelent\u0151sen le tudta r\u00f6vid\u00edteni a m\u00e1jseb v\u00e9rz\u00e9si idej\u00e9t, \u00e9s az azonos d\u00f3zis\u00fa cicada molt kitoz\u00e1n adatai jobbak voltak, mint a Yunnan Baiyao pozit\u00edv kontroll\u00e9. A cicada molt kitoz\u00e1n j\u00f3 hat\u00e1ssal van a v\u00e9ralvad\u00e1s el\u0151seg\u00edt\u00e9s\u00e9re a szervezetben gazdag v\u00e9rtartalm\u00fa szervek, p\u00e9ld\u00e1ul a m\u00e1j v\u00e9rz\u0151 sebeiben, \u00e9s potenci\u00e1lisan fejleszthet\u0151 v\u00e9rz\u00e9scsillap\u00edt\u00f3 anyagk\u00e9nt egyes szervek seb\u00e9szeti reszekci\u00f3j\u00e1hoz.<\/p>","protected":false},"excerpt":{"rendered":"<p>Optimization of extraction process of chitin from cicada molt and evaluation of its antioxidant activity and hemostatic effect Chitin, also known as chitosan, is a linear macromolecule biopolysaccharide composed of N-acetyl-2-amino-2-deoxy-D-glucopyranose units connected by \u03b2 -1,4-glycosidic bonds. It is a semi transparent sheet-like solid, and due to the hydrogen bonding between polysaccharide chains, chitin is [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Optimization of extraction process of chitin from cicada molt and evaluation of its antioxidant activity and hemostatic effect - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/kitin\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimization of extraction process of chitin from cicada molt and evaluation of its antioxidant activity and hemostatic effect - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Optimization of extraction process of chitin from cicada molt and evaluation of its antioxidant activity and hemostatic effect Chitin, also known as chitosan, is a linear macromolecule biopolysaccharide composed of N-acetyl-2-amino-2-deoxy-D-glucopyranose units connected by \u03b2 -1,4-glycosidic bonds. 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