{"id":4507,"date":"2024-08-04T14:37:37","date_gmt":"2024-08-04T14:37:37","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=4507"},"modified":"2024-08-04T14:37:37","modified_gmt":"2024-08-04T14:37:37","slug":"rhizoma-drynariae","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/rhizoma-drynariae\/","title":{"rendered":"A csontt\u00f6red\u00e9k-folt UPLC-ujjlenyomata \u00e9s az alkalikus foszfat\u00e1z aktivit\u00e1s k\u00f6z\u00f6tti spektr\u00e1lis hat\u00e1s \u00f6sszef\u00fcgg\u00e9s\u00e9nek vizsg\u00e1lata hum\u00e1n MG63 csontsarcomasejtben"},"content":{"rendered":"

A csontt\u00f6red\u00e9k-folt UPLC-ujjlenyomata \u00e9s az alkalikus foszfat\u00e1z aktivit\u00e1s k\u00f6z\u00f6tti spektr\u00e1lis hat\u00e1s \u00f6sszef\u00fcgg\u00e9s\u00e9nek vizsg\u00e1lata hum\u00e1n MG63 csontsarcomasejtben
\nA Gu Duan Bu a Drynaria fortunei (Kunze) J. Sm. sz\u00e1r\u00edtott riz\u00f3m\u00e1ja, egy v\u00edzi s\u00e1rk\u00e1ny ortop\u00e9diai n\u00f6v\u00e9ny. Meleg term\u00e9szet\u0171, keser\u0171 \u00edz\u0171, \u00e9s a m\u00e1j- \u00e9s a vese meridi\u00e1nokhoz tartozik. Gy\u00f3gy\u00edt\u00f3 \u00e9s f\u00e1jdalomcsillap\u00edt\u00f3, a ves\u00e9ket toniz\u00e1l\u00f3 \u00e9s a csontokat er\u0151s\u00edt\u0151, valamint a szelet \u00e9s a foltokat el\u0171z\u0151 hat\u00e1sa van. A modern farmakol\u00f3giai \u00e9s klinikai vizsg\u00e1latok kimutatt\u00e1k, hogy a csontt\u00f6r\u00e9s elleni tonik\u00e1knak olyan hat\u00e1sai vannak, mint a csontritkul\u00e1s elleni, a t\u00f6r\u00e9sgy\u00f3gyul\u00e1st el\u0151seg\u00edt\u0151, a vesev\u00e9delem, a gyullad\u00e1scs\u00f6kkent\u00e9s \u00e9s a fogn\u00f6veked\u00e9s el\u0151seg\u00edt\u00e9se. K\u00e9miai \u00f6sszet\u00e9tel-vizsg\u00e1latok kimutatt\u00e1k, hogy a csontt\u00f6red\u00e9k-tonikumok f\u0151 hat\u00f3anyagai a flavonoidok, triterpenoidok, fenilpropanoidok \u00e9s fenolok. Sz\u00e1mos tanulm\u00e1ny kimutatta, hogy a csontvel\u0151 tonikumok jelent\u0151s ter\u00e1pi\u00e1s hat\u00e1ssal rendelkeznek a csontokkal kapcsolatos betegs\u00e9gek kezel\u00e9s\u00e9ben, \u00e9s in vitro k\u00eds\u00e9rletek kimutatt\u00e1k, hogy a csontvel\u0151 tonikumok el\u0151seg\u00edthetik az oszteoblasztok oszteog\u00e9n differenci\u00e1l\u00f3d\u00e1si k\u00e9pess\u00e9g\u00e9t. A csontvel\u0151-tonikumok konkr\u00e9t hat\u00f3anyagair\u00f3l azonban nem k\u00e9sz\u00fcltek jelent\u00e9sek. Az alkalikus foszfat\u00e1z (ALP) az oszteoblasztok differenci\u00e1l\u00f3d\u00e1s\u00e1nak \u00e9s \u00e9r\u00e9s\u00e9nek biomarkere, \u00e9s az ALP aktivit\u00e1si szintj\u00e9nek v\u00e1ltoz\u00e1sai felhaszn\u00e1lhat\u00f3k az oszteoblasztok differenci\u00e1l\u00f3d\u00e1si k\u00e9pess\u00e9g\u00e9nek meghat\u00e1roz\u00e1s\u00e1ra. Ez\u00e9rt ebben a k\u00eds\u00e9rletben elemezt\u00fck az UPLC-ujjlenyomat \u00e9s az ALP-aktivit\u00e1s spektruma k\u00f6z\u00f6tti kapcsolatot az emberi MG63 csontsarcomasejtek eset\u00e9ben, \u00e9s felt\u00e1rtuk az oszteoblasztok sz\u00e1m\u00e1ra haszn\u00e1lt csontt\u00f6red\u00e9k-tonikumok f\u0151 \u00f6sszetev\u0151it.
\nA hagyom\u00e1nyos k\u00ednai gy\u00f3gyszer spektrum\u00e1nak hat\u00e9konys\u00e1g\u00e1nak \u00e9rt\u00e9kel\u00e9si m\u00f3dja a k\u00e9miai komponens ujjlenyomat\u00e1nak \u00e9s farmakol\u00f3giai hat\u00e1sainak kombin\u00e1l\u00e1sa, hogy az ujjlenyomatban l\u00e9v\u0151 k\u00e9miai komponensek t\u00fckr\u00f6zz\u00e9k a megfelel\u0151 farmakol\u00f3giai hat\u00e1sokat, \u00e9s tiszt\u00e1zz\u00e1k az ujjlenyomat jellegzetes cs\u00facsai \u00e9s a farmakol\u00f3giai hat\u00e1sok k\u00f6z\u00f6tti kapcsolatot, meghat\u00e1rozz\u00e1k a megfelel\u0151 farmakol\u00f3giai anyagot, \u00e9s \u00edgy elv\u00e9gzik a hagyom\u00e1nyos k\u00ednai gy\u00f3gyszer min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9t \u00e9s farmakol\u00f3giai \u00e9rt\u00e9kel\u00e9s\u00e9t.
\nEbben a tanulm\u00e1nyban UPLC-ujjlenyomat-spektrumokat \u00e1ll\u00edtottak fel a nyers \u00e9s meleg csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151kr\u0151l, \u00e9s UPLC-Q-TOF-MS technol\u00f3gia seg\u00edts\u00e9g\u00e9vel azonos\u00edtott\u00e1k k\u00e9miai \u00f6sszetev\u0151iket. A sz\u00fcrke korrel\u00e1ci\u00f3s anal\u00edzist, a k\u00e9tv\u00e1ltoz\u00f3s korrel\u00e1ci\u00f3s anal\u00edzist \u00e9s a parci\u00e1lis legkisebb n\u00e9gyzetek m\u00f3dszer\u00e9t haszn\u00e1lt\u00e1k a csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151k ujjlenyomat-spektrumainak \u00e9s az ALP-aktivit\u00e1s spektr\u00e1lis hat\u00e1skapcsolat\u00e1nak megalkot\u00e1s\u00e1ra, referenci\u00e1t biztos\u00edtva a csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151k farmakol\u00f3giai anyagalapj\u00e1nak \u00e9s min\u0151s\u00e9gellen\u0151rz\u00e9s\u00e9nek felder\u00edt\u00e9s\u00e9hez.<\/p>\n

\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"\"
\nEbben a tanulm\u00e1nyban UPLC-m\u00f3dszert alkalmaztak t\u00f6bb hull\u00e1mhossz\u00fa detekt\u00e1l\u00e1ssal kombin\u00e1lva a csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151k \u00e9s a forr\u00f3 term\u00e9kek ujjlenyomat-spektrum\u00e1nak meg\u00e1llap\u00edt\u00e1s\u00e1ra. A csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151k \u00e9s a forr\u00f3 term\u00e9kek k\u00fcl\u00f6nb\u00f6z\u0151 t\u00e9telei k\u00f6z\u00f6tt 12 k\u00f6z\u00f6s cs\u00facs volt, \u00e9s a hasonl\u00f3s\u00e1g nagyobb volt, mint 0,9, ami nagyfok\u00fa hasonl\u00f3s\u00e1got \u00e9s nem egy\u00e9rtelm\u0171 megk\u00fcl\u00f6nb\u00f6ztet\u00e9st jelez a kett\u0151 k\u00f6z\u00f6tt. Az ALP az oszteoblasztok differenci\u00e1l\u00f3d\u00e1s\u00e1nak \u00e9s \u00e9r\u00e9s\u00e9nek biomarkere, \u00e9s a csontk\u00e9pz\u0151d\u00e9s egyik biok\u00e9miai mutat\u00f3ja. Az oszteoblasztok differenci\u00e1l\u00f3d\u00e1si k\u00e9pess\u00e9ge meghat\u00e1rozhat\u00f3 az ALP aktivit\u00e1si szintj\u00e9nek v\u00e1ltoz\u00e1s\u00e1val. Kor\u00e1bbi tanulm\u00e1nyok kimutatt\u00e1k, hogy a csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u00e9s el\u0151seg\u00edtheti az oszteoblasztok differenci\u00e1l\u00f3d\u00e1s\u00e1t. Ebben a vizsg\u00e1latban csontt\u00f6red\u00e9k-kieg\u00e9sz\u00edt\u0151ket \u00e9s sk\u00e1l\u00e1kat alkalmaztunk MG63 sejteken, hogy elemezz\u00fck az ALP-aktivit\u00e1sra gyakorolt hat\u00e1sukat. Az eredm\u00e9nyek azt mutatj\u00e1k, hogy ugyanaz a csontt\u00f6red\u00e9k-t\u00e9tel jelent\u0151sen el\u0151seg\u00edtheti az MG63 sejtek ALP-szekr\u00e9ci\u00f3j\u00e1t a homok leforr\u00e1z\u00e1st k\u00f6vet\u0151en. A csontt\u00f6red\u00e9kekben \u00e9s a jav\u00edt\u00e1sban l\u00e9v\u0151, az MG63 osteog\u00e9n differenci\u00e1l\u00f3d\u00e1s\u00e1t el\u0151seg\u00edt\u0151 hat\u00f3anyagok vizsg\u00e1lat\u00e1hoz spektr\u00e1lis korrel\u00e1ci\u00f3s elemz\u00e9st v\u00e9gezt\u00fcnk az ALP-aktivit\u00e1s \u00e9s az ujjlenyomat-spektrumok \u00e1ltal kalibr\u00e1lt jellegzetes cs\u00facsok k\u00f6z\u00f6tt. A csontt\u00f6red\u00e9kfolt ujjlenyomat-spektrum\u00e1nak jellegzetes cs\u00facsai \u00e9s az ALP-aktivit\u00e1s k\u00f6z\u00f6tti spektr\u00e1lis hat\u00e1skapcsolat \u00e1tfog\u00f3 elemz\u00e9se \u00e9rdek\u00e9ben ez a k\u00eds\u00e9rlet \u00e1tfog\u00f3an h\u00e1rom m\u00f3dszert alkalmazott: sz\u00fcrke korrel\u00e1ci\u00f3s elemz\u00e9s, k\u00e9tv\u00e1ltoz\u00f3s korrel\u00e1ci\u00f3s elemz\u00e9s \u00e9s legkisebb n\u00e9gyzetek regresszi\u00f3s elemz\u00e9se. Meg\u00e1llap\u00edtottuk, hogy a 4. cs\u00facs, az 5. cs\u00facs \u00e9s a 12. cs\u00facs magas korrel\u00e1ci\u00f3t mutat az ALP-aktivit\u00e1ssal, \u00e9s pozit\u00edvan korrel\u00e1lnak, a legnagyobb m\u00e9rt\u00e9kben j\u00e1rulnak hozz\u00e1 az ALP-aktivit\u00e1shoz, \u00e9s fontos v\u00e1ltoz\u00f3k, amelyek befoly\u00e1solj\u00e1k az ALP-aktivit\u00e1st.
\nAz UPLC-Q-TOF\/MS technol\u00f3gia jellemz\u0151i az er\u0151s szelektivit\u00e1s, a nagy \u00e9rz\u00e9kenys\u00e9g, az egyszer\u0171 minta-el\u0151kezel\u00e9s, a nagy pontoss\u00e1g \u00e9s a nagy felbont\u00e1s, amelyekkel a csontt\u00f6red\u00e9kek k\u00e9miai \u00f6sszetev\u0151i \u00e1tfog\u00f3an \u00e9s gyorsan azonos\u00edthat\u00f3k. Ebben a tanulm\u00e1nyban az UPLC-Q-TOF\/MS-t negat\u00edv ion m\u00f3dban haszn\u00e1lt\u00e1k a csontt\u00f6red\u00e9k-tonikumok 40 komponens\u00e9nek azonos\u00edt\u00e1s\u00e1ra. Az azonos\u00edtott komponens, amely jelent\u0151sen hozz\u00e1j\u00e1rul az ALP-aktivit\u00e1shoz, a 4. cs\u00facs k\u00e1v\u00e9sav-4-O - \u03b2 - D-gl\u00fckopiranozid; 5. cs\u00facs katechin-7-gl\u00fckozid; 12. cs\u00facs naringin \u00e9s aktivit\u00e1sa valid\u00e1l\u00e1sra ker\u00fclt. A naringin egy flavonoid vegy\u00fclet, \u00e9s a modern farmakol\u00f3giai kutat\u00e1sok kimutatt\u00e1k, hogy a naringin k\u00fcl\u00f6nb\u00f6z\u0151 betegs\u00e9gek kezel\u00e9s\u00e9re vagy megel\u0151z\u00e9s\u00e9re haszn\u00e1lhat\u00f3, p\u00e9ld\u00e1ul csontritkul\u00e1s, antioxid\u00e1ns, daganatellenes \u00e9s a sz\u00edvizomk\u00e1rosod\u00e1s jav\u00edt\u00e1s\u00e1ra. A megl\u00e9v\u0151 kutat\u00e1sok azt is jelzik, hogy a naringin fontos hat\u00f3anyag a csontt\u00f6r\u00e9s elleni tonik\u00e1kban. A k\u00e1v\u00e9sav-4-O - \u03b2 - D-gl\u00fckopiranozid \u00e9s a katechin-7-gl\u00fckozid farmakol\u00f3giai tev\u00e9kenys\u00e9g\u00e9r\u0151l m\u00e9g nem sz\u00e1moltak be, \u00e9s tov\u00e1bbi kutat\u00e1sok indokoltak. E tanulm\u00e1ny eredm\u00e9nyei bizonyos referencia jelent\u0151s\u00e9ggel b\u00edrnak a csontt\u00f6rmel\u00e9k-tonikumok min\u0151s\u00e9gellen\u0151rz\u00e9se \u00e9s farmakol\u00f3giai kutat\u00e1sa szempontj\u00e1b\u00f3l.<\/p>","protected":false},"excerpt":{"rendered":"

Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 Gu Duan Bu is the dried rhizome of Drynaria fortunei (Kunze) J. Sm., a water dragon orthopedic plant. It is warm in nature, bitter in taste, and belongs to the liver and kidney […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nStudy on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/rhizoma-drynariae\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 Gu Duan Bu is the dried rhizome of Drynaria fortunei (Kunze) J. Sm., a water dragon orthopedic plant. It is warm in nature, bitter in taste, and belongs to the liver and kidney […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/longchangextracts.com\/hu\/rhizoma-drynariae\/\" \/>\n<meta property=\"og:site_name\" content=\"China Chemical Manufacturer\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-04T14:37:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png\" \/>\n<meta name=\"author\" content=\"longcha9\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szerz\u0151:\" \/>\n\t<meta name=\"twitter:data1\" content=\"longcha9\" \/>\n\t<meta name=\"twitter:label2\" content=\"Becs\u00fclt olvas\u00e1si id\u0151\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 perc\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/\",\"url\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/\",\"name\":\"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 - China Chemical Manufacturer\",\"isPartOf\":{\"@id\":\"https:\/\/longchangextracts.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png\",\"datePublished\":\"2024-08-04T14:37:37+00:00\",\"dateModified\":\"2024-08-04T14:37:37+00:00\",\"author\":{\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\"},\"breadcrumb\":{\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#breadcrumb\"},\"inLanguage\":\"hu\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage\",\"url\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png\",\"contentUrl\":\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/longchangextracts.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/longchangextracts.com\/#website\",\"url\":\"https:\/\/longchangextracts.com\/\",\"name\":\"China Chemical Manufacturer\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/longchangextracts.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"hu\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869\",\"name\":\"longcha9\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"hu\",\"@id\":\"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g\",\"caption\":\"longcha9\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tanulm\u00e1ny a spektr\u00e1lis hat\u00e1s k\u00f6z\u00f6tti kapcsolat UPLC ujjlenyomat csontt\u00f6red\u00e9k folt \u00e9s az alkalikus foszfat\u00e1z aktivit\u00e1s emberi osteosarcoma sejt MG63 - K\u00edna K\u00e9miai Gy\u00e1rt\u00f3","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/longchangextracts.com\/hu\/rhizoma-drynariae\/","og_locale":"hu_HU","og_type":"article","og_title":"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 - China Chemical Manufacturer","og_description":"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63 Gu Duan Bu is the dried rhizome of Drynaria fortunei (Kunze) J. Sm., a water dragon orthopedic plant. It is warm in nature, bitter in taste, and belongs to the liver and kidney […]","og_url":"https:\/\/longchangextracts.com\/hu\/rhizoma-drynariae\/","og_site_name":"China Chemical Manufacturer","article_published_time":"2024-08-04T14:37:37+00:00","og_image":[{"url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png"}],"author":"longcha9","twitter_card":"summary_large_image","twitter_misc":{"Szerz\u0151:":"longcha9","Becs\u00fclt olvas\u00e1si id\u0151":"6 perc"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/","url":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/","name":"Tanulm\u00e1ny a spektr\u00e1lis hat\u00e1s k\u00f6z\u00f6tti kapcsolat UPLC ujjlenyomat csontt\u00f6red\u00e9k folt \u00e9s az alkalikus foszfat\u00e1z aktivit\u00e1s emberi osteosarcoma sejt MG63 - K\u00edna K\u00e9miai Gy\u00e1rt\u00f3","isPartOf":{"@id":"https:\/\/longchangextracts.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage"},"image":{"@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage"},"thumbnailUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png","datePublished":"2024-08-04T14:37:37+00:00","dateModified":"2024-08-04T14:37:37+00:00","author":{"@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869"},"breadcrumb":{"@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#breadcrumb"},"inLanguage":"hu","potentialAction":[{"@type":"ReadAction","target":["https:\/\/longchangextracts.com\/rhizoma-drynariae\/"]}]},{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#primaryimage","url":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png","contentUrl":"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-68.png"},{"@type":"BreadcrumbList","@id":"https:\/\/longchangextracts.com\/rhizoma-drynariae\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/longchangextracts.com\/"},{"@type":"ListItem","position":2,"name":"Study on the spectral effect relationship between UPLC fingerprint of bone fragment patch and alkaline phosphatase activity in human osteosarcoma cell MG63"}]},{"@type":"WebSite","@id":"https:\/\/longchangextracts.com\/#website","url":"https:\/\/longchangextracts.com\/","name":"K\u00edna Vegyi Gy\u00e1rt\u00f3","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/longchangextracts.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"hu"},{"@type":"Person","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/80933ac6926ad63fea74ec33f8d04869","name":"longcha9","image":{"@type":"ImageObject","inLanguage":"hu","@id":"https:\/\/longchangextracts.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c1e84ee0759373263198c58e8f338f80?s=96&d=mm&r=g","caption":"longcha9"}}]}},"_links":{"self":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/4507"}],"collection":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/comments?post=4507"}],"version-history":[{"count":1,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/4507\/revisions"}],"predecessor-version":[{"id":4522,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/posts\/4507\/revisions\/4522"}],"wp:attachment":[{"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/media?parent=4507"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/categories?post=4507"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/longchangextracts.com\/hu\/wp-json\/wp\/v2\/tags?post=4507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}