{"id":3852,"date":"2024-08-03T08:22:31","date_gmt":"2024-08-03T08:22:31","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=3852"},"modified":"2024-08-03T08:22:31","modified_gmt":"2024-08-03T08:22:31","slug":"fermentation-broth-of-guantu-sporangium","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/fermentation-broth-of-guantu-sporangium\/","title":{"rendered":"A Guantu San Nang bakt\u00e9riumok ferment\u00e1ci\u00f3s leves\u00e9nek hat\u00e1sa az elh\u00edz\u00e1sra \u00e9s a b\u00e9l mikrobi\u00f3t\u00e1ra magas zs\u00edrtartalm\u00fa \u00e9trend\u0171 patk\u00e1nyokn\u00e1l"},"content":{"rendered":"

A Guantu San Nang bakt\u00e9riumok ferment\u00e1ci\u00f3s leves\u00e9nek hat\u00e1sa az elh\u00edz\u00e1sra \u00e9s a b\u00e9l mikrobi\u00f3t\u00e1ra magas zs\u00edrtartalm\u00fa \u00e9trend\u0171 patk\u00e1nyokn\u00e1l
\nAz elh\u00edz\u00e1s a szervezetben a zs\u00edr t\u00falzott felhalmoz\u00f3d\u00e1s\u00e1ra utal, ami a rendellenes energia-anyagcser\u00e9nek k\u00f6sz\u00f6nhet\u0151. A magas zs\u00edr- \u00e9s cukortartalm\u00fa \u00e9trend napjainkban a legelterjedtebb di\u00e9t\u00e1s \u00e9trendd\u00e9 v\u00e1lt a vil\u00e1gon. A magas zs\u00edr- \u00e9s cukortartalm\u00fa \u00f6sszetev\u0151k t\u00falzott bevitele zs\u00edrfelhalmoz\u00f3d\u00e1shoz \u00e9s elh\u00edz\u00e1shoz vezet. A t\u00falzott elh\u00edz\u00e1s nemcsak az emberek ment\u00e1lis eg\u00e9szs\u00e9g\u00e9re van hat\u00e1ssal, hanem sz\u00e1mos anyagcsere-betegs\u00e9ghez is vezethet, mint p\u00e9ld\u00e1ul cukorbetegs\u00e9g, sz\u00edv- \u00e9s \u00e9rrendszeri betegs\u00e9gek, hiperlipid\u00e9mia, magas v\u00e9rnyom\u00e1s \u00e9s \u00edgy tov\u00e1bb. Az elh\u00edz\u00e1s glob\u00e1lis k\u00f6zeg\u00e9szs\u00e9g\u00fcgyi probl\u00e9m\u00e1v\u00e1 v\u00e1lt, \u00e9s komoly vesz\u00e9lyt jelent az emberi eg\u00e9szs\u00e9gre. A b\u00e9lmikrobi\u00f3ta a gazdaszervezet b\u00e9lrendszer\u00e9ben \u00e9l\u0151 nagy mikrobi\u00e1lis k\u00f6z\u00f6ss\u00e9g, amely els\u0151sorban a szervezeten bel\u00fcli homeoszt\u00e1zis fenntart\u00e1s\u00e1\u00e9rt felel\u0151s. Kutat\u00e1sok kimutatt\u00e1k, hogy a b\u00e9lmikrobi\u00f3ta hat\u00e9konyan szab\u00e1lyozza a szervezet anyagcser\u00e9j\u00e9t \u00e9s energiaegyens\u00faly\u00e1t, \u00e9s d\u00f6nt\u0151 szerepet j\u00e1tszik az elh\u00edz\u00e1s kialakul\u00e1s\u00e1nak \u00e9s fejl\u0151d\u00e9s\u00e9nek megel\u0151z\u00e9s\u00e9ben.
\nAz Eurotium cristatum, m\u00e1s n\u00e9ven \"arany vir\u00e1ggomba\", az Ascomycota rendbe, az Aspergillus csal\u00e1dba \u00e9s az Ascomycota nemzets\u00e9gbe tartoz\u00f3 potenci\u00e1lis probiotikus gomba. A hagyom\u00e1nyos Fuzhuan tea \"vir\u00e1gz\u00e1si\" folyamat\u00e1ban kulcsfontoss\u00e1g\u00fa mikroorganizmus. A ferment\u00e1ci\u00f3s folyamat sor\u00e1n a Guantu San Nang bakt\u00e9riumok k\u00fcl\u00f6nb\u00f6z\u0151 bioakt\u00edv anyagcsereterm\u00e9keket, p\u00e9ld\u00e1ul flavonoidokat, alkaloidokat, piperazindion-sz\u00e1rmaz\u00e9kokat \u00e9s gombapoliszacharidokat k\u00e9pesek el\u0151\u00e1ll\u00edtani, amelyek lipidcs\u00f6kkent\u0151 \u00e9s tests\u00falycs\u00f6kkent\u0151, b\u00e9lmikrobi\u00f3ta-szab\u00e1lyoz\u00f3 \u00e9s bakt\u00e9riumg\u00e1tl\u00f3 hat\u00e1s\u00faak, hat\u00e9konyan szab\u00e1lyozva az emberi anyagcser\u00e9t. A Guantu sporangiumot sz\u00e9les k\u00f6rben haszn\u00e1lj\u00e1k az \u00e9lelmiszerek \u00e9s a hagyom\u00e1nyos k\u00ednai orvosl\u00e1s ferment\u00e1ci\u00f3s ter\u00fcletein. Mint biztons\u00e1gos \u00e9s k\u00f6rnyezetbar\u00e1t probiotikus gomba, a Candida albicans nemcsak a szubsztr\u00e1t \u00edz\u00e9t jav\u00edtja, hanem biol\u00f3giai aktivit\u00e1ssal is rendelkezik, mint p\u00e9ld\u00e1ul koleszterinszint-cs\u00f6kkent\u0151, antioxid\u00e1ns \u00e9s v\u00e9rcukorszint-cs\u00f6kkent\u0151. Sz\u00e1mos tanulm\u00e1ny azt is kimutatta, hogy a Streptococcus pneumoniae intracellul\u00e1ris \u00e9s extracellul\u00e1ris poliszacharidjai a b\u00e9l mikrobi\u00f3ta szab\u00e1lyoz\u00e1s\u00e1val \u00e9s a b\u00e9lg\u00e1t jav\u00edt\u00e1s\u00e1val n\u00f6velhetik a szervezet immunfunkci\u00f3j\u00e1t, valamint j\u00f3 lipidcs\u00f6kkent\u0151 \u00e9s fogy\u00f3k\u00far\u00e1s hat\u00e1ssal rendelkeznek. Jelenleg a Colletotrichum coronatum ferment\u00e1ci\u00f3s folyamata f\u0151k\u00e9nt szil\u00e1rd form\u00e1ban t\u00f6rt\u00e9nik, kevesebb foly\u00e9kony form\u00e1ban. E tanulm\u00e1ny c\u00e9lja, hogy a Colletotrichum coronatum ferment\u00e1ci\u00f3s leves\u00e9t foly\u00e9kony teny\u00e9szt\u00e9si m\u00f3dszerrel nyerje. Ezzel egyidej\u0171leg egy \u00e9lelmiszerrel terjed\u0151 elh\u00edzott patk\u00e1nymodellt hoztunk l\u00e9tre, hogy megvizsg\u00e1ljuk a Streptococcus pneumoniae ferment\u00e1ci\u00f3s leves\u00e9nek hat\u00e1s\u00e1t az elh\u00edzott patk\u00e1nyok anyagcser\u00e9j\u00e9re \u00e9s b\u00e9lmikrobi\u00f3ta-rendelleness\u00e9geire.<\/p>\n

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\nAz elh\u00edz\u00e1s sz\u00e1mos eg\u00e9szs\u00e9g\u00fcgyi probl\u00e9m\u00e1val j\u00e1r\u00f3 betegs\u00e9g, amelyet sz\u00e9les k\u00f6rben \u00fagy v\u00e9lik, hogy a kevesebb fizikai er\u0151fesz\u00edt\u00e9s \u00e9s a magas kal\u00f3riabevitel okozza, \u00e9s szorosan \u00f6sszef\u00fcgg a szervezetben l\u00e9v\u0151 kr\u00f3nikus \u00e9s alacsony fok\u00fa gyullad\u00e1ssal. A vizsg\u00e1lat eredm\u00e9nyei azt mutatt\u00e1k, hogy a magas zs\u00edrtartalm\u00fa \u00e9trend jelent\u0151sen megn\u00f6velte a patk\u00e1nyok tests\u00faly\u00e1t \u00e9s zs\u00edrlerak\u00f3d\u00e1s\u00e1t, s\u00falyosb\u00edtva az anyagcserezavarokat. A Candida albicans n\u00f6veked\u00e9si id\u0151szaka alatt k\u00fcl\u00f6nb\u00f6z\u0151 hasznos anyagcsereterm\u00e9kek termel\u0151dhetnek, p\u00e9ld\u00e1ul olyan gombapoliszacharidok, mint a ramn\u00f3z \u00e9s a galakt\u00f3z, amelyek er\u0151s g\u00e1tl\u00f3 hat\u00e1ssal vannak az elh\u00edz\u00e1sra, \u00e9s bizonyos szab\u00e1lyoz\u00f3 hat\u00e1ssal vannak az elh\u00edzott egerek v\u00e9rzs\u00edrszintj\u00e9re. A tanulm\u00e1ny azt is meg\u00e1llap\u00edtotta, hogy a Colletotrichum coronatum ferment\u00e1lt kivonata tov\u00e1bb szab\u00e1lyozhatja a m\u00e1jgyullad\u00e1st \u00e9s az \u00e9lelmiszer okozta elh\u00edz\u00e1s okozta zs\u00edrfelhalmoz\u00f3d\u00e1st az\u00e1ltal, hogy modul\u00e1lja a m\u00e1jban az IL-6\/STAT3 jel\u00e1tviteli \u00fatvonalat. A k\u00eds\u00e9rlet azt is kimutatta, hogy a Candida albicans ferment\u00e1ci\u00f3s leve g\u00e1tl\u00f3 hat\u00e1ssal van az \u00e9trend \u00e1ltal kiv\u00e1ltott elh\u00edz\u00e1s szintj\u00e9re, k\u00fcl\u00f6nb\u00f6z\u0151 m\u00e9rt\u00e9kben enyh\u00edti a zs\u00edrfelhalmoz\u00f3d\u00e1st, \u00e9s cs\u00f6kkenti a TG, TC \u00e9s LDH-C szintj\u00e9t a patk\u00e1nysz\u00e9rumban, ami seg\u00edt szab\u00e1lyozni a koleszterin metabolikus egyens\u00faly\u00e1t. Az LDH-C szintje a sz\u00e9rumban az ateroszkler\u00f3zis egyik kock\u00e1zati t\u00e9nyez\u0151je. A lipidperoxid\u00e1ci\u00f3 szint\u00e9n \u00f6sszef\u00fcgg az ateroszkler\u00f3zis megjelen\u00e9s\u00e9vel \u00e9s kialakul\u00e1s\u00e1val. Ez\u00e9rt a Sarcocystis coronarius ferment\u00e1ci\u00f3s folyad\u00e9k nemcsak a magas zs\u00edrtartalm\u00fa \u00e9trend \u00e1ltal kiv\u00e1ltott anyagcserezavart tudja hat\u00e9konyan szab\u00e1lyozni, hanem az ateroszkler\u00f3zist is megel\u0151zheti.
\nA b\u00e9lmikrobi\u00f3ta diverzit\u00e1s\u00e1nak cs\u00f6kken\u00e9se az elh\u00edz\u00e1s magas kock\u00e1zati t\u00e9nyez\u0151je. A 16S rDNS-amplifik\u00e1ci\u00f3s szekven\u00e1l\u00e1si technol\u00f3gi\u00e1val v\u00e9gzett elemz\u00e9s kimutatta, hogy a magas zs\u00edrtartalm\u00fa \u00e9trend indukci\u00f3ja mellett a patk\u00e1nyok b\u00e9lmikrobi\u00f3t\u00e1j\u00e1nak diverzit\u00e1sa jelent\u0151sen cs\u00f6kkent, \u00e9s az F\/B ar\u00e1ny is jelent\u0151sen cs\u00f6kkent. Ez az eredm\u00e9ny \u00f6sszhangban van Lin, Zhang \u00e9s m\u00e1sok kutat\u00e1s\u00e1val, miszerint a b\u00e9lben az F\/B ar\u00e1ny kiegyens\u00falyozatlans\u00e1ga el\u0151seg\u00edti a gazdaszervezet elh\u00edz\u00e1s\u00e1nak kialakul\u00e1s\u00e1t. A Firmicutes b\u0151s\u00e9g\u00e9nek cs\u00f6kken\u00e9se a magasabb poliszacharidtartalm\u00fa \u00e9trenddel \u00e9s a lipopoliszacharidok termel\u00e9s\u00e9vel f\u00fcgg \u00f6ssze. A Guantu San Nang bakt\u00e9riumok ferment\u00e1ci\u00f3s leves\u00e9vel t\u00f6rt\u00e9n\u0151 beavatkoz\u00e1s ut\u00e1n az F\/B ar\u00e1ny felszab\u00e1lyoz\u00f3dott, \u00e9s a mikrobi\u00f3ta diverzit\u00e1sa helyre\u00e1llt, hat\u00e9konyan jav\u00edtva a zs\u00edrbevitel okozta b\u00e9lmikrobi\u00f3ta egyens\u00falyhi\u00e1nyt. Vannak tanulm\u00e1nyok, amelyek szerint a Helicobacter pylori egy ismert j\u00f3t\u00e9kony bakt\u00e9rium a b\u00e9lben, \u00e9s arr\u00f3l is besz\u00e1moltak, hogy az NK4A214_csoport abundanci\u00e1j\u00e1nak n\u00f6veked\u00e9se n\u00f6veli az antimikrobi\u00e1lis peptidek felszabadul\u00e1s\u00e1t a b\u00e9lben, fokozva annak v\u00e9delmi \u00e9s v\u00e9d\u0151 funkci\u00f3it. A Christensennellacee_R-7 csoport egy potenci\u00e1lis probiotikum, amely sz\u00e9les k\u00f6rben jelen van a b\u00e9lben \u00e9s a ny\u00e1lkah\u00e1rty\u00e1ban, \u00e9s amely k\u00e9pes a pro-inflammatorikus citokineket lefel\u00e9 szab\u00e1lyozni \u00e9s jav\u00edtani a b\u00e9lny\u00e1lkah\u00e1rtya barrier funkci\u00f3j\u00e1t. Ezek a b\u00e9lny\u00e1lkah\u00e1rty\u00e1hoz kapcsol\u00f3d\u00f3 mikroorganizmusok a b\u00e9lgyullad\u00e1s \u00e9s a b\u00e9lny\u00e1lkah\u00e1rtya-barrier zavar\u00e1nak cs\u00f6kkent\u00e9s\u00e9vel fejthetik ki elh\u00edz\u00e1sellenes hat\u00e1sukat. A Lactobacillus a nagy d\u00f3zis\u00fa csoport egyik jellegzetes mikrobi\u00f3t\u00e1ja \u00e9s a legfontosabb probiotikum az emberi \u00e9s \u00e1llati b\u00e9lmikrobi\u00f3t\u00e1ban. Bizony\u00edtottan enyh\u00edti a magas zs\u00edrtartalm\u00fa \u00e9trend \u00e1ltal okozott elh\u00edz\u00e1st emberekben \u00e9s \u00e1llatokban. A Turicibacter nemzets\u00e9ghez tartoz\u00f3 bakt\u00e9riumok patog\u00e9n \u00e9letm\u00f3dot folytatnak, \u00e9s gyakoris\u00e1guk n\u00f6veked\u00e9se a b\u00e9lmikrobi\u00f3ta szerkezet\u00e9nek zavara egyik jele. Vannak olyan tanulm\u00e1nyok is, amelyek arra utalnak, hogy a Bacteroidetes nemzets\u00e9gben nagysz\u00e1m\u00fa patog\u00e9n bakt\u00e9rium k\u00e9pes ecetsavat termelni. B\u0151s\u00e9g\u00fck n\u00f6veked\u00e9se serkentheti a peroxid\u00e1ci\u00f3s gyullad\u00e1sos faktorok \u00e9s lipidg\u00e1tl\u00f3 faktorok termel\u00e9s\u00e9t a b\u00e9lben, g\u00e1tolhatja a lipidoxid\u00e1ci\u00f3s anyagcser\u00e9t, \u00e9s el\u0151seg\u00edtheti a lipidek felhalmoz\u00f3d\u00e1s\u00e1t a szervezetben. A k\u00f3rokoz\u00f3k feld\u00fasul\u00e1sa a gazdaszervezet sziszt\u00e9m\u00e1s gyullad\u00e1s\u00e1t okozhatja, ami \u00f6sszef\u00fcgg az elh\u00edz\u00e1ssal \u00e9s a kapcsol\u00f3d\u00f3 anyagcserezavarokkal. A Colletotrichum coronatum ferment\u00e1ci\u00f3s leve jav\u00edthatja a magas zs\u00edrtartalm\u00fa \u00e9trend \u00e1ltal okozott elh\u00edz\u00e1st, fokozhatja a b\u00e9l v\u00e9delmi funkci\u00f3j\u00e1t, \u00e9s cs\u00f6kkentheti a gyullad\u00e1st az\u00e1ltal, hogy n\u00f6veli a hasznos bakt\u00e9riumok, p\u00e9ld\u00e1ul az NK4A214_csoport, UCG-005, Christensennellacee_R-7_csoport \u00e9s Lactobacillus b\u0151s\u00e9g\u00e9t a b\u00e9lben, \u00e9s cs\u00f6kkenti a Turicibacter \u00e9s Bacteroides b\u0151s\u00e9g\u00e9t.
\n\u00d6sszefoglalva, az elh\u00edz\u00e1s el\u0151fordul\u00e1sa \u00e9s kialakul\u00e1sa szorosan \u00f6sszef\u00fcgg a b\u00e9lmikrobi\u00f3ta egyens\u00falyhi\u00e1ny\u00e1val. A Guantu San Nang bakt\u00e9riumok ferment\u00e1ci\u00f3s leve hat\u00e9konyan jav\u00edthatja a magas zs\u00edrtartalm\u00fa di\u00e9t\u00e1s patk\u00e1nyok elh\u00edz\u00e1si \u00e1llapot\u00e1t, szab\u00e1lyozhatja a hasznos mikrobi\u00e1lis k\u00f6z\u00f6ss\u00e9gek b\u0151s\u00e9g\u00e9t a gazdaszervezet b\u00e9lrendszer\u00e9ben, kifejtheti j\u00f3t\u00e9kony vitalit\u00e1sukat, \u00e9s cs\u00f6kkentheti a k\u00e1ros mikrobi\u00e1lis k\u00f6z\u00f6ss\u00e9gek b\u0151s\u00e9g\u00e9t, el\u00e9rve a fogy\u00e1s \u00e9s a lipidcs\u00f6kkent\u00e9s hat\u00e1s\u00e1t. A szervezet b\u00e9lmikrobi\u00f3t\u00e1j\u00e1nak szerkezete \u00e9s \u00f6sszet\u00e9tele azonban viszonylag \u00f6sszetett, \u00e9s m\u00e9g tov\u00e1bbi kutat\u00e1sokat ig\u00e9nyelnek azok a specifikus molekul\u00e1ris mechanizmusok, amelyek r\u00e9v\u00e9n a Colletotrichum coronatum ferment\u00e1ci\u00f3s leve szab\u00e1lyozza a b\u00e9lmikrobi\u00f3t\u00e1t, valamint az, hogy mely komponensek rendelkeznek elh\u00edz\u00e1s elleni hat\u00e1ssal.<\/p>","protected":false},"excerpt":{"rendered":"

A Guantu San Nang bakt\u00e9riumok ferment\u00e1ci\u00f3s leves\u00e9nek hat\u00e1sa az elh\u00edz\u00e1sra \u00e9s a b\u00e9l mikrobi\u00f3t\u00e1ra magas zs\u00edrtartalm\u00fa \u00e9trend\u0171 patk\u00e1nyokn\u00e1l Az elh\u00edz\u00e1s a zs\u00edr t\u00falzott felhalmoz\u00f3d\u00e1s\u00e1ra utal a szervezetben a rendellenes energia-anyagcsere miatt. A magas zs\u00edr- \u00e9s cukortartalm\u00fa di\u00e9ta napjainkban a legelterjedtebb di\u00e9t\u00e1s \u00e9trendd\u00e9 v\u00e1lt a vil\u00e1gon. A t\u00falzott bevitel [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nThe effect of fermentation broth of Guantu San Nang bacteria on obesity and intestinal microbiota in high-fat diet rats - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/fermentation-broth-of-guantu-sporangium\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The effect of fermentation broth of Guantu San Nang bacteria on obesity and intestinal microbiota in high-fat diet rats - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"The effect of fermentation broth of Guantu San Nang bacteria on obesity and intestinal microbiota in high-fat diet rats Obesity refers to the excessive accumulation of fat in the body due to abnormal energy metabolism. High fat and high sugar diet has become the most common diet mode in the world today. 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