{"id":3536,"date":"2024-08-02T14:40:15","date_gmt":"2024-08-02T14:40:15","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=3536"},"modified":"2024-08-02T14:40:15","modified_gmt":"2024-08-02T14:40:15","slug":"huaze-lan","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/huaze-lan\/","title":{"rendered":"A Septoriella phragmitis endofita gomba m\u00e1sodlagos anyagcsereterm\u00e9keinek \u00e9s biol\u00f3giai aktivit\u00e1s\u00e1nak vizsg\u00e1lata Huaze Lanban"},"content":{"rendered":"<p>A Septoriella phragmitis endofita gomba m\u00e1sodlagos anyagcsereterm\u00e9keinek \u00e9s biol\u00f3giai aktivit\u00e1s\u00e1nak vizsg\u00e1lata Huaze Lanban<\/p>\n<p>Az endofita gomb\u00e1knak sz\u00e1mos faja l\u00e9tezik, \u00e9s anyagcsereterm\u00e9keik v\u00e1ltozatosak, amelyek a gazdaszervezethez hasonl\u00f3an k\u00fcl\u00f6nb\u00f6z\u0151 hat\u00f3anyagokat termelhetnek. A modern farmakol\u00f3giai vizsg\u00e1latok kimutatt\u00e1k, hogy a Huaze orchide\u00e1b\u00f3l sz\u00e1rmaz\u00f3 Septoriella phragmitis endofita gomba kivonata antidepressz\u00e1ns, gyullad\u00e1scs\u00f6kkent\u0151, immunszab\u00e1lyoz\u00f3 \u00e9s antioxid\u00e1ns hat\u00e1s\u00fa. Zhang \u00e9s munkat\u00e1rsai 8 endofita gomb\u00e1t izol\u00e1ltak a Hua Zelanb\u00f3l, \u00e9s in vitro tumorellenes k\u00eds\u00e9rleteket v\u00e9geztek a ferment\u00e1ci\u00f3s leves\u00fck etil-acet\u00e1t kivonat\u00e1val, de az egyes vegy\u00fcletekre vonatkoz\u00f3 kutat\u00e1sok hi\u00e1nyoztak. A kutat\u00f3csoport egy endofita gomb\u00e1t izol\u00e1lt a Huaze Lan gy\u00f6ker\u00e9b\u0151l, \u00e9s a t\u00f6rzs azonos\u00edt\u00e1sa ut\u00e1n meg\u00e1llap\u00edtott\u00e1k, hogy az k\u00fcl\u00f6nb\u00f6zik a Zhang Jianfen \u00e9s t\u00e1rsai \u00e1ltal izol\u00e1lt endofita gomb\u00e1t\u00f3l, \u00e9s a Septoriella phragmitis. Jelenleg nincs irodalmi adat a m\u00e1sodlagos anyagcsereterm\u00e9keir\u0151l. A Septoriella phragmatis endofita gomba anyagi alapjainak tov\u00e1bbi tanulm\u00e1nyoz\u00e1sa \u00e9rdek\u00e9ben ez a tanulm\u00e1ny izol\u00e1lta \u00e9s azonos\u00edtotta k\u00e9miai komponenseit, valamint tesztelte cukorbetegs\u00e9g- \u00e9s daganatellenes aktivit\u00e1s\u00e1t, referenci\u00e1t szolg\u00e1ltatva egy rendk\u00edv\u00fcl hat\u00e9kony \u00e9s alacsony toxikus cukorbetegs\u00e9g-ellenes vezet\u0151 vegy\u00fclet megtal\u00e1l\u00e1s\u00e1hoz, valamint e gy\u00f3gygomba-forr\u00e1s fejleszt\u00e9s\u00e9hez \u00e9s felhaszn\u00e1l\u00e1s\u00e1hoz.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone  wp-image-3539\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/640.jpg\" alt=\"\" width=\"700\" height=\"324\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/640.jpg 854w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/640-768x355.jpg 768w\" sizes=\"(max-width: 700px) 100vw, 700px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-3540\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/640.webp\" alt=\"\" width=\"472\" height=\"364\" \/>Ez a tanulm\u00e1ny felt\u00e1rta a t\u00f6rzs k\u00e9miai \u00f6sszet\u00e9tel\u00e9t, \u00e9s 10 vegy\u00fcletet, k\u00f6zt\u00fck 5 alkaloid\u00e1t, 4 fenolt \u00e9s 1 benzofur\u00e1nt nyert, amelyeket mind el\u0151sz\u00f6r izol\u00e1ltak a t\u00f6rzsb\u0151l. Emellett el\u0151sz\u00f6r fedezt\u00e9k fel, hogy a mikroorganizmusok k\u00e9pesek el\u0151\u00e1ll\u00edtani az Eupatorium adenophorum n\u00f6v\u00e9ny hat\u00f3anyag\u00e1t, a puerarint. A farmakol\u00f3giai aktivit\u00e1si vizsg\u00e1latok eredm\u00e9nyei azt mutatt\u00e1k, hogy a 6. \u00e9s 7. vegy\u00fclet j\u00f3 g\u00e1tl\u00f3 aktivit\u00e1st mutat az alfa-gl\u00fckozid\u00e1zzal szemben; a 6., 7. \u00e9s 9. vegy\u00fcletek j\u00f3 PTP1B g\u00e1tl\u00f3 aktivit\u00e1st mutatnak, \u00e9s aktivit\u00e1suk jobb, mint a pozit\u00edv hat\u00f3anyag\u00fa n\u00e1trium-ortovanad\u00e1t\u00e9; az 5. \u00e9s 6. vegy\u00fcletek a t\u00f6bbi vegy\u00fclethez k\u00e9pest bizonyos g\u00e1tl\u00f3 aktivit\u00e1st mutatnak a HGC-27 gyomorr\u00e1kos sejtvonallal szemben. Tov\u00e1bbi molekul\u00e1ris dokkol\u00e1si k\u00eds\u00e9rletek azt mutatt\u00e1k, hogy a 6. \u00e9s 7. vegy\u00fcletek k\u00fcl\u00f6nb\u00f6z\u0151 k\u00f6lcs\u00f6nhat\u00e1sok, p\u00e9ld\u00e1ul hidrog\u00e9nk\u00f6t\u00e9s, hidrof\u00f3bit\u00e1s, konjug\u00e1ci\u00f3 stb. r\u00e9v\u00e9n k\u00f6lcs\u00f6nhat\u00e1sba l\u00e9phetnek az \u03b1 - gl\u00fckozid\u00e1z vagy a PTP1B c\u00e9lfeh\u00e9rj\u00e9k aminosav-maradv\u00e1nyaival. Jelenleg a Septoriella phragmatis gomba m\u00e1sodlagos metabolitjair\u00f3l m\u00e9g nem sz\u00e1moltak be az irodalomban. Ebben a tanulm\u00e1nyban sz\u00e1moltak be el\u0151sz\u00f6r e t\u00f6rzs m\u00e1sodlagos metabolitjair\u00f3l, \u00e9s a tal\u00e1lt vegy\u00fcletek n\u00e9melyike kett\u0151s c\u00e9lpont\u00fa g\u00e1tl\u00f3 hat\u00e1ssal rendelkezik a cukorbetegs\u00e9g ellen. A kutat\u00e1si eredm\u00e9nyeket a Natural Product Research and Development c\u00edm\u0171 foly\u00f3irat 2024. \u00e9vi 6. sz\u00e1m\u00e1ban tett\u00e9k k\u00f6zz\u00e9.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>Study on the secondary metabolites and biological activities of the endophytic fungus Septoriella phragmitis in Huaze Lan There are abundant species of endophytic fungi, and their metabolites are diverse, which may produce various active substances similar to those of the host. Modern pharmacological studies have shown that the extract of the endophytic fungus Septoriella phragmitis [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Study on the secondary metabolites and biological activities of the endophytic fungus Septoriella phragmitis in Huaze Lan - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/huaze-lan\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the secondary metabolites and biological activities of the endophytic fungus Septoriella phragmitis in Huaze Lan - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the secondary metabolites and biological activities of the endophytic fungus Septoriella phragmitis in Huaze Lan There are abundant species of endophytic fungi, and their metabolites are diverse, which may produce various active substances similar to those of the host. 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