{"id":10599,"date":"2026-03-07T23:17:04","date_gmt":"2026-03-07T23:17:04","guid":{"rendered":"https:\/\/longchangextracts.com\/clopidogrel-cas-113665-84-2\/"},"modified":"2026-03-07T23:17:04","modified_gmt":"2026-03-07T23:17:04","slug":"clopidogrel-cas-113665-84-2","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/clopidogrel-cas-113665-84-2\/","title":{"rendered":"Klopidogr\u00e9l (CAS-sz\u00e1m: 113665-84-2)"},"content":{"rendered":"<h1>Klopidogr\u00e9l (CAS-sz\u00e1m: 113665-84-2)<\/h1>\n<h2>Mi az a klopidogr\u00e9l?<\/h2>\n<p>A klopidogr\u00e9l a tienopiridin-csoportba tartoz\u00f3, er\u0151s v\u00e9rlemezke-g\u00e1tl\u00f3 szer. Kereskedelmi nev\u00e9n Plavix n\u00e9ven sz\u00e9les k\u00f6rben alkalmazz\u00e1k a v\u00e9rr\u00f6gk\u00e9pz\u0151d\u00e9s megel\u0151z\u00e9s\u00e9re sz\u00edv- \u00e9s \u00e9rrendszeri betegs\u00e9gben szenved\u0151 betegekn\u00e9l. El\u0151gy\u00f3gyszerk\u00e9nt a klopidogr\u00e9lnek a m\u00e1jban metabolikus aktiv\u00e1l\u00e1sra van sz\u00fcks\u00e9ge ahhoz, hogy v\u00e9rlemezke-g\u00e1tl\u00f3 hat\u00e1s\u00e1t kifejthesse. A vegy\u00fcletet egy t\u00f6bb l\u00e9p\u00e9sb\u0151l \u00e1ll\u00f3 folyamat sor\u00e1n \u00e1ll\u00edtj\u00e1k el\u0151, amely mag\u00e1ban foglalja az optikai szepar\u00e1ci\u00f3t is az akt\u00edv S-enantiomer el\u0151\u00e1ll\u00edt\u00e1sa \u00e9rdek\u00e9ben.<\/p>\n<h2>Milyen el\u0151nyei vannak?<\/h2>\n<h3>A sz\u00edv- \u00e9s \u00e9rrendszeri esem\u00e9nyek megel\u0151z\u00e9se<\/h3>\n<p>A klopidogr\u00e9l jelent\u0151sen cs\u00f6kkenti a sz\u00edvroham, a stroke \u00e9s egy\u00e9b kardiovaszkul\u00e1ris esem\u00e9nyek kock\u00e1zat\u00e1t a magas kock\u00e1zat\u00fa betegekn\u00e9l. K\u00fcl\u00f6n\u00f6sen hat\u00e9kony az akut koron\u00e1ria szindr\u00f3m\u00e1ban (ACS) szenved\u0151 betegek, a kor\u00e1bban sz\u00edvrohamot \u00e1t\u00e9lt betegek, valamint a perif\u00e9ri\u00e1s \u00e9rbetegs\u00e9gben szenved\u0151 betegek eset\u00e9ben.<\/p>\n<h3>Kiv\u00e1l\u00f3 biztons\u00e1gi profil<\/h3>\n<p>M\u00e1s v\u00e9rlemezke-g\u00e1tl\u00f3 szerekhez \u2013 p\u00e9ld\u00e1ul a tiklopidinhez \u2013 k\u00e9pest a klopidogr\u00e9l kevesebb mell\u00e9khat\u00e1st okoz, k\u00fcl\u00f6n\u00f6sen a csontvel\u0151-elnyom\u00e1s el\u0151fordul\u00e1sa alacsonyabb a szok\u00e1sos adagol\u00e1s mellett. Ez\u00e9rt ez a gy\u00f3gyszer az els\u0151dleges v\u00e1laszt\u00e1s a hossz\u00fa t\u00e1v\u00fa v\u00e9rlemezke-g\u00e1tl\u00f3 kezel\u00e9s sor\u00e1n.<\/p>\n<h3>Bizony\u00edtott hat\u00e9konys\u00e1g<\/h3>\n<p>Kiterjedt klinikai vizsg\u00e1latok igazolt\u00e1k a klopidogr\u00e9l hat\u00e9konys\u00e1g\u00e1t a trombotikus esem\u00e9nyek cs\u00f6kkent\u00e9s\u00e9ben. A gy\u00f3gyszer a v\u00e9rlemezk\u00e9k P2Y12 ADP-receptor\u00e1nak visszaford\u00edthatatlan g\u00e1tl\u00e1s\u00e1val fejti ki hat\u00e1s\u00e1t, megakad\u00e1lyozva ezzel a v\u00e9rlemezk\u00e9k \u00f6sszecsapz\u00f3d\u00e1s\u00e1t \u00e9s a v\u00e9rr\u00f6gk\u00e9pz\u0151d\u00e9st.<\/p>\n<h2>Milyen felhaszn\u00e1l\u00e1si ter\u00fcletei vannak?<\/h2>\n<p>A klopidogr\u00e9l a k\u00f6vetkez\u0151 betegs\u00e9gek eset\u00e9n javallott:<\/p>\n<ul>\n<li><strong>Akut koron\u00e1ria szindr\u00f3ma (ACS):<\/strong> ST-emelked\u00e9s n\u00e9lk\u00fcli akut koron\u00e1ria szindr\u00f3m\u00e1ban \u00e9s ST-emelked\u00e9ses miokardi\u00e1lis infarktusban szenved\u0151 betegekn\u00e9l alkalmazz\u00e1k<\/li>\n<li><strong>M\u00e1sodlagos megel\u0151z\u00e9s:<\/strong> Megel\u0151zi a visszat\u00e9r\u0151 sz\u00edvrohamot \u00e9s a stroke-ot azokn\u00e1l a betegekn\u00e9l, akiknek kardiovaszkul\u00e1ris esem\u00e9nyek szerepelnek a k\u00f3rt\u00f6rt\u00e9net\u00e9ben<\/li>\n<li><strong>Perif\u00e9ri\u00e1s \u00e9rbetegs\u00e9g:<\/strong> Cs\u00f6kkenti a tromb\u00f3zisos esem\u00e9nyek el\u0151fordul\u00e1s\u00e1t a perif\u00e9ri\u00e1s art\u00e9ri\u00e1s betegs\u00e9gben szenved\u0151 betegekn\u00e9l<\/li>\n<li><strong>Koron\u00e1ria\u00e9r-betegs\u00e9g:<\/strong> Olyan betegekn\u00e9l alkalmazz\u00e1k, akikn\u00e9l perkut\u00e1n koron\u00e1ria beavatkoz\u00e1st (PCI) v\u00e9geznek sztent be\u00fcltet\u00e9ssel<\/li>\n<li><strong>Agy\u00e9rrendszeri betegs\u00e9g:<\/strong> Seg\u00edt megel\u0151zni az ischaemi\u00e1s stroke kialakul\u00e1s\u00e1t a kock\u00e1zatnak kitett betegekn\u00e9l<\/li>\n<\/ul>\n<h2>Biztons\u00e1g \/ Mell\u00e9khat\u00e1sok<\/h2>\n<p>B\u00e1r a klopidogr\u00e9l \u00e1ltal\u00e1ban j\u00f3l toler\u00e1lhat\u00f3, a betegeknek tiszt\u00e1ban kell lenni\u00fck a lehets\u00e9ges mell\u00e9khat\u00e1sokkal:<\/p>\n<ul>\n<li><strong>Gyakori mell\u00e9khat\u00e1sok:<\/strong> K\u00f6nny\u0171 z\u00faz\u00f3d\u00e1s, fokozott v\u00e9rz\u00e9shajlam, orrv\u00e9rz\u00e9s, fejf\u00e1j\u00e1s<\/li>\n<li><strong>S\u00falyos mell\u00e9khat\u00e1sok:<\/strong> S\u00falyos v\u00e9rz\u00e9s, thrombocytopenia, m\u00e1jfunkci\u00f3s rendelleness\u00e9gek<\/li>\n<li><strong>Gy\u00f3gyszerk\u00f6lcs\u00f6nhat\u00e1sok:<\/strong> K\u00f6lcs\u00f6nhat\u00e1sba l\u00e9phet a nem szteroid gyullad\u00e1scs\u00f6kkent\u0151kkel (NSAID-okkal), a warfarinnal \u00e9s m\u00e1s v\u00e9ralvad\u00e1sg\u00e1tl\u00f3kkal<\/li>\n<li><strong>A CYP2C19 g\u00e9n vari\u00e1ci\u00f3ja:<\/strong> A CYP2C19 g\u00e9n vari\u00e1ns all\u00e9ljeivel rendelkez\u0151 betegekn\u00e9l a gy\u00f3gyszer hat\u00e9konys\u00e1ga cs\u00f6kkenhet<\/li>\n<\/ul>\n<p><strong>Fontos:<\/strong> A betegeknek nem szabad a klopidogr\u00e9l szed\u00e9s\u00e9t az eg\u00e9szs\u00e9g\u00fcgyi szakemberrel val\u00f3 konzult\u00e1ci\u00f3 n\u00e9lk\u00fcl abbahagyniuk, mivel ez n\u00f6velheti a sz\u00edv- \u00e9s \u00e9rrendszeri esem\u00e9nyek kock\u00e1zat\u00e1t.<\/p>\n<h2>K\u00e9miai jellemz\u0151k<\/h2>\n<table>\n<tr>\n<th>Ingatlan<\/th>\n<th>\u00c9rt\u00e9k<\/th>\n<\/tr>\n<tr>\n<td>CAS-sz\u00e1m<\/td>\n<td>113665-84-2<\/td>\n<\/tr>\n<tr>\n<td>Molekul\u00e1ris k\u00e9plet<\/td>\n<td>C16H16ClNO2S<\/td>\n<\/tr>\n<tr>\n<td>Molekulat\u00f6meg<\/td>\n<td>321,8 g\/mol (szabad b\u00e1zis)<\/td>\n<\/tr>\n<tr>\n<td>Megjelen\u00e9s<\/td>\n<td>Feh\u00e9r vagy t\u00f6rtfeh\u00e9r por<\/td>\n<\/tr>\n<tr>\n<td>Gy\u00f3gyszeroszt\u00e1ly<\/td>\n<td>Tienopiridin-alap\u00fa v\u00e9rlemezke-g\u00e1tl\u00f3 szer<\/td>\n<\/tr>\n<tr>\n<td>Term\u00e9kforma<\/td>\n<td>klopidogrel-biszulf\u00e1t<\/td>\n<\/tr>\n<\/table>\n<h2>Gyakran feltett k\u00e9rd\u00e9sek<\/h2>\n<h3>Hogyan hat a klopidogr\u00e9l?<\/h3>\n<p>A klopidogr\u00e9l egy prodrug, amelynek a m\u00e1jban t\u00f6rt\u00e9n\u0151 metabolikus aktiv\u00e1l\u00e1sra van sz\u00fcks\u00e9ge. Akt\u00edv metabolitja visszaford\u00edthatatlanul k\u00f6t\u0151dik a v\u00e9rlemezk\u00e9k P2Y12 ADP-receptor\u00e1hoz, megakad\u00e1lyozva ezzel a v\u00e9rlemezk\u00e9k \u00f6sszecsapz\u00f3d\u00e1s\u00e1t \u00e9s cs\u00f6kkentve a v\u00e9rr\u00f6gk\u00e9pz\u0151d\u00e9s kock\u00e1zat\u00e1t.<\/p>\n<h3>Mennyi id\u0151 alatt fejti ki hat\u00e1s\u00e1t a klopidogr\u00e9l?<\/h3>\n<p>A v\u00e9rlemezke-g\u00e1tl\u00f3 hat\u00e1s a bev\u00e9telt\u0151l sz\u00e1m\u00edtott 2 \u00f3r\u00e1n bel\u00fcl jelentkezik, a v\u00e9rlemezk\u00e9k g\u00e1tl\u00e1s\u00e1nak maxim\u00e1lis m\u00e9rt\u00e9ke pedig a rendszeres adagol\u00e1s megkezd\u00e9s\u00e9t\u0151l sz\u00e1m\u00edtott 3\u20137 napon bel\u00fcl \u00e9rhet\u0151 el.<\/p>\n<h3>A klopidogrel az aszpirinnal egy\u00fctt alkalmazhat\u00f3?<\/h3>\n<p>Igen, a klopidogr\u00e9l \u00e9s az aszpirin kombin\u00e1ci\u00f3j\u00e1b\u00f3l \u00e1ll\u00f3 kett\u0151s v\u00e9rlemezke-g\u00e1tl\u00f3 ter\u00e1pi\u00e1t (DAPT) gyakran \u00edrj\u00e1k fel bizonyos sz\u00edv- \u00e9s \u00e9rrendszeri esem\u00e9nyek vagy beavatkoz\u00e1sok ut\u00e1n, k\u00fcl\u00f6n\u00f6sen sztentbe\u00fcltet\u00e9s ut\u00e1n. Ez a kombin\u00e1ci\u00f3 azonban n\u00f6veli a v\u00e9rz\u00e9s kock\u00e1zat\u00e1t, ez\u00e9rt kiz\u00e1r\u00f3lag orvosi fel\u00fcgyelet mellett alkalmazhat\u00f3.<\/p>\n<h3>Mit tegyek, ha kihagyok egy adagot?<\/h3>\n<p>Ha kihagy egy adag klopidogr\u00e9lt, vegye be, amint esz\u00e9be jut. Ha azonban m\u00e1r k\u00f6zel van a k\u00f6vetkez\u0151 adag bev\u00e9tel\u00e9nek ideje, hagyja ki a kihagyott adagot, \u00e9s folytassa a szok\u00e1sos adagol\u00e1si rendet. Ne vegyen be k\u00e9tszeres adagot.<\/p>\n<h2>Mi\u00e9rt v\u00e1lassza a mi klopidogr\u00e9l\u00fcnket?<\/h2>\n<p>Kiv\u00e1l\u00f3 min\u0151s\u00e9g\u0171 klopidogr\u00e9lt (CAS 113665-84-2) forgalmazunk, amely megfelel a nemzetk\u00f6zi gy\u00f3gyszerk\u00f6nyvi el\u0151\u00edr\u00e1soknak. Term\u00e9k\u00fcnket szigor\u00fa min\u0151s\u00e9g-ellen\u0151rz\u00e9si vizsg\u00e1latoknak vetj\u00fck al\u00e1 a tisztas\u00e1g, a hat\u00e9konys\u00e1g \u00e9s az \u00e1lland\u00f3s\u00e1g biztos\u00edt\u00e1sa \u00e9rdek\u00e9ben. Versenyk\u00e9pes \u00e1rakat \u00e9s megb\u00edzhat\u00f3 ell\u00e1t\u00e1st k\u00edn\u00e1lunk gy\u00f3gyszergy\u00e1rt\u00f3k \u00e9s kutat\u00f3int\u00e9zetek sz\u00e1m\u00e1ra.<\/p>\n<p><strong>El\u0151nyeink:<\/strong><\/p>\n<ul>\n<li>Magas tisztas\u00e1g\u00fa (\u226599,0%)<\/li>\n<li>\u00c1lland\u00f3 min\u0151s\u00e9g a COA-val<\/li>\n<li>T\u00f6meges sz\u00e1ll\u00edt\u00e1si kapacit\u00e1s<\/li>\n<li>Technikai t\u00e1mogat\u00e1s \u00e9s dokument\u00e1ci\u00f3<\/li>\n<li>Vil\u00e1gszerte sz\u00e1ll\u00edtunk<\/li>\n<\/ul>\n<h2>Kapcsol\u00f3d\u00f3 term\u00e9kek<\/h2>\n<p>Fedezze fel egy\u00e9b gy\u00f3gyszeripari k\u00f6ztes term\u00e9keinket \u00e9s hat\u00f3anyagainkat:<\/p>\n<ul>\n<li><a href=\"https:\/\/longchangextracts.com\/hu\/termek\/beta-alanie\/\">B\u00e9ta-alanin<\/a> \u2013 Aminosav-kieg\u00e9sz\u00edt\u0151k<\/li>\n<li><a href=\"https:\/\/longchangextracts.com\/hu\/termek\/nicotinamide\/\">Nikotinamid<\/a> \u2013 B3-vitamin-kieg\u00e9sz\u00edt\u0151<\/li>\n<li><a href=\"https:\/\/longchangextracts.com\/hu\/termek\/ticarcillin-disodium\/\">Ticarcillin-din\u00e1trium<\/a> \u2013 Antibiotikum<\/li>\n<li><a href=\"https:\/\/longchangextracts.com\/hu\/termek\/omeprazole\/\">omeprazol<\/a> \u2013 Protonpumpa-g\u00e1tl\u00f3<\/li>\n<li><a href=\"https:\/\/longchangextracts.com\/hu\/termek\/ornidazole\/\">Ornidazol<\/a> \u2013 Protozoonellenes szer<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Clopidogrel (CAS 113665-84-2) What is Clopidogrel? Clopidogrel is a potent antiplatelet agent belonging to the thienopyridine class of drugs. Known commercially as Plavix, it is widely used to prevent blood clots in patients with cardiovascular conditions. As a prodrug, clopidogrel requires metabolic activation in the liver to exert its platelet-inhibiting effects. The compound is synthesized [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Clopidogrel (CAS 113665-84-2) - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/clopidogrel-cas-113665-84-2\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clopidogrel (CAS 113665-84-2) - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Clopidogrel (CAS 113665-84-2) What is Clopidogrel? Clopidogrel is a potent antiplatelet agent belonging to the thienopyridine class of drugs. Known commercially as Plavix, it is widely used to prevent blood clots in patients with cardiovascular conditions. As a prodrug, clopidogrel requires metabolic activation in the liver to exert its platelet-inhibiting effects. 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Known commercially as Plavix, it is widely used to prevent blood clots in patients with cardiovascular conditions. As a prodrug, clopidogrel requires metabolic activation in the liver to exert its platelet-inhibiting effects. 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