{"id":10589,"date":"2026-03-07T13:20:25","date_gmt":"2026-03-07T13:20:25","guid":{"rendered":"https:\/\/longchangextracts.com\/baicalin-cas-21967-41-9-complete-guide-to-this-potent-flavonoid-from-baikal-skullcap\/"},"modified":"2026-03-07T13:20:25","modified_gmt":"2026-03-07T13:20:25","slug":"baicalin-cas-21967-41-9-complete-guide-to-this-potent-flavonoid-from-baikal-skullcap","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/hu\/baicalin-cas-21967-41-9-complete-guide-to-this-potent-flavonoid-from-baikal-skullcap\/","title":{"rendered":"Baicalin (CAS 21967-41-9): Complete Guide to This Potent Flavonoid from Baikal Skullcap"},"content":{"rendered":"

Baicalin is a powerful flavonoid compound extracted from the roots of Scutellaria baicalensis<\/em>, commonly known as Baikal Skullcap. This comprehensive guide explores the scientific research, health benefits, uses, and safety considerations of baicalin (CAS 21967-41-9).<\/p>\n

What is Baicalin?<\/h2>\n

Baicalin is a flavonoid glycoside with the molecular formula C21<\/sub>H18<\/sub>O11<\/sub> and CAS number 21967-41-9. It is also known by its systematic name baicalein 7-glucuronide, as it is the glucuronide conjugate of baicalein. This compound is one of the main bioactive constituents found in the traditional Chinese medicinal herb Huang Qin (Baikal Skullcap).<\/p>\n

As a flavone glycoside, baicalin exhibits remarkable biological activities that have attracted significant scientific interest in recent years. Research has demonstrated its anti-inflammatory, antioxidant, antiviral, antitumor, antibacterial, anticonvulsant, hepatoprotective, and neuroprotective properties.<\/p>\n

Key Health Benefits of Baicalin<\/h2>\n

1. Potent Anti-Inflammatory Effects<\/h3>\n

Baicalin demonstrates powerful anti-inflammatory properties by modulating inflammatory pathways and reducing pro-inflammatory cytokines. Studies have shown it can significantly decrease levels of interleukin-1 beta (IL-1\u03b2), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-\u03b1). This makes it a promising natural compound for managing inflammatory conditions.<\/p>\n

2. Neuroprotective and Anxiolytic Effects<\/h3>\n

Research indicates that baicalin acts as a positive allosteric modulator of the GABAA<\/sub> receptor, producing anxiolytic (anti-anxiety) effects without sedative or myorelaxant side effects. Studies in animal models have shown that baicalin can dramatically ameliorate chronic stress-induced depressive-like symptoms and exhibit neuroprotective effects against oxidative stress.<\/p>\n

3. Antiviral Activity<\/h3>\n

Baicalin has demonstrated significant antiviral properties, including inhibition of HIV-1 replication by blocking the activity of reverse transcriptase (HIV-1 RT). It has also shown potential benefits in hepatitis B virus (HBV)-infected conditions and other viral infections.<\/p>\n

4. Anticancer Potential<\/h3>\n

Studies suggest baicalin exhibits antitumor activities against various cancers, including liver cancer (particularly HBV-infected liver cancer), hepatic cancer, and cervical cancer. Its mechanisms involve inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways.<\/p>\n

5. Hepatoprotective Properties<\/h3>\n

Baicalin has shown protective effects on the liver, making it valuable in supporting liver health and protecting against liver damage from various sources including toxins and viral infections.<\/p>\n

6. Skin Health and UV Protection<\/h3>\n

In cosmetic applications, baicalin can absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit melanin production. These properties make it beneficial for protecting skin from UV damage, minimizing inflammation, and promoting collagen production.<\/p>\n

7. Antioxidant Activity<\/h3>\n

As a flavonoid, baicalin possesses strong antioxidant properties that help neutralize free radicals and protect cells from oxidative stress, which is linked to aging and various chronic diseases.<\/p>\n

Baicalin vs. Baicalein: What’s the Difference?<\/h2>\n

Baicalin and baicalein are closely related flavonoids from the same plant source. The key difference is that baicalin is the glucuronide conjugate of baicalein, meaning it is baicalein bound to a glucuronic acid molecule. This makes baicalin more water-soluble than baicalein.<\/p>\n

Both compounds share similar biological activities, but baicalin is often preferred for supplement formulations due to its better solubility and bioavailability. In the body, baicalin can be converted to baicalein.<\/p>\n

Typical Dosage and Supplementation<\/h2>\n

Based on clinical research, baicalin supplements are typically taken in doses ranging from 200-800 mg per day, divided into multiple doses (usually morning and evening). A randomized, double-blind clinical trial involving 72 healthy participants who received single oral doses of baicalin ranging from 100 to 2800 mg reported no negative side effects, suggesting a favorable safety profile.<\/p>\n

However, it is important to consult with a healthcare professional before starting any new supplement regimen, especially for individuals with existing health conditions or those taking medications.<\/p>\n

Biztons\u00e1g \u00e9s mell\u00e9khat\u00e1sok<\/h2>\n

Current research indicates that baicalin has a favorable safety profile. Clinical studies have not reported significant adverse effects at therapeutic doses. However, as with any bioactive compound, some individuals may experience:<\/p>\n

    \n
  • Mild gastrointestinal discomfort<\/li>\n
  • Potential interactions with certain medications<\/li>\n
  • Effects on blood sugar levels<\/li>\n<\/ul>\n

    Pregnant or breastfeeding women should consult their healthcare provider before using baicalin supplements. Due to its effects on GABA receptors, individuals taking benzodiazepines or other CNS depressants should use caution.<\/p>\n

    Alkalmaz\u00e1sok \u00e9s felhaszn\u00e1l\u00e1si ter\u00fcletek<\/h2>\n

    Gy\u00f3gyszeripari alkalmaz\u00e1sok<\/h3>\n
      \n
    • Anti-inflammatory medications<\/li>\n
    • Neuroprotective and cognitive support supplements<\/li>\n
    • Antiviral formulations<\/li>\n
    • Hepatoprotective agents<\/li>\n
    • Anticancer adjuvant therapies<\/li>\n<\/ul>\n

      Cosmetic and Skincare Products<\/h3>\n
        \n
      • Anti-aging skincare formulations<\/li>\n
      • UV protection products<\/li>\n
      • Skin lightening and brightening creams<\/li>\n
      • Anti-inflammatory skincare for sensitive skin<\/li>\n<\/ul>\n

        Nutraceuticals<\/h3>\n
          \n
        • General health supplements<\/li>\n
        • Stress and mood support formulations<\/li>\n
        • Antioxidant supplement blends<\/li>\n
        • Sleep support products<\/li>\n<\/ul>\n

          K\u00f6vetkeztet\u00e9s<\/h2>\n

          Baicalin (CAS 21967-41-9) is a scientifically-backed flavonoid with a wide range of potential health benefits. From its anti-inflammatory and neuroprotective properties to its antiviral and anticancer potential, this compound from Baikal Skullcap represents a promising natural ingredient for pharmaceutical, cosmetic, and nutraceutical applications.<\/p>\n

          As research continues to unfold, baicalin is gaining recognition as a valuable natural compound with multiple therapeutic applications. However, consumers should seek products from reputable suppliers that provide third-party testing and clear labeling to ensure quality and purity.<\/p>\n

          Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before using any dietary supplement.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Baicalin is a powerful flavonoid compound extracted from the roots of Scutellaria baicalensis, commonly known as Baikal Skullcap. This comprehensive guide explores the scientific research, health benefits, uses, and safety considerations of baicalin (CAS 21967-41-9). What is Baicalin? Baicalin is a flavonoid glycoside with the molecular formula C21H18O11 and CAS number 21967-41-9. It is also […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"yoast_head":"\nBaicalin (CAS 21967-41-9): Complete Guide to This Potent Flavonoid from Baikal Skullcap - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/hu\/baicalin-cas-21967-41-9-complete-guide-to-this-potent-flavonoid-from-baikal-skullcap\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Baicalin (CAS 21967-41-9): Complete Guide to This Potent Flavonoid from Baikal Skullcap - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Baicalin is a powerful flavonoid compound extracted from the roots of Scutellaria baicalensis, commonly known as Baikal Skullcap. 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