Bis(2-chloroethyl)amine Hydrochloride (CAS 821-48-7): A Key Intermediate in Organic Synthesis
What is Bis(2-chloroethyl)amine Hydrochloride?
Bis(2-chloroethyl)amine hydrochloride, also known as 2,2′-Dichlorodiethylamine hydrochloride or beta,beta’-Dichlorodiethylamine, is a chemical compound with the molecular formula C4H10Cl3N and a molecular weight of 178.49 g/mol. This versatile chemical appears as a white to light yellow or light orange crystalline powder and is available in high purity grades (typically >99.0%).
This compound serves as a fundamental building block in organic synthesis and is classified as a nitrogen mustard analog. It is widely recognized in the chemical research community for its role as an essential intermediate in the synthesis of various piperazine derivatives and other nitrogen-containing heterocyclic compounds.
What Are the Applications and Uses?
Chemical Synthesis Intermediate
Bis(2-chloroethyl)amine hydrochloride is primarily used as an intermediate in chemical synthesis. Its molecular structure contains two chloroethyl groups attached to a nitrogen atom, making it highly reactive and suitable for various substitution reactions. The primary applications include:
- Piperazine Derivative Synthesis: This compound serves as a crucial starting material for synthesizing piperazine derivatives, which are important heterocyclic compounds used in pharmaceutical research and drug development.
- Heterocyclic Compound Formation: The compound is employed in the construction of nitrogen-containing heterocyclic rings, which form the backbone of many pharmaceutical agents.
- Pharmaceutical Research: As a cytotoxic metabolite of cyclophosphamide (a widely used chemotherapy drug), it plays a role in cancer research anti-cancer agents. and the development of
Research Applications
In laboratory settings, Bis(2-chloroethyl)amine hydrochloride is utilized as:
- A biochemical reagent for proteomics research
- A biological material for life science research
- A building block in medicinal chemistry programs
- An intermediate in the synthesis of nitrogen mustard compounds
Biztonság és kezelés
Kémiai tulajdonságok
- Megjelenés: White to light yellow/orange crystalline powder
- Tisztaság: Typically >99.0%
- Oldhatóság: Partly miscible in water
- Tárolás: Should be stored in a cool, dry place away from incompatible materials
Biztonsági óvintézkedések
Bis(2-chloroethyl)amine hydrochloride is a chemical intermediate intended for professional use in research laboratories and industrial settings. When handling this compound:
- Always wear appropriate personal protective equipment (PPE) including gloves, goggles, and lab coat
- Work in a well-ventilated area or fume hood
- Avoid inhalation, ingestion, or skin contact
- Follow all relevant Safety Data Sheet (SDS) guidelines
- Dispose of this material in accordance with local environmental regulations
Note: This compound is a cytotoxic agent related to nitrogen mustard compounds and should be handled with appropriate care by trained professionals.
Chemical Specifications
| Property | Érték |
| CAS-szám | 821-48-7 |
| Molekuláris képlet | C4H10Cl3N |
| Molekulatömeg | 178.49 g/mol |
| Tisztaság | >99.0% |
| Megjelenés | White to light yellow/orange crystalline |
| Oldhatóság | Partly miscible in water |
Frequently Asked Questions
What is Bis(2-chloroethyl)amine hydrochloride used for?
It is primarily used as a chemical intermediate for synthesizing piperazine derivatives and other nitrogen-containing heterocyclic compounds in pharmaceutical research and chemical synthesis.
Is Bis(2-chloroethyl)amine hydrochloride dangerous?
As a cytotoxic compound and nitrogen mustard analog, it requires careful handling. Professional users should follow all safety protocols and use appropriate protective equipment.
What is the purity level available?
High-purity grades (typically >99.0%) are available from commercial suppliers for research and industrial applications.
How should this chemical be stored?
Store in a cool, dry location in tightly sealed containers away from incompatible substances. Follow manufacturer and safety data sheet recommendations.
Why Choose Our Bis(2-chloroethyl)amine Hydrochloride?
- High Purity: Our product meets or exceeds >99.0% purity standards
- Quality Assurance: Each batch is tested to ensure consistent quality
- Reliable Supply: Stable inventory for ongoing research needs
- Technical Support: Our team provides technical assistance and documentation including SDS
- Competitive Pricing: Cost-effective solutions for research and industrial applications
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