{"id":5277,"date":"2024-08-04T18:08:09","date_gmt":"2024-08-04T18:08:09","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5277"},"modified":"2024-08-04T18:08:09","modified_gmt":"2024-08-04T18:08:09","slug":"grass-fruit-on-%ce%b1-glucosidase","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/fr\/grass-fruit-on-%ce%b1-glucosidase\/","title":{"rendered":"\u00c9tude de la composition chimique et de l'activit\u00e9 d'inhibition de l'\u03b1-glucosidase par les fruits de l'herbe"},"content":{"rendered":"

\u00c9tude de la composition chimique et de l'activit\u00e9 d'inhibition de l'\u03b1-glucosidase par les fruits de l'herbe
\nAmomum tsao ko Crevost&Lemarie sont des plantes herbac\u00e9es vivaces de la famille du gingembre et du genre cardamome, principalement distribu\u00e9es dans des provinces telles que le Yunnan, le Guangxi et le Guizhou en Chine. Les fruits utilis\u00e9s en m\u00e9decine ont pour fonction d'ass\u00e9cher l'humidit\u00e9, de revigorer la rate, d'\u00e9liminer les mucosit\u00e9s et d'intercepter le paludisme. Ils peuvent \u00e9galement \u00eatre utilis\u00e9s comme \u00e9pices pour extraire des huiles aromatiques et constituent un type de vari\u00e9t\u00e9 m\u00e9dicinale et comestible \u00e0 double usage. En tant que vari\u00e9t\u00e9 m\u00e9dicinale et comestible courante en Chine, la composition chimique et les effets pharmacologiques du fruit de l'herbe ont \u00e9t\u00e9 largement \u00e9tudi\u00e9s. En termes de composition chimique, outre les composants de l'huile volatile, on trouve principalement des flavono\u00efdes, des ph\u00e9nols et des diph\u00e9nylheptanes. Parmi eux, les flavono\u00efdes sont principalement signal\u00e9s pour leurs activit\u00e9s anti-inflammatoires et antioxydantes, les ph\u00e9nols sont principalement signal\u00e9s pour leurs activit\u00e9s antioxydantes, et les diph\u00e9nylheptanes sont largement signal\u00e9s pour leurs activit\u00e9s anti-tumorales et inhibitrices de l'\u03b1-glucosidase.<\/p>\n

Le diab\u00e8te est une maladie m\u00e9tabolique caract\u00e9ris\u00e9e par une hyperglyc\u00e9mie et de multiples complications. Ces derni\u00e8res ann\u00e9es, il est devenu le troisi\u00e8me \"tueur en sant\u00e9\" apr\u00e8s les maladies cardiovasculaires et c\u00e9r\u00e9brovasculaires et le cancer. L'inhibiteur de l'\u03b1-glucosidase peut contr\u00f4ler le d\u00e9veloppement du diab\u00e8te, en particulier l'apparition de complications, en r\u00e9duisant le pic de glucose sanguin postprandial. Il s'agit d'un m\u00e9dicament prometteur pour le traitement du diab\u00e8te. L'acarbose, le voglibose et le miglitol sont actuellement les inhibiteurs de l'\u03b1-glucosidase les plus utilis\u00e9s dans la pratique clinique, mais ils sont co\u00fbteux, ont des effets secondaires tels que des troubles de l'appareil digestif, une hypoglyc\u00e9mie entra\u00eenant un choc, et ne peuvent pas traiter efficacement les complications du diab\u00e8te. Il est tr\u00e8s important d'explorer de nouveaux inhibiteurs de l'\u03b1-glucosidase. La recherche a montr\u00e9 que la poudre s\u00e8che et l'extrait du fruit de l'herbe ont des fonctions hypoglyc\u00e9miques et inhibent les activit\u00e9s li\u00e9es \u00e0 l'\u03b1-glucosidase, mais il n'y a pas d'\u00e9tude pertinente sur les effets hypoglyc\u00e9miques de ses composants monom\u00e8res. Cette \u00e9tude a permis d'extraire et de s\u00e9parer syst\u00e9matiquement les fruits de l'herbe et de constater que les composants monom\u00e8res enrichissaient la diversit\u00e9 chimique de l'esp\u00e8ce. Des compos\u00e9s inhibiteurs de l'alpha glucosidase ont \u00e9galement \u00e9t\u00e9 d\u00e9couverts, ce qui devrait apporter de nouvelles id\u00e9es pour l'utilisation clinique de la m\u00e9decine traditionnelle chinoise.<\/p>\n

\"\"\"\"\"\"\"\"
\nDans cette \u00e9tude, 11 compos\u00e9s ont \u00e9t\u00e9 isol\u00e9s du fruit de l'herbe de la m\u00e9decine traditionnelle chinoise. Le compos\u00e9 1 est un compos\u00e9 ph\u00e9nolique, qui a \u00e9t\u00e9 signal\u00e9 pour la premi\u00e8re fois comme produit naturel. Les compos\u00e9s 2, 8 et 9 sont des compos\u00e9s ph\u00e9noliques et d'acides gras isol\u00e9s du genre cardamome pour la premi\u00e8re fois. Des tests d'inhibition de l'\u03b1-glucosidase ont r\u00e9v\u00e9l\u00e9 que deux compos\u00e9s de diph\u00e9nylheptane ont une activit\u00e9 plus forte que celle de l'acarbose, un m\u00e9dicament commercialis\u00e9. Des \u00e9tudes ant\u00e9rieures ont montr\u00e9 que l'extrait d'alcool du fruit de l'herbe a une activit\u00e9 inhibitrice contre l'\u03b1-glucosidase, alors que les autres composants monom\u00e8res de cette \u00e9tude n'ont pas montr\u00e9 d'activit\u00e9 inhibitrice significative. On suppose que ces compos\u00e9s diph\u00e9nylheptane sont l'une des bases mat\u00e9rielles de l'effet hypoglyc\u00e9mique du fruit de l'herbe in vitro. L'inhibiteur de l'\u03b1-glucosidase a \u00e9t\u00e9 largement utilis\u00e9 ces derni\u00e8res ann\u00e9es comme m\u00e9dicament pour le traitement clinique du diab\u00e8te de type 2. Cette \u00e9tude enrichit non seulement la diversit\u00e9 des composants du Caoguo, un rem\u00e8de traditionnel chinois, mais devrait \u00e9galement permettre de d\u00e9couvrir une nouvelle voie d'application clinique du Caoguo, un rem\u00e8de traditionnel chinois, en inhibant l'activit\u00e9 de l'\u03b1-glucosidase \u00e0 l'aide de ses composants monom\u00e8res.<\/p>","protected":false},"excerpt":{"rendered":"

Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 – Glucosidase Amomum tsao ko Crevost&Lemarie are perennial herbaceous plants of the ginger family and cardamom genus, mainly distributed in provinces such as Yunnan, Guangxi, and Guizhou in China. Fruits used as medicine have the functions of drying dampness, invigorating the spleen, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nStudy on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 - Glucosidase - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/fr\/grass-fruit-on-\u03b1-glucosidase\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 - Glucosidase - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 – Glucosidase Amomum tsao ko Crevost&Lemarie are perennial herbaceous plants of the ginger family and cardamom genus, mainly distributed in provinces such as Yunnan, Guangxi, and Guizhou in China. 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