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Calcifediol Monohydrate<\/strong>, also known as 25-Hydroxyvitamin D3 Monohydrate<\/strong> ou 25-Hydroxycholecalciferol Monohydrate<\/strong>, is the major circulating metabolite of vitamin D3 in the human body. This compound serves as a crucial prehormone and is produced in the liver through the hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase.<\/p>\n Calcifediol represents a vital intermediate in the vitamin D metabolic pathway. Unlike its precursor vitamin D3 or its active form calcitriol (1,25-dihydroxyvitamin D3), calcifediol has a longer half-life in the bloodstream and is considered the best indicator of a patient’s vitamin D status. This makes it clinically significant for diagnosing and monitoring vitamin D deficiency.<\/p>\n Calcifediol is considered the best biomarker for assessing vitamin D status<\/strong> in patients. Unlike other vitamin D metabolites, it has a circulating half-life of approximately 2-3 weeks, making it more stable for laboratory measurements. Healthcare providers worldwide measure calcifediol concentrations to determine whether a patient has sufficient vitamin D levels.<\/p>\n Calcifediol monohydrate is used as a supplement for treating vitamin D deficiency<\/strong>. It offers advantages over other forms of vitamin D because:<\/p>\n One of the most important therapeutic applications of calcifediol is in treating secondary hyperparathyroidism associated with chronic kidney disease<\/strong>. Patients with CKD often have impaired kidney function that affects vitamin D activation. Extended-release calcifediol formulations have been shown to:<\/p>\n Research has shown that calcifediol monohydrate may provide benefits for skin health:<\/p>\n Calcifediol plays a role in immune system modulation and may:<\/p>\n Calcifediol is used in various dietary supplement formulations for:<\/p>\n Calcifediol monohydrate is safe under recommended conditions<\/strong> and levels of use. Research indicates:<\/p>\n When taken in excessive amounts, calcifediol may cause:<\/p>\n When sourcing Calcifediol Monohydrate (CAS 63283-36-3) for your pharmaceutical, research, or supplement applications, our company offers:<\/p>\n We supply Calcifediol Monohydrate to pharmaceutical companies, research institutions, and supplement manufacturers globally. Contact us for quotes on bulk orders, custom specifications, and packaging options tailored to your needs.<\/p>\n A:<\/strong> Calcifediol (25-hydroxyvitamin D3) is the major circulating form of vitamin D and requires further activation in the kidneys to become calcitriol (1,25-dihydroxyvitamin D3), the biologically active form.<\/p>\n A:<\/strong> Serum calcifediol concentration is measured to assess vitamin D status because it has a longer half-life and reflects the body’s vitamin D stores more accurately than other forms.<\/p>\n A:<\/strong> Yes, extended-release calcifediol is specifically approved for treating secondary hyperparathyroidism in patients with stage 3-4 chronic kidney disease.<\/p>\n A:<\/strong> The CAS number for Calcifediol Monohydrate is 63283-36-3.<\/p>\n A:<\/strong> Research indicates calcifediol is safe for pregnant and lactating women when used at recommended levels. However, consult a healthcare provider before use.<\/p>\n Calcifediol Monohydrate (CAS 63283-36-3) is a crucial metabolite in the vitamin D pathway with significant clinical and therapeutic applications. Its role as the best indicator of vitamin D status, combined with its effectiveness in treating vitamin D deficiency and chronic kidney disease-related conditions, makes it an important compound in both clinical and research settings.<\/p>\n For pharmaceutical companies, research institutions, and supplement manufacturers seeking high-quality Calcifediol Monohydrate, our product offers reliability, purity, and comprehensive technical support.<\/p>\n This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before using any supplement or medication.<\/em><\/p>","protected":false},"excerpt":{"rendered":"What is Calcifediol Monohydrate? Calcifediol Monohydrate, also known as 25-Hydroxyvitamin D3 Monohydrate or 25-Hydroxycholecalciferol Monohydrate, is the major circulating metabolite of vitamin D3 in the human body. This compound serves as a crucial prehormone and is produced in the liver through the hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase. Calcifediol represents a [...]","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[],"yoast_head":"\nChemical Properties of Calcifediol Monohydrate<\/h2>\n
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\n Num\u00e9ro CAS<\/strong><\/td>\n 63283-36-3<\/td>\n<\/tr>\n \n Formule mol\u00e9culaire<\/strong><\/td>\n C\u2082\u2087H\u2084\u2084O\u2082 \u00b7 H\u2082O<\/td>\n<\/tr>\n \n Poids mol\u00e9culaire<\/strong><\/td>\n 418.65 g\/mol<\/td>\n<\/tr>\n \n Synonymes<\/strong><\/td>\n 25-Hydroxyvitamin D3, 25-Hydroxycholecalciferol, Calcidiol<\/td>\n<\/tr>\n \n Apparence<\/strong><\/td>\n Poudre ou cristaux de couleur blanche \u00e0 jaune clair<\/td>\n<\/tr>\n \n La puret\u00e9<\/strong><\/td>\n \u226598% (HPLC)<\/td>\n<\/tr>\n \n Solubilit\u00e9<\/strong><\/td>\n Soluble in organic solvents<\/td>\n<\/tr>\n \n Classification<\/strong><\/td>\n API (principe actif pharmaceutique)<\/td>\n<\/tr>\n<\/table>\n Benefits and Therapeutic Applications<\/h2>\n
Vitamin D Status Indicator<\/h3>\n
Treatment of Vitamin D Deficiency<\/h3>\n
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Chronic Kidney Disease (CKD) Management<\/h3>\n
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Skin Health Benefits<\/h3>\n
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Immunomodulatory Effects<\/h3>\n
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Utilisations et applications<\/h2>\n
Applications pharmaceutiques<\/h3>\n
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Applications de la recherche<\/h3>\n
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Nutritional Supplements<\/h3>\n
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S\u00e9curit\u00e9 et effets ind\u00e9sirables<\/h2>\n
S\u00e9curit\u00e9 g\u00e9n\u00e9rale<\/h3>\n
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Effets secondaires possibles<\/h3>\n
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Contre-indications et pr\u00e9cautions<\/h3>\n
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Why Choose Our Calcifediol Monohydrate?<\/h2>\n
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Foire aux questions<\/h2>\n
Q: What is the difference between calcifediol and calcitriol?<\/h3>\n
Q: How is calcifediol used in diagnosing vitamin D deficiency?<\/h3>\n
Q: Is calcifediol safe for kidney disease patients?<\/h3>\n
Q: What is the CAS number for calcifediol?<\/h3>\n
Q: Can calcifediol be used during pregnancy?<\/h3>\n
Conclusion<\/h2>\n
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