{"id":10641,"date":"2026-03-10T00:16:42","date_gmt":"2026-03-10T00:16:42","guid":{"rendered":"https:\/\/longchangextracts.com\/adefovir-cas-106941-25-7-complete-guide-to-this-antiviral-compound\/"},"modified":"2026-03-10T00:16:42","modified_gmt":"2026-03-10T00:16:42","slug":"adefovir-cas-106941-25-7-complete-guide-to-this-antiviral-compound","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/fr\/adefovir-cas-106941-25-7-complete-guide-to-this-antiviral-compound\/","title":{"rendered":"Adefovir (CAS 106941-25-7): Complete Guide to This Antiviral Compound"},"content":{"rendered":"<h2>What is Adefovir?<\/h2>\n<p>Adefovir, with the CAS number 106941-25-7, is a potent antiviral medication classified as an acyclic phosphonate nucleotide analog of dAMP. It is commercially known by its trade names Preveon and Hepsera. This compound is primarily used for the treatment of chronic hepatitis B virus (HBV) infections.<\/p>\n<h2>Propri\u00e9t\u00e9s chimiques<\/h2>\n<ul>\n<li><strong>Formule mol\u00e9culaire<\/strong>: C\u2088H\u2081\u2082N\u2085O\u2084P<\/li>\n<li><strong>Poids mol\u00e9culaire<\/strong>: 273.19 g\/mol<\/li>\n<li><strong>Num\u00e9ro CAS<\/strong>: 106941-25-7<\/li>\n<li><strong>Synonymes<\/strong>: GS-0393, GS-393, PMEA, 9-(2-phosphonylmethoxyethyl)adenine<\/li>\n<li><strong>Apparence<\/strong>: White to off-white powder<\/li>\n<li><strong>La puret\u00e9<\/strong>: \u226598% (HPLC)<\/li>\n<\/ul>\n<h2>M\u00e9canisme d'action<\/h2>\n<p>Adefovir works as a DNA polymerase inhibitor. It exerts its antiviral activity by:<\/p>\n<ol>\n<li><strong>Inhibiting reverse transcriptase<\/strong> &#8211; Blocks HIV-1 replication<\/li>\n<li><strong>Inhibiting polymerase activity<\/strong> &#8211; Prevents HBV DNA replication<\/li>\n<li><strong>Chain termination<\/strong> &#8211; Incorporates into viral DNA, causing premature termination<\/li>\n<\/ol>\n<p>The compound is converted to its active diphosphate form inside cells, which then competitively inhibits viral DNA polymerase.<\/p>\n<h2>Applications and Uses<\/h2>\n<h3>Pharmaceutical Applications<\/h3>\n<ul>\n<li><strong>Hepatitis B Treatment<\/strong>: Primary indication for chronic HBV infection<\/li>\n<li><strong>HIV Therapy<\/strong>: Shows activity against HIV-1<\/li>\n<li><strong>Antiviral Research<\/strong>: Widely used in antiviral drug development<\/li>\n<\/ul>\n<h3>Research Applications<\/h3>\n<ul>\n<li>Laboratory research on nucleotide analogs<\/li>\n<li>Development of new antiviral therapies<\/li>\n<li>Studies on viral resistance mechanisms<\/li>\n<\/ul>\n<h2>Benefits<\/h2>\n<ol>\n<li><strong>Broad-spectrum antiviral activity<\/strong> &#8211; Effective against multiple viruses including HBV and herpesviruses<\/li>\n<li><strong>Oral bioavailability<\/strong> &#8211; Can be administered in prodrug form (adefovir dipivoxil)<\/li>\n<li><strong>Well-established safety profile<\/strong> &#8211; Approved for clinical use<\/li>\n<li><strong>Resistance management<\/strong> &#8211; Used in treatment-experienced patients<\/li>\n<\/ol>\n<h2>Informations sur la s\u00e9curit\u00e9<\/h2>\n<h3>Handling Precautions<\/h3>\n<ul>\n<li>Handle with care in a controlled environment<\/li>\n<li>Use appropriate personal protective equipment (PPE)<\/li>\n<li>Store at recommended conditions<\/li>\n<\/ul>\n<h3>Stockage<\/h3>\n<ul>\n<li>Store in a cool, dry place<\/li>\n<li>Keep away from direct sunlight<\/li>\n<li>Maintain proper ventilation<\/li>\n<\/ul>\n<h3>Statut r\u00e9glementaire<\/h3>\n<p>Adefovir is a prescription medication and must be used under medical supervision. It is approved by regulatory agencies including FDA and EMA for the treatment of chronic hepatitis B.<\/p>\n<h2>Why Choose Our Adefovir?<\/h2>\n<ul>\n<li><strong>High purity<\/strong> (\u226598% HPLC)<\/li>\n<li><strong>Consistent quality<\/strong> with batch-to-batch reliability<\/li>\n<li><strong>Competitive pricing<\/strong> for research and pharmaceutical applications<\/li>\n<li><strong>Technical support<\/strong> available for handling and applications<\/li>\n<li><strong>Reliable supply chain<\/strong> for bulk orders<\/li>\n<\/ul>\n<h2>Frequently Asked Questions<\/h2>\n<details>\n<summary><strong>Q: What is Adefovir used for?<\/strong><\/summary>\n<p>A: Adefovir is primarily used to treat chronic hepatitis B virus (HBV) infections. It may also have applications in HIV research.<\/p>\n<\/details>\n<details>\n<summary><strong>Q: How does Adefovir work?<\/strong><\/summary>\n<p>A: Adefovir inhibits viral DNA polymerase and reverse transcriptase enzymes, preventing viral replication.<\/p>\n<\/details>\n<details>\n<summary><strong>Q: Is Adefovir the same as Tenofovir?<\/strong><\/summary>\n<p>A: No, they are different but related compounds. Both are nucleotide analogs used as antivirals, but Tenofovir is more commonly used today due to better safety profile.<\/p>\n<\/details>\n<details>\n<summary><strong>Q: What is the CAS number for Adefovir?<\/strong><\/summary>\n<p>A: The CAS number for Adefovir is 106941-25-7.<\/p>\n<\/details>\n<p><em>This article is for informational purposes only. For medical use, please consult healthcare professionals.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Adefovir (CAS 106941-25-7) is a potent antiviral compound used for treating chronic hepatitis B virus infections. 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