{"id":7504,"date":"2024-08-06T20:14:42","date_gmt":"2024-08-06T20:14:42","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7504"},"modified":"2024-08-06T20:14:42","modified_gmt":"2024-08-06T20:14:42","slug":"selenium-rich-ganoderma-lucidum-mycelium","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/es\/selenium-rich-ganoderma-lucidum-mycelium\/","title":{"rendered":"Extracci\u00f3n de polisac\u00e1ridos y prote\u00ednas del micelio de Ganoderma lucidum rico en selenio y sus actividades antioxidante y antitumoral in vitro"},"content":{"rendered":"<p>Extracci\u00f3n de polisac\u00e1ridos y prote\u00ednas del micelio de Ganoderma lucidum rico en selenio y sus actividades antioxidante y antitumoral in vitro<br \/>\nEn los \u00faltimos a\u00f1os, 90% de los pacientes con tumores malignos han muerto por met\u00e1stasis de c\u00e9lulas cancerosas. Existe una relaci\u00f3n causal entre la aparici\u00f3n y el desarrollo de tumores y la baja funci\u00f3n inmunitaria del organismo. Seg\u00fan los informes, el selenio puede mejorar el sistema inmunol\u00f3gico del cuerpo y resistir la aparici\u00f3n de enfermedades tumorales, pero el cuerpo humano s\u00f3lo puede depender de la ingesta externa de selenio org\u00e1nico, que se compone principalmente de polisac\u00e1ridos de selenio y prote\u00ednas de selenio. Seg\u00fan informes anteriores, los polisac\u00e1ridos de selenio del hongo negro y del t\u00e9 tienen una fuerte actividad antioxidante. Los polisac\u00e1ridos de selenio tambi\u00e9n pueden inhibir la actividad de las c\u00e9lulas tumorales: Shang et al descubrieron que el polisac\u00e1rido de selenio de la calabaza tiene cierto efecto inhibidor sobre el crecimiento de las c\u00e9lulas del c\u00e1ncer de mama. Adem\u00e1s de tener cierta capacidad para eliminar los radicales libres, las selenoprote\u00ednas tambi\u00e9n desempe\u00f1an un papel importante en la inhibici\u00f3n del crecimiento tumoral: la selenoprote\u00edna de Brassica napus tiene una gran capacidad para eliminar los radicales libres y un poder reductor total; los p\u00e9ptidos de prote\u00edna de soja ricos en selenio pueden inhibir significativamente el crecimiento tumoral en ratones.<\/p>\n<p>El Ganoderma lucidum pertenece al filo Basidiomycota, a la familia Actinobacteriaceae y al g\u00e9nero Ganoderma (Leyss. ex Fr.) Karst Los hongos medicinales son hongos tradicionales de China de doble uso alimentario y medicinal, que incluyen diversos principios activos como triterpenos, polisac\u00e1ridos, prote\u00ednas, etc. Tienen una amplia gama de actividades farmacol\u00f3gicas, como antitumorales, antioxidantes y de regulaci\u00f3n inmunol\u00f3gica. El lingzhi tiene una gran capacidad para enriquecer el selenio. El Ganoderma lucidum rico en selenio se obtiene cultivando Ganoderma lucidum como portador para la conversi\u00f3n del selenio, lo que combina la actividad biol\u00f3gica del Ganoderma lucidum y el selenio. En la actualidad, la investigaci\u00f3n de los estudiosos se centra principalmente en el cultivo y la cepa de cultivo de Ganoderma lucidum rico en selenio, y la investigaci\u00f3n de la actividad biol\u00f3gica relacionada se lleva a cabo principalmente a trav\u00e9s de experimentos con animales, con relativamente pocos experimentos antitumorales in vitro. En este estudio se utilizaron m\u00e9todos de extracci\u00f3n alcalina asistida por ultrasonidos, extracci\u00f3n con agua y precipitaci\u00f3n con alcohol para extraer polisac\u00e1ridos del micelio de Ganoderma lucidum rico en selenio, y se extrajeron prote\u00ednas solubles del micelio utilizando soluci\u00f3n tamp\u00f3n de fosfato como disolvente. Se investig\u00f3 la capacidad de eliminaci\u00f3n de los polisac\u00e1ridos y las prote\u00ednas del micelio de Ganoderma lucidum rico en selenio frente a los radicales libres DPPH y ABTS, la capacidad de reducci\u00f3n del hierro y el efecto inhibidor sobre la proliferaci\u00f3n de las c\u00e9lulas de c\u00e1ncer de h\u00edgado HCCLM, las c\u00e9lulas de c\u00e1ncer de pulm\u00f3n A549 y las c\u00e9lulas de c\u00e1ncer de boca HSC-3. El grupo de selenio se utiliz\u00f3 para el estudio de los radicales libres DPPH y ABTS. El grupo selenio se utiliz\u00f3 como control para explorar los efectos del selenio sobre los principios activos y las actividades antioxidante y antitumoral del Ganoderma lucidum. Proporcionar una base te\u00f3rica para el posterior desarrollo y aplicaci\u00f3n de los recursos de selenio.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7505\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-308.png\" alt=\"\" width=\"368\" height=\"281\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7506\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-261.png\" alt=\"\" width=\"366\" height=\"256\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7507\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-25.jpg\" alt=\"\" width=\"659\" height=\"246\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7508\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-20.jpg\" alt=\"\" width=\"664\" height=\"200\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7509\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-19.jpg\" alt=\"\" width=\"654\" height=\"199\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-19.jpg 654w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-19-650x199.jpg 650w\" sizes=\"(max-width: 654px) 100vw, 654px\" \/><\/p>\n<p>Utilizando semillas madre de Ganoderma lucidum como materia prima, se a\u00f1adi\u00f3 selenio ex\u00f3geno adecuado para la fermentaci\u00f3n l\u00edquida con el fin de obtener micelio de Ganoderma lucidum rico en selenio, y se investigaron sus actividades polisac\u00e1rida y proteica. Durante el experimento, se utiliz\u00f3 Ganoderma lucidum sin selenio como control correspondiente. Los resultados mostraron que el contenido de polisac\u00e1ridos extra\u00eddos mediante extracci\u00f3n alcalina asistida por ultrasonidos era superior al extra\u00eddo mediante extracci\u00f3n con agua; El contenido de polisac\u00e1ridos de selenio es superior al de polisac\u00e1ridos, y el contenido de prote\u00ednas de selenio es superior al de prote\u00ednas; El contenido de selenio en selenoprote\u00ednas es superior al de polisac\u00e1ridos de selenio. La adici\u00f3n de selenio es beneficiosa para la generaci\u00f3n de selenoprote\u00ednas, y tanto las selenoprote\u00ednas como los polisac\u00e1ridos de selenio tienen ciertos efectos antioxidantes. En experimentos antitumorales in vitro, tanto los polisac\u00e1ridos de selenio como las selenoprote\u00ednas tienen ciertos efectos antitumorales, y los polisac\u00e1ridos de selenio tienen un efecto antitumoral significativo en comparaci\u00f3n con los polisac\u00e1ridos, mientras que las selenoprote\u00ednas tienen efectos antitumorales m\u00e1s pobres.<\/p>\n<p>Este estudio explora las actividades antioxidantes y antitumorales de los polisac\u00e1ridos de selenio y las selenoprote\u00ednas de Ganoderma lucidum, que tienen cierto valor de referencia en la investigaci\u00f3n de la actividad de los extractos de Ganoderma lucidum y ayudan a promover el desarrollo y la utilizaci\u00f3n de recursos ricos en selenio de Ganoderma lucidum y selenio.<\/p>","protected":false},"excerpt":{"rendered":"<p>Extraction of polysaccharides and proteins from selenium rich Ganoderma lucidum mycelium and their in vitro antioxidant and anti-tumor activities In recent years, 90% of patients with malignant tumors have died from cancer cell metastasis. There is a causal relationship between the occurrence and development of tumors and the low immune function of the body. According [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Extraction of polysaccharides and proteins from selenium rich Ganoderma lucidum mycelium and their in vitro antioxidant and anti-tumor activities - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/es\/selenium-rich-ganoderma-lucidum-mycelium\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extraction of polysaccharides and proteins from selenium rich Ganoderma lucidum mycelium and their in vitro antioxidant and anti-tumor activities - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Extraction of polysaccharides and proteins from selenium rich Ganoderma lucidum mycelium and their in vitro antioxidant and anti-tumor activities In recent years, 90% of patients with malignant tumors have died from cancer cell metastasis. There is a causal relationship between the occurrence and development of tumors and the low immune function of the body. 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