{"id":5435,"date":"2024-08-04T18:58:34","date_gmt":"2024-08-04T18:58:34","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5435"},"modified":"2024-08-04T18:58:34","modified_gmt":"2024-08-04T18:58:34","slug":"research-on-non-coumarin-components-in-bai-zhi","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/es\/research-on-non-coumarin-components-in-bai-zhi\/","title":{"rendered":"Investigaci\u00f3n sobre los componentes no cumar\u00ednicos del Bai Zhi"},"content":{"rendered":"Investigaci\u00f3n sobre los componentes no cumar\u00ednicos del Bai Zhi
\nBai Zhi es una planta de la familia de las umbel\u00edferas, Angelica dahurica (Fisch. ex Hoffm.) Benth Et Hook. f. o Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan's dried roots. Sabor picante, naturaleza c\u00e1lida. Tiene los efectos de aliviar los s\u00edntomas, disipar el fr\u00edo, disipar el viento y aliviar el dolor, promover la apertura nasal, secar la humedad y detener los cinturones, y reducir la hinchaz\u00f3n y el pus. En la pr\u00e1ctica cl\u00ednica, se utiliza para tratar resfriados, dolores de cabeza, dolor de cejas, congesti\u00f3n nasal, goteo nasal, congesti\u00f3n nasal, sinusitis nasal, dolor de muelas, flujo vaginal, llagas y \u00falceras dolorosas, etc. Angelica dahurica es uno de los materiales medicinales a granel m\u00e1s utilizados en la pr\u00e1ctica cl\u00ednica. Seg\u00fan las estad\u00edsticas, hasta ahora, 565 variedades de medicinas tradicionales chinas patentadas y preparaciones simples que contienen Angelica dahurica han sido incluidas en la base de datos de prescripciones de medicinas tradicionales chinas patentadas y preparaciones simples, y 1836 prescripciones que contienen Angelica dahurica han sido incluidas en la base de datos de prescripciones de medicina tradicional china. Para dilucidar su base farmacol\u00f3gica, los expertos han aislado e identificado una serie de componentes cumar\u00ednicos de Bai Zhi. Adem\u00e1s, hay informes en la literatura de que Bai Zhi contiene abundantes flavonoides, pero actualmente no hay informes relevantes sobre el aislamiento y purificaci\u00f3n de mon\u00f3meros flavonoides de Bai Zhi. En el estudio sistem\u00e1tico preliminar de la composici\u00f3n qu\u00edmica de Angelica dahurica, el equipo de investigaci\u00f3n descubri\u00f3 que, adem\u00e1s de una gran cantidad de componentes cumar\u00ednicos, Angelica dahurica tambi\u00e9n puede contener componentes no cumar\u00ednicos como alcaloides y flavonoides. Utilizando la tecnolog\u00eda de separaci\u00f3n guiada LC-MS, se descubrieron con \u00e9xito m\u00faltiples d\u00edmeros de cumarina estructuralmente novedosos de Angelica dahurica, y se estudiaron las partes de alta polaridad del extracto etan\u00f3lico de Hangbai dahurica. Se aislaron e identificaron diecis\u00e9is alcaloides pirr\u00f3licos. Este art\u00edculo informa adem\u00e1s del aislamiento e identificaci\u00f3n de compuestos no cumar\u00ednicos de las partes solubles en agua de Angelica dahurica.<\/p>\n
![\"\"](\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-146.png\")
En la literatura sobre la composici\u00f3n qu\u00edmica de Angelica dahurica, se cree generalmente que los principales componentes qu\u00edmicos de Angelica dahurica son compuestos cumar\u00ednicos, mientras que hay pocos informes sobre compuestos no cumar\u00ednicos en Angelica dahurica. Lu et al. aislaron e identificaron un alcaloide pirr\u00f3lico, la cumarina, de Angelica dahurica. En nuestro estudio sistem\u00e1tico de Angelica dahurica, nuestro grupo de investigaci\u00f3n no s\u00f3lo aisl\u00f3 una gran cantidad de cumarinas y d\u00edmeros de cumarina, sino que tambi\u00e9n aisl\u00f3 16 alcaloides pirr\u00f3licos de Angelica dahurica, enriqueciendo nuestra comprensi\u00f3n de su composici\u00f3n qu\u00edmica. En investigaciones posteriores sobre la composici\u00f3n qu\u00edmica de Bai Zhi, se aislaron inesperadamente 18 componentes no cumar\u00ednicos descritos en este art\u00edculo. Adem\u00e1s del alcaloide Jin Qian Cao descrito anteriormente, los otros 17 componentes no cumar\u00ednicos, incluidos 9 flavonoides, 5 lignanos, 2 \u00e9steres fen\u00f3licos simples y 1-H-imidazo [4,5-d] piridazin-2-amina, se aislaron de Bai Zhi por primera vez. Los compuestos 3 y 18 tienen ciertos efectos inhibitorios sobre la liberaci\u00f3n de super\u00f3xido inducida por el zimos\u00e1n a partir de los neutr\u00f3filos, mientras que los compuestos 1 y 18 tienen efectos inhibitorios sobre la liberaci\u00f3n de la actividad NO a partir de las c\u00e9lulas RAW 264.7. Cabe se\u00f1alar que, aunque se han publicado m\u00faltiples informes sobre la presencia de flavonoides en Angelica dahurica, todos ellos son informes preliminares sobre la determinaci\u00f3n del contenido total de flavonoides. Actualmente, no existen informes sobre el aislamiento de flavonoides monom\u00e9ricos de Angelica dahurica. Sin embargo, en este estudio, se obtuvieron por primera vez m\u00faltiples flavonoides y mon\u00f3meros de gluc\u00f3sidos flavonoides de Angelica dahurica, lo que nos sorprendi\u00f3 enormemente. Hab\u00edamos dudado de si se trataba de un problema con los materiales medicinales, pero el an\u00e1lisis posterior de los compuestos 1, 6, 7 y 8 aislados y reportados en este art\u00edculo se encontr\u00f3 en Angelica dahurica de tres or\u00edgenes diferentes, Hangbai, Chuanbai y Yubai, utilizando LC-MS. Esto indica que los compuestos 1, 6, 7 y 8 pueden ser detectados en Angelica dahurica de diferentes or\u00edgenes. Es posible que Bai Zhi contenga flavonoides. Los resultados de la investigaci\u00f3n han enriquecido la comprensi\u00f3n de la composici\u00f3n qu\u00edmica de Angelica dahurica y han proporcionado referencias importantes para su control de calidad y su desarrollo y utilizaci\u00f3n.<\/p>","protected":false},"excerpt":{"rendered":"
Research on Non coumarin Components in Bai Zhi Bai Zhi is a plant in the Umbelliferae family, Angelica dahurica (Fisch. ex Hoffm.) Benth Et Hook. f. or Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan’s dried roots. Spicy taste, warm nature. It has the effects of relieving […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\n
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Benth Et Hook. f. or Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan’s dried roots. Spicy taste, warm nature. 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