{"id":5066,"date":"2024-08-04T17:08:27","date_gmt":"2024-08-04T17:08:27","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5066"},"modified":"2024-08-04T17:08:27","modified_gmt":"2024-08-04T17:08:27","slug":"a-new-amide-alkaloid-in-the-root-of-fake-konjac","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/es\/un-nuevo-alcaloide-amida-en-la-raiz-del-falso-konjac\/","title":{"rendered":"Un nuevo alcaloide amida en la ra\u00edz del falso konjac"},"content":{"rendered":"

Un nuevo alcaloide amida en la ra\u00edz del falso konjac
\nPiper sarmentosum es una hierba perenne, rastrera, enraizada nudo por nudo, de la familia de las piper\u00e1ceas, que suele encontrarse en el sotobosque o en los humedales de los bordes de las carreteras. Se produce principalmente en provincias como Yunnan, Fujian y Guizhou, en China, y tambi\u00e9n se distribuye en India, Vietnam, Filipinas y Malasia. El falso konjac no s\u00f3lo tiene un gran valor medicinal, sino tambi\u00e9n ornamental, comestible y econ\u00f3mico. Seg\u00fan cl\u00e1sicos como \"Chinese Materia Medica\", el falso konjac tiene una naturaleza c\u00e1lida y un sabor amargo y acre. Sus ra\u00edces, hojas y frutos pueden utilizarse como medicina, con los efectos de calentar el medio y dispersar el fr\u00edo, disipar el viento y la humedad, reducir la hinchaz\u00f3n y el dolor. Se utiliza com\u00fanmente en el tratamiento del dolor de est\u00f3mago por fr\u00edo, el dolor de espalda reum\u00e1tico, el edema del embarazo y la hemorragia traum\u00e1tica, con importantes efectos terap\u00e9uticos. Las hojas falsas de konjac se utilizan y cultivan ampliamente como condimento en las regiones de Jiangsu, Zhejiang y Guangdong, en el sur de China, debido a su singular aroma acre.
\nEstudios farmacol\u00f3gicos modernos han demostrado que los extractos del falso konjac tienen una amplia gama de actividades biol\u00f3gicas, como propiedades antioxidantes, antiinflamatorias, antibacterianas, insecticidas, hipogluc\u00e9micas y neuroprotectoras. En la actualidad, la investigaci\u00f3n sobre la composici\u00f3n qu\u00edmica del falso konjac, tanto a escala nacional como internacional, se centra principalmente en las hojas y las partes a\u00e9reas, mientras que la investigaci\u00f3n sobre las ra\u00edces subterr\u00e1neas es relativamente escasa. Los componentes qu\u00edmicos aislados e identificados del falso konjac incluyen alcaloides, lignanos, flavonoides y esteroles. Nuestro grupo de investigaci\u00f3n aisl\u00f3 7 compuestos alcaloides de las hojas del falso konjac en la fase inicial, algunos de los cuales mostraron una buena actividad antibacteriana contra el Staphylococcus aureus. En una investigaci\u00f3n continua sobre la composici\u00f3n qu\u00edmica y la actividad biol\u00f3gica del falso konjac, se descubri\u00f3 que el extracto etan\u00f3lico 95% de la ra\u00edz del falso konjac puede aliviar los s\u00edntomas de la hinchaz\u00f3n del pie de rat\u00f3n inducida por carragenina y tiene un efecto dependiente de la dosis. Por lo tanto, se especula que el extracto contiene principios activos antiinflamatorios. Estudios relacionados han demostrado que los alcaloides son los principales ingredientes activos de la ra\u00edz del falso konjac. En este experimento se estudi\u00f3 la composici\u00f3n qu\u00edmica del extracto etan\u00f3lico 95% de la ra\u00edz del falso konjac, y se utiliz\u00f3 el modelo de inflamaci\u00f3n celular in vitro RAW264.7 inducida por LPS para examinar la actividad antiinflamatoria de los compuestos monom\u00e9ricos obtenidos. El objetivo es aclarar la composici\u00f3n qu\u00edmica y la base farmacol\u00f3gica relacionada de la ra\u00edz de falso konjac, con el fin de proporcionar una referencia para el desarrollo y la utilizaci\u00f3n racional de los recursos vegetales de falso konjac.<\/p>\n

\"\"\"\"\"\"
\nEn este experimento se utilizaron t\u00e9cnicas modernas de separaci\u00f3n cromatogr\u00e1fica y m\u00e9todos espectrosc\u00f3picos para aislar e identificar 10 compuestos alcaloides de la ra\u00edz del falso konjac. Entre ellos, el compuesto 1 es un nuevo alcaloide amida, y todos los compuestos excepto el compuesto 5 se a\u00edslan de esta planta por primera vez. La actividad antiinflamatoria de los compuestos aislados se evalu\u00f3 utilizando un modelo de inflamaci\u00f3n de macr\u00f3fagos RAW264.7 estimulado por LPS. Los resultados mostraron que los compuestos 1, 2, 4 y 10 ten\u00edan efectos inhibitorios sobre la producci\u00f3n de NO y no presentaban citotoxicidad significativa a las concentraciones ensayadas. Los resultados de este estudio enriquecen a\u00fan m\u00e1s la composici\u00f3n qu\u00edmica de la falsa ra\u00edz de konjac y aclaran preliminarmente la base de algunas sustancias activas antiinflamatorias en la falsa ra\u00edz de konjac, proporcionando cierta referencia y base te\u00f3rica para el futuro desarrollo y utilizaci\u00f3n de este recurso vegetal.<\/p>","protected":false},"excerpt":{"rendered":"

A new amide alkaloid in the root of fake konjac Piper sarmentosum is a perennial, creeping, node by node rooted herb of the Piperaceae family, commonly found in understory or roadside wetlands. It is mainly produced in provinces such as Yunnan, Fujian, and Guizhou in China, and is also distributed in India, Vietnam, the Philippines, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nA new amide alkaloid in the root of fake konjac - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/es\/un-nuevo-alcaloide-amida-en-la-raiz-del-falso-konjac\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new amide alkaloid in the root of fake konjac - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"A new amide alkaloid in the root of fake konjac Piper sarmentosum is a perennial, creeping, node by node rooted herb of the Piperaceae family, commonly found in understory or roadside wetlands. 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