{"id":7299,"date":"2024-08-06T19:19:43","date_gmt":"2024-08-06T19:19:43","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=7299"},"modified":"2024-08-06T19:19:43","modified_gmt":"2024-08-06T19:19:43","slug":"daphne-genkwa","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/daphne-genkwa\/","title":{"rendered":"En ny diterpenoidforbindelse af iridoid i blomsterknopperne af Daphne genkwa"},"content":{"rendered":"<p>En ny diterpenoidforbindelse af iridoid i blomsterknopperne af Daphne genkwa<br \/>\nDaphne Linn. er en l\u00f8vf\u00e6ldende busk, der tilh\u00f8rer familien Thymelaeaceae og sl\u00e6gten Daphne Sieb De t\u00f8rrede blomsterknopper af et Zucc., ogs\u00e5 kendt som medicinsk fiskegr\u00e6s, museblomst, legende fiskeblomst, hovedpineblomst, kedelig hovedblomst, Sichuan-morb\u00e6r og fiskegift, er hovedsageligt fordelt i forskellige provinser i Yangtze-flodbassinet og nogle omr\u00e5der i Yellow River-bassinet i Kina. I den kinesiske farmakop\u00e9 st\u00e5r der, at yuanhua har en bitter og skarp smag og en varm natur; Giftig, bruges til h\u00e6velser og fylde, hydrosalpinx i bryst og mave, ophobning af slim, tilbagesvaling af gas, hv\u00e6sende vejrtr\u00e6kning og hoste samt ugunstige tarmbev\u00e6gelser. Topisk behandling af fnat, alopeci og forfrysninger. Moderne unders\u00f8gelser af kemisk sammens\u00e6tning og farmakologisk aktivitet har vist, at Daphne genkwa indeholder rige kemiske strukturer som flavonoider, coumariner, lignin, diterpener, steroler osv. Det har en bred vifte af fysiologiske aktiviteter som antitumor, antiinflammatorisk, smertestillende, antikonvulsivt, livmoderstimulerende, fertilitetsh\u00e6mmende og immunregulerende. Der er dog relativt f\u00e5 unders\u00f8gelser og rapporter om topisk behandling af hudsygdomme som fnat, alopeci og forfrysninger. Da blomsterknopper fra traditionel kinesisk medicin kan have en vis resistens over for hudpatogene svampe, har forfatteren unders\u00f8gt den kemiske sammens\u00e6tning af 95%-ethanolekstraktet af blomsterknopper for at isolere og identificere naturlige blymolekyler med antihudpatogen svampeaktivitet, hvilket giver grundl\u00e6ggende data til udvikling og anvendelse af antihudpatogene l\u00e6gemidler til blomsterknopper fra traditionel kinesisk medicin.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7300\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-294.png\" alt=\"\" width=\"884\" height=\"722\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-294.png 884w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-294-768x627.png 768w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-294-882x720.png 882w\" sizes=\"(max-width: 884px) 100vw, 884px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7301\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-246.png\" alt=\"\" width=\"530\" height=\"269\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7302\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-231.png\" alt=\"\" width=\"529\" height=\"303\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7303\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-210.png\" alt=\"\" width=\"531\" height=\"377\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7304\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-190.png\" alt=\"\" width=\"807\" height=\"287\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-190.png 807w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-190-768x273.png 768w\" sizes=\"(max-width: 807px) 100vw, 807px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-7305\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-173.png\" alt=\"\" width=\"881\" height=\"267\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-173.png 881w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-173-768x233.png 768w\" sizes=\"(max-width: 881px) 100vw, 881px\" \/><br \/>\nHudsvampesygdomme er en global infektionssygdom, og de fugtige og varme regioner i det sydlige Kina som Guangdong, Hainan, Fujian og Hong Kong er h\u00f8jrisikoomr\u00e5der for hudsvampesygdomme. Kina har rigelige ressourcer af traditionel kinesisk medicin, og det er n\u00f8dvendigt at s\u00f8ge efter og udvikle nye antifungale aktive stoffer eller l\u00e6gemidler fra kinesiske medicinske materialer. Denne unders\u00f8gelse brugte kromatografiske separationsteknikker og metoder til identifikation af naturproduktstrukturer til at isolere og identificere to diterpenoidforbindelser af naringenintypen fra blomsterknopperne af Daphne genkwa, som har evnen til at behandle fnat og alopecia. En af dem er en ny forbindelse; Forbindelsens h\u00e6mmende aktivitet mod Microsporum canis, Trichophyton rubrum, Trichophyton rubrum og Malassezia blev bestemt ved hj\u00e6lp af MIC-metoden. Det viste sig, at forbindelserne 1 og 2 udviste st\u00e6rk h\u00e6mmende aktivitet mod Trichophyton rubrum og Trichophyton rubrum. Denne artikel beriger yderligere den kemiske sammens\u00e6tning af yuanhua-blomsterknopper og opdager deres in vitro-svampeaktivitet og akkumulerer grundl\u00e6ggende data til ekstern anvendelse og udvikling af yuanhua-blomsterknopper.<\/p>","protected":false},"excerpt":{"rendered":"<p>A new diterpenoid compound of iridoid in the flower buds of Daphne genkwa Daphne Linn. is a deciduous shrub belonging to the Thymelaeaceae family and the genus Daphne Sieb The dried flower buds of et Zucc., also known as medicinal fish grass, mouse flower, playful fish flower, headache flower, dull head flower, Sichuan mulberry, and [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A new diterpenoid compound of iridoid in the flower buds of Daphne genkwa - 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