{"id":6785,"date":"2024-08-06T14:41:21","date_gmt":"2024-08-06T14:41:21","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=6785"},"modified":"2024-08-06T14:41:21","modified_gmt":"2024-08-06T14:41:21","slug":"mangifera","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/mangifera\/","title":{"rendered":"Analyse af kemisk sammens\u00e6tning af mangokerne baseret p\u00e5 UPLC-Q-TOF-MS\/MS"},"content":{"rendered":"<p>Analyse af kemisk sammens\u00e6tning af mangokerne baseret p\u00e5 UPLC-Q-TOF-MS\/MS<br \/>\nMangifera indica L. er en planteart i familien Anacardiaceae, og dens frugt, mango, er den mest handlede, eksporterede og konsumerede tropiske frugt p\u00e5 verdensplan. Mangokerner, som udg\u00f8r 20% til 60% af mangoens samlede v\u00e6gt, bliver ofte kasseret som affald. Men mangokerner er et af de mest anvendte l\u00e6gemidler i tibetansk og mongolsk medicin. I \"Chinese Materia Medica: Mongolian Medicine Volume\" st\u00e5r der, at de fremmer ford\u00f8jelsen, reducerer slim og fremmer qi-cirkulationen. De bruges mod madstagnation, appetitl\u00f8shed, hoste, brok, orkitis og andre tilstande. I \"Drug Standards of the Ministry of Health - Tibetan Medicine\" st\u00e5r der, at den virker n\u00e6rende p\u00e5 yin og nyre og ofte bruges mod nyremangel. Forskning har vist, at de kemiske komponenter i mangokerne hovedsageligt er polyfenoler, flavonoider, alkaloider og saponiner, som har betydelig antioxidantaktivitet og kan bruges som erstatning for kakaosm\u00f8r i kosmetik, f\u00f8devarer, l\u00e6gemidler og andre omr\u00e5der. Men det farmakologiske grundlag for mangofr\u00f8, der bruges i tibetansk og mongolsk medicin til behandling af sygdomme som koststagnation og nyremangel, er endnu ikke klart. Derfor er der behov for yderligere omfattende og systematisk kvalitativ analyse af den kemiske sammens\u00e6tning af mangofr\u00f8.<\/p>\n<p>Traditionelle kemiske analysemetoder, fra ekstraktion og adskillelse af kemiske komponenter til strukturel identifikation, er ofte tidskr\u00e6vende og arbejdskr\u00e6vende, og den strukturelle analyse af de opn\u00e5ede komponenter er ogs\u00e5 meget vanskelig. UPLC-Q-TOF-MS\/MS-teknologien (ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry) har fordelene ved h\u00f8j separationsevne, h\u00f8j f\u00f8lsomhed og h\u00f8j opl\u00f8sning, som hurtigt kan opn\u00e5 analyse af kemiske l\u00e6gemiddelkomponenter. Den anvendes i stigende grad inden for kvalitativ analyse af kemiske komponenter i naturlige l\u00e6gemidler. For yderligere at belyse det farmakologiske stofgrundlag for mangofr\u00f8 har denne unders\u00f8gelse til hensigt at bruge UPLC-Q-TOF-MS \/ MS til hurtig kvalitativ analyse af de kemiske komponenter i mangofr\u00f8 for at give reference til efterf\u00f8lgende forskning i mangofr\u00f8 og den rationelle udvikling og anvendelse af ressourcer.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6786\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-256.png\" alt=\"\" width=\"662\" height=\"893\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-256.png 662w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/1-256-534x720.png 534w\" sizes=\"(max-width: 662px) 100vw, 662px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6787\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-28.jpg\" alt=\"\" width=\"665\" height=\"812\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-28.jpg 665w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/2-28-590x720.jpg 590w\" sizes=\"(max-width: 665px) 100vw, 665px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6788\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-201.png\" alt=\"\" width=\"663\" height=\"812\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-201.png 663w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/3-201-588x720.png 588w\" sizes=\"(max-width: 663px) 100vw, 663px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6789\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-179.png\" alt=\"\" width=\"663\" height=\"789\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-179.png 663w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/4-179-605x720.png 605w\" sizes=\"(max-width: 663px) 100vw, 663px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6790\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-163.png\" alt=\"\" width=\"662\" height=\"798\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-163.png 662w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/5-163-597x720.png 597w\" sizes=\"(max-width: 662px) 100vw, 662px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6791\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-14.jpg\" alt=\"\" width=\"662\" height=\"791\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-14.jpg 662w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/6-14-603x720.jpg 603w\" sizes=\"(max-width: 662px) 100vw, 662px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6792\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-135.png\" alt=\"\" width=\"660\" height=\"802\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-135.png 660w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/7-135-593x720.png 593w\" sizes=\"(max-width: 660px) 100vw, 660px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6793\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/8-123.png\" alt=\"\" width=\"661\" height=\"308\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6794\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/9-115.png\" alt=\"\" width=\"665\" height=\"299\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6795\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/10-92.png\" alt=\"\" width=\"661\" height=\"431\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6796\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/11-85.png\" alt=\"\" width=\"663\" height=\"417\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6797\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/12-68.png\" alt=\"\" width=\"661\" height=\"396\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6798\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/13-57.png\" alt=\"\" width=\"660\" height=\"429\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6799\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-44.png\" alt=\"\" width=\"328\" height=\"137\" srcset=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-44.png 328w, https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/14-44-325x137.png 325w\" sizes=\"(max-width: 328px) 100vw, 328px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6800\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/15-33.png\" alt=\"\" width=\"661\" height=\"365\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6801\" src=\"https:\/\/longchangextracts.com\/wp-content\/uploads\/2024\/08\/16-25.png\" alt=\"\" width=\"658\" height=\"379\" \/>I dagligdagen bliver mangokerner ofte kasseret som et biprodukt af mangoforarbejdning, hvilket resulterer i ressourcespild og milj\u00f8forurening. For at forbedre v\u00e6rdien af mangokerner brugte denne unders\u00f8gelse derfor UPLC-Q-TOFMS\/MS-teknologi til systematisk og omfattende at analysere de kemiske komponenter i alkoholekstraktet af mangokerner. At skabe et grundlag for udvikling af innovative funktionelle f\u00f8devarer og dybdeg\u00e5ende forskning inden for omr\u00e5der som medicin til mango kerner.<br \/>\nFor bedre at kunne udforske de potentielle medicinske stoffer i mango kerner, udf\u00f8rte denne unders\u00f8gelse en dybdeg\u00e5ende analyse af de kemiske komponenter i mango kerner ved at \u00e6ndre den mobile fase og optimere massespektrometri parametre baseret p\u00e5 identifikation af polyphenoliske stoffer af tidligere forskere. Med hensyn til de organiske faser af methanol og acetonitril og de vandige faser af vand, 0,1% myresyrevand og 0,2% myresyrevand blev de mobile faser unders\u00f8gt og i sidste ende bestemt til at v\u00e6re acetonitril og 0,1% myresyrevand. Baseret p\u00e5 de kendte forbindelser gallussyre, 1,2,3,6-tetragalloylglukose, luteolin, quercetin og mangiferin i mangokerne blev der udf\u00f8rt parameteroptimering for at opn\u00e5 de optimale fragmentioner med tilsvarende strukturer. Ved at kombinere retentionstid, pr\u00e6cis molekylv\u00e6gt, fragmentioner fra sekund\u00e6r massespektrometri og relevant litteratur blev der identificeret i alt 135 bioaktive stoffer fra mangokerne, herunder 47 gallussyretanniner, 47 flavonoider, 30 organiske syrer, 3 coumariner og 8 iridoidglykosider. Blandt dem blev coumariner og iridoidglykosider identificeret for f\u00f8rste gang fra mangokerner. P\u00e5 nuv\u00e6rende tidspunkt fokuserer forskningen hovedsageligt p\u00e5 de polyfenoliske stoffer i mangokerne, og unders\u00f8gelsen af de bioaktive stoffer i mangokerne er ikke klar nok. Derfor bruger dette eksperiment UPLC-Q-TOF-MS\/MS til systematisk og omfattende at analysere de kemiske komponenter i mango kerner, hvilket giver reference og grundlag for at afsl\u00f8re virkningsmekanismen for komplekse komponenter i mango kerner og yderligere udvikling.<\/p>","protected":false},"excerpt":{"rendered":"<p>Chemical Composition Analysis of Mango Kernel Based on UPLC-Q-TOF-MS\/MS Mangifera indica L. is a plant species in the family Anacardiaceae, and its fruit, mango, is the most traded, exported, and consumed tropical fruit worldwide. Mango kernels, which account for 20% to 60% of the total weight of mangoes, are often discarded as waste. However, mango [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chemical Composition Analysis of Mango Kernel Based on UPLC-Q-TOF-MS\/MS - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/da\/mangifera\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemical Composition Analysis of Mango Kernel Based on UPLC-Q-TOF-MS\/MS - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Chemical Composition Analysis of Mango Kernel Based on UPLC-Q-TOF-MS\/MS Mangifera indica L. is a plant species in the family Anacardiaceae, and its fruit, mango, is the most traded, exported, and consumed tropical fruit worldwide. 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Mango kernels, which account for 20% to 60% of the total weight of mangoes, are often discarded as waste. 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