{"id":5435,"date":"2024-08-04T18:58:34","date_gmt":"2024-08-04T18:58:34","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5435"},"modified":"2024-08-04T18:58:34","modified_gmt":"2024-08-04T18:58:34","slug":"research-on-non-coumarin-components-in-bai-zhi","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/research-on-non-coumarin-components-in-bai-zhi\/","title":{"rendered":"Forskning i ikke-kumarinkomponenter i Bai Zhi"},"content":{"rendered":"

Forskning i ikke-kumarinkomponenter i Bai Zhi
\nBai Zhi er en plante i sk\u00e6rmplantefamilien, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. eller Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan's t\u00f8rrede r\u00f8dder. Krydret smag, varm natur. Den virker symptomlindrende, fordriver kulde, fordriver vind og lindrer smerter, fremmer n\u00e6se\u00e5bning, t\u00f8rrer fugt og stopper b\u00e6lter samt reducerer h\u00e6velse og pus. I klinisk praksis bruges den til at behandle fork\u00f8lelse, hovedpine, smerter i \u00f8jenbrynene, tilstoppet n\u00e6se, l\u00f8bende n\u00e6se, tilstoppet n\u00e6se, bihulebet\u00e6ndelse, tandpine, udfl\u00e5d fra skeden, \u00f8mme og smertefulde s\u00e5r osv. Angelica dahurica er et af de almindeligt anvendte medicinske materialer i klinisk praksis. If\u00f8lge statistikker er der indtil nu inkluderet 565 sorter af traditionelle kinesiske patentl\u00e6gemidler og enkle pr\u00e6parater, der indeholder Angelica dahurica, i den traditionelle kinesiske receptdatabase for patentl\u00e6gemidler og enkle pr\u00e6parater, og 1836 recepter, der indeholder Angelica dahurica, er inkluderet i receptdatabasen for traditionel kinesisk medicin. For at belyse det farmakologiske stofgrundlag har forskere isoleret og identificeret en r\u00e6kke kumarinkomponenter fra Bai Zhi. Derudover er der litteraturrapporter om, at Bai Zhi indeholder rigeligt med flavonoider, men der er i \u00f8jeblikket ingen relevante rapporter om isolering og oprensning af flavonoidmonomerer fra Bai Zhi. I den indledende systematiske unders\u00f8gelse af den kemiske sammens\u00e6tning af Angelica dahurica fandt forskerholdet, at Angelica dahurica ud over en stor m\u00e6ngde kumarinkomponenter ogs\u00e5 kan indeholde ikke-kumarinkomponenter som alkaloider og flavonoider. Ved hj\u00e6lp af LC-MS-styret separationsteknologi blev flere strukturelt nye coumarindimerer opdaget fra Angelica dahurica, og de h\u00f8jpol\u00e6re dele af ethanoludtr\u00e6kket af Hangbai dahurica blev unders\u00f8gt. Seksten pyrrolalkaloider blev med succes isoleret og identificeret. Denne artikel rapporterer endvidere om isolering og identifikation af ikke-kumarinforbindelser fra de vandopl\u00f8selige dele af Angelica dahurica.<\/p>\n

\"\"I litteraturen om den kemiske sammens\u00e6tning af Angelica dahurica antages det generelt, at de vigtigste kemiske komponenter i Angelica dahurica er kumarinforbindelser, mens der kun er f\u00e5 rapporter om ikke-kumarinforbindelser i Angelica dahurica. Lu et al. isolerede og identificerede engang et pyrrolisk alkaloid, coumarin, fra Angelica dahurica. I vores systematiske unders\u00f8gelse af Angelica dahurica isolerede vores forskningsgruppe ikke kun en stor m\u00e6ngde coumariner og coumarindimerer, men isolerede ogs\u00e5 16 pyrroliske alkaloider fra Angelica dahurica, hvilket berigede vores forst\u00e5else af dens kemiske sammens\u00e6tning. I den videre forskning i den kemiske sammens\u00e6tning af Bai Zhi blev der uventet isoleret 18 komponenter, der ikke er coumariner, som rapporteret i denne artikel. Ud over det tidligere rapporterede Jin Qian Cao-alkaloid blev de andre 17 ikke-kumarinkomponenter, herunder 9 flavonoider, 5 lignaner, 2 simple phenolestere og 1-H-imidazo [4,5-d] pyridazin-2-amin, alle isoleret fra Bai Zhi for f\u00f8rste gang. Forbindelserne 3 og 18 har visse h\u00e6mmende virkninger p\u00e5 zymosan-induceret frigivelse af superoxid fra neutrofiler, mens forbindelserne 1 og 18 har h\u00e6mmende virkninger p\u00e5 frigivelsen af NO-aktivitet fra RAW 264.7-celler. Det er v\u00e6rd at bem\u00e6rke, at selvom der har v\u00e6ret flere litteraturrapporter om tilstedev\u00e6relsen af flavonoider i Angelica dahurica, er de alle forel\u00f8bige rapporter om bestemmelsen af det samlede flavonoidindhold. I \u00f8jeblikket er der ingen rapporter om isolering af monomere flavonoider fra Angelica dahurica. Men i denne unders\u00f8gelse blev der for f\u00f8rste gang opn\u00e5et flere flavonoider og flavonoidglykosidmonomerer fra Angelica dahurica, hvilket overraskede os meget. Vi var i tvivl om, hvorvidt det var et problem med de medicinske materialer, men yderligere analyse af forbindelserne 1, 6, 7 og 8, der blev isoleret og rapporteret i denne artikel, blev fundet i Angelica dahurica fra tre forskellige oprindelser, Hangbai, Chuanbai og Yubai, ved hj\u00e6lp af LC-MS. Dette indikerer, at forbindelserne 1, 6, 7 og 8 kan p\u00e5vises i Angelica dahurica fra forskellige oprindelser. Bai Zhi kan faktisk indeholde flavonoider. Forskningsresultaterne har beriget forst\u00e5elsen af den kemiske sammens\u00e6tning af Angelica dahurica og givet vigtige referencer til kvalitetskontrol, udvikling og anvendelse af Angelica dahurica.<\/p>","protected":false},"excerpt":{"rendered":"

Research on Non coumarin Components in Bai Zhi Bai Zhi is a plant in the Umbelliferae family, Angelica dahurica (Fisch. ex Hoffm.) Benth Et Hook. f. or Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan’s dried roots. Spicy taste, warm nature. It has the effects of relieving […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nResearch on Non coumarin Components in Bai Zhi - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/da\/research-on-non-coumarin-components-in-bai-zhi\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research on Non coumarin Components in Bai Zhi - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Research on Non coumarin Components in Bai Zhi Bai Zhi is a plant in the Umbelliferae family, Angelica dahurica (Fisch. ex Hoffm.) Benth Et Hook. f. or Hangbaizhi A dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. var. formosana (Boiss.) Shan et Yuan’s dried roots. Spicy taste, warm nature. 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