{"id":5277,"date":"2024-08-04T18:08:09","date_gmt":"2024-08-04T18:08:09","guid":{"rendered":"https:\/\/longchangextracts.com\/?p=5277"},"modified":"2024-08-04T18:08:09","modified_gmt":"2024-08-04T18:08:09","slug":"grass-fruit-on-%ce%b1-glucosidase","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/graesfrugt-pa-\u03b1-glucosidase\/","title":{"rendered":"Unders\u00f8gelse af den kemiske sammens\u00e6tning og h\u00e6mmende aktivitet af gr\u00e6sfrugter p\u00e5 \u03b1-glucosidase"},"content":{"rendered":"

Unders\u00f8gelse af den kemiske sammens\u00e6tning og h\u00e6mmende aktivitet af gr\u00e6sfrugter p\u00e5 \u03b1-glucosidase
\nAmomum tsao ko Crevost&Lemarie er fler\u00e5rige urteagtige planter af ingef\u00e6rfamilien og kardemommesl\u00e6gten, der hovedsageligt er udbredt i provinser som Yunnan, Guangxi og Guizhou i Kina. Frugter, der bruges som medicin, har til form\u00e5l at t\u00f8rre fugt, styrke milten, fjerne slim og opfange malaria; den kan ogs\u00e5 bruges som krydderi til at udtr\u00e6kke aromatiske olier og er en type medicinsk og spiselig sort med dobbelt anvendelse. Som en almindelig medicinsk og spiselig sort i Kina er den kemiske sammens\u00e6tning og de farmakologiske virkninger af gr\u00e6sfrugt blevet unders\u00f8gt i vid udstr\u00e6kning. Med hensyn til kemisk sammens\u00e6tning omfatter den ud over flygtige oliekomponenter hovedsageligt flavonoider, fenoler og diphenylheptaner. Blandt dem er flavonoider mest rapporteret for deres antiinflammatoriske og antioxidante aktiviteter, fenoler er mest rapporteret for deres antioxidante aktiviteter, og diphenylheptaner er bredt rapporteret for deres antitumor- og \u03b1-glucosidaseh\u00e6mmende aktiviteter.<\/p>\n

Diabetes er en metabolisk sygdom, der er kendetegnet ved hyperglyk\u00e6mi og flere komplikationer. I de senere \u00e5r er det blevet den tredje \"sundhedsdr\u00e6ber\" efter kardiovaskul\u00e6re og cerebrovaskul\u00e6re sygdomme og kr\u00e6ft. \u03b1-glukosidaseh\u00e6mmer kan kontrollere udviklingen af diabetes, is\u00e6r forekomsten af komplikationer, ved at reducere toppen af postprandial blodsukker. Det er et lovende l\u00e6gemiddel til behandling af diabetes. Acarbose, voglibose og miglitol er i \u00f8jeblikket de mest anvendte \u03b1-glukosidaseh\u00e6mmere i klinisk praksis, men de er dyre, har bivirkninger s\u00e5som forstyrrelser i ford\u00f8jelseskanalen, hypoglyk\u00e6mi, der f\u00f8rer til chok, og kan ikke effektivt behandle diabeteskomplikationer. Det er af stor betydning at udforske nye \u03b1-glucosidaseh\u00e6mmere. Forskning har vist, at det t\u00f8rre pulver og ekstrakt af gr\u00e6sfrugt har hypoglyk\u00e6miske funktioner og h\u00e6mmer \u03b1-glucosidase-relaterede aktiviteter, men der er ingen relevant unders\u00f8gelse af de hypoglyk\u00e6miske virkninger af dets monomere komponenter. Denne unders\u00f8gelse ekstraherede og adskilte systematisk gr\u00e6sfrugter og fandt ud af, at de monomere komponenter berigede artens kemiske mangfoldighed. Der blev ogs\u00e5 fundet forbindelser, som h\u00e6mmer alfa-glucosidase, hvilket forventes at give nye ideer til den kliniske brug af traditionel kinesisk medicin.<\/p>\n

\"\"\"\"\"\"\"\"
\nI denne unders\u00f8gelse blev 11 forbindelser isoleret fra frugten af traditionel kinesisk medicin gr\u00e6sfrugt. Forbindelse 1 er en phenolforbindelse, som f\u00f8rst blev rapporteret som et naturprodukt. Forbindelse 2, 8 og 9 er phenol- og fedtsyreforbindelser, der er isoleret fra kardemommesl\u00e6gten for f\u00f8rste gang; Gennem test af \u03b1-glucosidaseh\u00e6mmende aktivitet blev det konstateret, at to diphenylheptanforbindelser har st\u00e6rkere aktivitet end det markedsf\u00f8rte l\u00e6gemiddel acarbose. Tidligere unders\u00f8gelser har vist, at alkoholekstraktet af gr\u00e6sfrugt har h\u00e6mmende aktivitet mod \u03b1-glucosidase, mens de andre monomere komponenter i denne unders\u00f8gelse ikke viste signifikant h\u00e6mmende aktivitet. Det spekuleres i, at disse diphenylheptanforbindelser er et af de materielle grundlag for den hypoglyk\u00e6miske virkning af gr\u00e6sfrugt in vitro. \u03b1-glukosidaseh\u00e6mmer har v\u00e6ret meget omtalt i de senere \u00e5r som et l\u00e6gemiddel til klinisk behandling af type 2-diabetes. Denne unders\u00f8gelse beriger ikke kun mangfoldigheden af komponenter i Caoguo, en traditionel kinesisk medicin, men forventes ogs\u00e5 yderligere at opdage en ny klinisk anvendelsesvej for Caoguo, en traditionel kinesisk medicin, ved at h\u00e6mme aktiviteten af \u03b1-glucosidase med dens monomere komponenter.<\/p>","protected":false},"excerpt":{"rendered":"

Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 – Glucosidase Amomum tsao ko Crevost&Lemarie are perennial herbaceous plants of the ginger family and cardamom genus, mainly distributed in provinces such as Yunnan, Guangxi, and Guizhou in China. Fruits used as medicine have the functions of drying dampness, invigorating the spleen, […]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"\nStudy on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 - Glucosidase - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/da\/graesfrugt-pa-\u03b1-glucosidase\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 - Glucosidase - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"Study on the Chemical Composition and Inhibition Activity of Grass Fruit on \u03b1 – Glucosidase Amomum tsao ko Crevost&Lemarie are perennial herbaceous plants of the ginger family and cardamom genus, mainly distributed in provinces such as Yunnan, Guangxi, and Guizhou in China. 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