{"id":3454,"date":"2024-07-19T06:12:52","date_gmt":"2024-07-19T06:12:52","guid":{"rendered":"https:\/\/pharm.sinocurechem.com\/?p=3454"},"modified":"2024-07-19T06:12:52","modified_gmt":"2024-07-19T06:12:52","slug":"o-anisidine-2-methoxyaniline-chemical-properties-synthesis-applications-and-safety-considerations","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/o-anisidin-2-methoxyanilin-kemiske-egenskaber-syntese-anvendelser-og-sikkerhedsovervejelser\/","title":{"rendered":"o-Anisidin (2-Methoxyanilin): Kemiske egenskaber, syntese, anvendelser og sikkerhedsovervejelser"},"content":{"rendered":"<p class=\"MsoNormal\" style=\"text-align: center;\" align=\"center\"><b><i><span style=\"font-family: Georgia; font-size: 12pt;\">o-Anisidin (2-Methoxyanilin): Kemiske egenskaber, syntese, anvendelser og sikkerhedsovervejelser<\/span><\/i><\/b><b><i><\/i><\/b><\/p>\n<p class=\"MsoNormal\" style=\"text-align: center;\" align=\"center\"><b><i><span style=\"font-family: Georgia; font-size: 12pt;\">o-Anisidin CAS 90-04-0<\/span><\/i><\/b><b><i><\/i><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin, ogs\u00e5 kendt som 2-methoxyanilin, er en aromatisk amin med den kemiske formel C7H9NO. Det er en farvel\u00f8s til gullig v\u00e6ske med en karakteristisk lugt, der prim\u00e6rt bruges som mellemprodukt i syntesen af forskellige farvestoffer, pigmenter og l\u00e6gemidler.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l1 level1 lfo1;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 14.0000pt; mso-font-kerning: 1.0000pt;\">1.\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 14pt;\">Kemiske egenskaber<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">IUPAC-navn: 2-Methoxyanilin<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">CAS-nummer: 90-04-0<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Molekyl\u00e6r formel: C7H9NO<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Molekylv\u00e6gt: 123,15 g\/mol<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Struktur: Den kemiske struktur best\u00e5r af en benzenring, der er substitueret med en methoxygruppe (-OCH3) i ortho-position og en aminogruppe (-NH2) i para-position.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Udseende: Farvel\u00f8s til gullig v\u00e6ske<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Kogepunkt: 218-219\u00b0C<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Smeltepunkt: -2\u00b0C<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Massefylde: 1,088 g\/cm\u00b3 ved 20\u00b0C<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Opl\u00f8selighed: Opl\u00f8selig i organiske opl\u00f8sningsmidler som ethanol, ether og chloroform; let opl\u00f8selig i vand.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l1 level1 lfo1;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 14.0000pt; mso-font-kerning: 1.0000pt;\">2.\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 14pt;\">Syntese<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l0 level1 lfo2;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">1)\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 12pt;\">Reduktion af o-nitroanisol<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">En af de prim\u00e6re metoder til at syntetisere o-anisidin er reduktion af o-nitroanisol (2-nitroanisol). Denne proces kan udf\u00f8res ved hj\u00e6lp af forskellige reduktionsmidler, der hver is\u00e6r giver forskellige fordele afh\u00e6ngigt af syntesens omfang og specifikke krav.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Katalytisk hydrogenering: Denne metode indeb\u00e6rer reduktion af o-nitroanisol ved hj\u00e6lp af brintgas i n\u00e6rv\u00e6r af en passende katalysator. Almindelige katalysatorer omfatter palladium p\u00e5 kulstof (Pd\/C), platin (Pt) eller Raney-nikkel.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Reaktionsbetingelser: Reaktionen udf\u00f8res typisk i et passende opl\u00f8sningsmiddel som f.eks. ethanol, methanol eller eddikesyre. Blandingen uds\u00e6ttes for brintgas under kontrolleret tryk og temperatur.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Fordele: Katalytisk hydrogenering giver et h\u00f8jt udbytte af o-anisidin med minimale biprodukter. Processen er effektiv og kan opskaleres til industriel produktion.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Mekanisme: Nitrogruppen (-NO2) i o-nitroanisol reduceres til en aminogruppe (-NH2) gennem successive trin, der involverer dannelse af mellemliggende nitroso- og hydroxylaminarter.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Kemisk reduktion: Alternativt kan o-nitroanisol reduceres ved hj\u00e6lp af kemiske reduktionsmidler s\u00e5som jernsp\u00e5ner i tilstedev\u00e6relse af saltsyre (Bechamp-reduktion), zinkst\u00f8v eller natriumsulfid.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Bechamp-reduktion: Jernsp\u00e5ner og saltsyre reducerer o-nitroanisol til o-anisidin. Denne metode er historisk vigtig og bruges stadig i visse anvendelser.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Fordele: Kemiske reduktionsmetoder er omkostningseffektive og egnede til syntese i stor skala, is\u00e6r i milj\u00f8er, hvor katalytisk hydrogeneringsinfrastruktur ikke er tilg\u00e6ngelig.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l0 level1 lfo2;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">2)\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 12pt;\">Methylering af anilin<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">En anden tilgang til at syntetisere o-anisidin involverer methylering af anilin (phenylamin) efterfulgt af selektiv demethylering.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Methylering med dimethylsulfat: Anilin kan methyleres med dimethylsulfat for at danne N-methylanilin og efterf\u00f8lgende N,N-dimethylanilin.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Reaktionsbetingelser: Anilin reageres med dimethylsulfat i n\u00e6rv\u00e6r af en base som f.eks. natriumhydroxid eller kaliumcarbonat. Reaktionen foreg\u00e5r typisk i et organisk opl\u00f8sningsmiddel som acetone eller dimethylformamid (DMF).<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Demethylering: Den resulterende N,N-dimethylanilin uds\u00e6ttes for selektiv demethylering for at give o-anisidin. Dette trin kan opn\u00e5s ved hj\u00e6lp af reagenser som brintoverilte (HBr) eller bortribromid (BBr3).<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l0 level1 lfo2;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">3)\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 12pt;\">Direkte \u00e6terificering<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">En mindre almindelig, men brugbar metode til at syntetisere o-anisidin involverer direkte \u00e6terificering af anilin med methanol eller dimethylether under sure forhold.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">\u00c6terificeringsproces: Anilin oms\u00e6ttes med methanol i n\u00e6rv\u00e6r af en syrekatalysator som f.eks. svovlsyre eller saltsyre.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Reaktionsbetingelser: Blandingen opvarmes under tilbagesvaling for at fremme dannelsen af methoxygruppen (-OCH3) i ortho-position i forhold til aminogruppen (-NH2).<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Fordele: Denne metode giver en ligetil vej til o-anisidin, selvom den kan kr\u00e6ve streng kontrol af reaktionsbetingelserne for at minimere sidereaktioner og opn\u00e5 h\u00f8j selektivitet.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l0 level1 lfo2;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">4)\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 12pt;\">Nitrerings- og reduktionssekvens<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">En mere kompliceret syntetisk rute involverer nitrering af anisol efterfulgt af selektiv reduktion.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Nitrering af anisol: Anisol (methoxybenzen) nitreres ved hj\u00e6lp af en blanding af koncentreret salpetersyre og svovlsyre for at give en blanding af nitroanisol-isomerer.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Reaktionsbetingelser: Nitreringen udf\u00f8res ved kontrollerede temperaturer for at fremme dannelsen af ortho-nitroanisol-isomeren.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Adskillelse: Isomererne adskilles ved hj\u00e6lp af teknikker som fraktioneret destillation eller kromatografi.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Reduktion til o-anisidin: Ortho-nitroanisolen reduceres derefter selektivt til o-anisidin ved hj\u00e6lp af katalytisk hydrogenering eller kemiske reduktionsmetoder, som beskrevet tidligere.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l1 level1 lfo1;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 14.0000pt; mso-font-kerning: 1.0000pt;\">3.\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 14pt;\">Anvendelser<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Farve- og pigmentindustrien:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin er et afg\u00f8rende mellemprodukt i syntesen af forskellige farvestoffer og pigmenter, is\u00e6r:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Azofarvestoffer: Bruges i vid udstr\u00e6kning i tekstil-, l\u00e6der- og papirindustrien<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) Triphenylmethan-farvestoffer: Anvendes i bl\u00e6k, maling og biologiske bejdser<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Indigofarvestoffer: Bruges i denim og andre tekstiler<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">d) Kinolinfarvestoffer: Anvendes i forskellige industri- og forbrugerprodukter<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Den farmaceutiske industri:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin fungerer som udgangsmateriale eller mellemprodukt i syntesen af:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Smertestillende og anti-inflammatorisk medicin<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) Antihypertensive midler<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Antihistaminer<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">d) Lokalbed\u00f8velse<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">e) Antimikrobielle forbindelser<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Den agrokemiske sektor:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Forbindelsen bruges i produktionen af:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Herbicider: Som forl\u00f8ber i triazinbaserede herbicider<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) Insekticider: Is\u00e6r i syntesen af nogle organofosfatforbindelser<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Svampemidler: Som mellemprodukt i visse azolbaserede fungicider<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Smags- og duftindustrien:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin er en vigtig forl\u00f8ber i syntesen af:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Vanillin: Den prim\u00e6re komponent i vaniljesmag<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) Ethylvanillin: En mere potent syntetisk vaniljearoma<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Guaiacol: Bruges i produktionen af forskellige smags- og duftstoffer<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Polymer- og gummiindustrien:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Forbindelsen finder anvendelse i:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Antioxidanter til gummi og plast<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) H\u00e6rdningsmidler til epoxyharpikser<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Stabilisatorer i polymerproduktion<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Korrosionsh\u00e6mmere:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidinderivater bruges som korrosionsh\u00e6mmere i:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Industrielle k\u00f8lesystemer<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) Olie- og gasr\u00f8rledninger<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Metalforarbejdende industrier<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Forskning og analytisk kemi:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin fungerer som:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Et reagens i forskellige organiske synteser<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) En standard inden for analytisk kemi til metodeudvikling og validering<\/span><\/p>\n<p class=\"MsoNormal\"><b><span style=\"font-family: Georgia; font-size: 12pt;\">Specialkemikalier:<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Forbindelsen bruges i produktionen af:<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">a) Optiske blegemidler til tekstiler og papir<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">b) UV-absorbenter til plast og kosmetik<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">c) Antioxidanter til br\u00e6ndstoffer og sm\u00f8remidler<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l1 level1 lfo1;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 14.0000pt; mso-font-kerning: 1.0000pt;\">4.\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 14pt;\">Sikkerhed<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">o-Anisidin er klassificeret som et farligt stof p\u00e5 grund af dets toksikologiske egenskaber. Det kan optages gennem huden, ind\u00e5nding eller indtagelse og for\u00e5rsage forskellige helbredseffekter.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Sundhedsfarer: Uds\u00e6ttelse for o-anisidin kan for\u00e5rsage irritation af hud, \u00f8jne og luftveje. Langvarig eksponering kan f\u00f8re til meth\u00e6moglobin\u00e6mi, en tilstand, hvor h\u00e6moglobin ikke er i stand til effektivt at frigive ilt til kroppens v\u00e6v. Det betragtes ogs\u00e5 som et potentielt kr\u00e6ftfremkaldende stof.<\/span><\/p>\n<p class=\"MsoNormal\" style=\"margin-left: 21.2500pt; mso-para-margin-left: 0.0000gd; text-indent: -21.2500pt; mso-char-indent-count: 0.0000; mso-list: l1 level1 lfo1;\"><!-- [if !supportLists]--><span style=\"font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-weight: bold; font-size: 14.0000pt; mso-font-kerning: 1.0000pt;\">5.\u00a0<\/span><!--[endif]--><b><span style=\"font-family: Georgia; font-size: 14pt;\">H\u00e5ndtering og opbevaring<\/span><\/b><b><\/b><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Personlige v\u00e6rnemidler (PPE): Ved h\u00e5ndtering af o-anisidin skal der b\u00e6res passende personlige v\u00e6rnemidler s\u00e5som handsker, beskyttelsesbriller og kittel for at minimere eksponeringen.<\/span><\/p>\n<p class=\"MsoNormal\"><span style=\"mso-spacerun: 'yes'; font-family: Georgia; mso-fareast-font-family: \u5b8b\u4f53; font-size: 12.0000pt; mso-font-kerning: 1.0000pt;\">Opbevaring: Det skal opbevares p\u00e5 et k\u00f8ligt, godt ventileret sted v\u00e6k fra ant\u00e6ndelseskilder. Beholdere skal v\u00e6re t\u00e6t forseglede for at forhindre l\u00e6kage og forurening.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>o-Anisidine (2-Methoxyaniline): Chemical Properties, Synthesis, Applications, and Safety Considerations o-Anisidine CAS 90-04-0 o-Anisidine, also known as 2-methoxyaniline, is an aromatic amine with the chemical formula C7H9NO. It is a colorless to yellowish liquid with a characteristic odor, used primarily as an intermediate in the synthesis of various dyes, pigments, and pharmaceuticals. 1.\u00a0Chemical Properties IUPAC Name: [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>o-Anisidine (2-Methoxyaniline): Chemical Properties, Synthesis, Applications, and Safety Considerations - China Chemical Manufacturer<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangextracts.com\/da\/o-anisidin-2-methoxyanilin-kemiske-egenskaber-syntese-anvendelser-og-sikkerhedsovervejelser\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"o-Anisidine (2-Methoxyaniline): Chemical Properties, Synthesis, Applications, and Safety Considerations - China Chemical Manufacturer\" \/>\n<meta property=\"og:description\" content=\"o-Anisidine (2-Methoxyaniline): Chemical Properties, Synthesis, Applications, and Safety Considerations o-Anisidine CAS 90-04-0 o-Anisidine, also known as 2-methoxyaniline, is an aromatic amine with the chemical formula C7H9NO. 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