{"id":10625,"date":"2026-03-09T05:16:39","date_gmt":"2026-03-09T05:16:39","guid":{"rendered":"https:\/\/longchangextracts.com\/d-2-aminoadipic-acid-cas-7620-28-2-a-comprehensive-guide-to-this-metabolic-health-compound\/"},"modified":"2026-03-09T05:16:39","modified_gmt":"2026-03-09T05:16:39","slug":"d-2-aminoadipic-acid-cas-7620-28-2-a-comprehensive-guide-to-this-metabolic-health-compound","status":"publish","type":"post","link":"https:\/\/longchangextracts.com\/da\/d-2-aminoadipic-acid-cas-7620-28-2-a-comprehensive-guide-to-this-metabolic-health-compound\/","title":{"rendered":"D-2-Aminoadipic Acid (CAS 7620-28-2): A Comprehensive Guide to This Metabolic Health Compound"},"content":{"rendered":"

D-2-Aminoadipic Acid (CAS 7620-28-2): A Comprehensive Guide to This Metabolic Health Compound<\/h1>\n

What is D-2-Aminoadipic Acid?<\/h2>\n

D-2-Aminoadipic acid<\/strong> (CAS 7620-28-2) is a naturally occurring amino acid derivative that serves as a crucial intermediate in lysine metabolism<\/strong>. This compound, also known as 2-aminoadipic acid or 2-AAA, has garnered significant attention in recent years due to its emerging role in metabolic health and disease prevention.<\/p>\n

Chemically, D-2-aminoadipic acid is a dicarboxylic acid with the molecular formula C\u2086H\u2081\u2081NO\u2084. It is classified as a non-proteinogenic amino acid, meaning it is not incorporated into proteins but plays vital roles in various metabolic pathways.<\/p>\n

What Are the Benefits?<\/h2>\n

Blood Sugar Regulation<\/h3>\n

One of the most promising benefits of D-2-aminoadipic acid is its ability to lower fasting plasma glucose levels<\/strong>. Research published in the Journal of Clinical Investigation demonstrated that administration of 2-AAA effectively reduced blood glucose levels in mice fed both standard chow and high-fat diets [1].<\/p>\n

Enhanced Insulin Secretion<\/h3>\n

Studies have shown that 2-AAA treatment enhances insulin secretion<\/strong> from pancreatic \u03b2-cells. This includes effects on murine and human islets, making it a promising compound for diabetes management [2].<\/p>\n

Lipid Metabolism Improvement<\/h3>\n

Research indicates that 2-AAA plays a crucial role in regulating glycolipid metabolism<\/strong> independent of diet and exercise. This metabolic regulation includes promoting lipogenesis and fatty acid oxidation, leading to improved lipid profiles [3].<\/p>\n

Insulin Sensitivity Enhancement<\/h3>\n

Supplementation with 2-AAA has been associated with improved insulin sensitivity<\/strong>, lower blood glucose levels, and better overall metabolic function. These effects make it a potential therapeutic agent for metabolic disorders [4].<\/p>\n

Potential Anti-Aging Properties<\/h3>\n

Elevated levels of 2-AAA have been associated with aging and certain pathological conditions, but research suggests that modulating this metabolite may offer anti-aging benefits through improved metabolic function.<\/p>\n

What Are the Uses?<\/h2>\n

Dietary Supplement Ingredient<\/h3>\n

D-2-aminoadipic acid is increasingly being used as a dietary supplement ingredient<\/strong> for metabolic health support. Its ability to influence glucose metabolism makes it attractive for formulations targeting blood sugar management.<\/p>\n

Nutraceutical Formulations<\/h3>\n

The compound is incorporated into various nutraceutical products<\/strong> designed to support overall metabolic wellness, particularly for individuals with prediabetes or metabolic syndrome.<\/p>\n

Research and Development<\/h3>\n

2-AAA continues to be a subject of extensive medical research<\/strong>, particularly in understanding the mechanisms of metabolic diseases and developing novel therapeutic interventions.<\/p>\n

Biomarker Applications<\/h3>\n

D-2-aminoadipic acid serves as a biomarker<\/strong> for assessing diabetes risk and metabolic health status. Elevated fasting concentrations have been strongly associated with future diabetes development.<\/p>\n

Safety and Side Effects<\/h2>\n

Current research on D-2-aminoadipic acid supplementation shows promising safety profiles in experimental models. However, as with any bioactive compound:<\/p>\n