Alpha Lipoic Acid (CAS 1077-28-7): Comprehensive Guide to the Universal Antioxidant

Alpha Lipoic Acid (ALA), also known as Thioctic Acid, is a naturally occurring compound that serves as a powerful antioxidant in the human body. With the CAS number 1077-28-7 and molecular formula C8H14O2S2, this versatile compound has gained significant attention in the health and supplement industries. This comprehensive guide explores the science, benefits, applications, and sourcing of Alpha Lipoic Acid for manufacturers and healthcare professionals.

What is Alpha Lipoic Acid?

Alpha Lipoic Acid is a fatty acid found naturally in every cell of the human body. It plays a crucial role in mitochondrial cellular energy production and serves as a potent antioxidant that helps protect cells from oxidative damage. What makes ALA unique among antioxidants is its ability to function in both water-soluble and fat-soluble environments, allowing it to penetrate all parts of the cell.

Chemical Properties

• CAS Number: 1077-28-7
• Molecular Formula: C8H14O2S2
• Molecular Weight: 206.33 g/mol
• Synonyms: ALA, Thioctic Acid, Lipoic Acid, 6,8-Dithiooctanoic acid
• Physical Form: Yellow crystalline powder
• Solubility: Soluble in both water and organic solvents

Health Benefits and Scientific Evidence

1. Antioxidant Protection

Alpha Lipoic Acid works as a powerful antioxidant by neutralizing free radicals and regenerating other essential antioxidants, including Vitamin C, Vitamin E, and Glutathione.

2. Blood Sugar Management

Clinical studies have demonstrated that ALA can help improve insulin sensitivity and lower blood glucose levels.

3. Nerve Health Support

One of the most well-documented benefits of Alpha Lipoic Acid is its ability to support nerve health.

4. Anti-Aging Potential

As an antioxidant that can cross the blood-brain barrier and regenerate cellular energy, ALA has been studied for its potential anti-aging effects.

5. Cardiovascular Support

Research suggests that ALA may benefit heart health by reducing oxidative stress.

Applications in Dietary Supplements

Alpha Lipoic Acid is widely used in various supplement formulations: Single-ingredient supplements, Anti-aging formulas, Blood sugar support blends, Energy and vitality products, Neuroprotective formulations.

Recommended Dosage

Typical dosages in clinical studies range from 300-600 mg daily.

Safety and Side Effects

Alpha Lipoic Acid is generally well-tolerated when used at recommended doses.

Bulk Sourcing and Manufacturing

For manufacturers seeking to incorporate Alpha Lipoic Acid into their supplement formulations, sourcing high-quality bulk powder is essential.

Conclusion

Alpha Lipoic Acid represents one of the most versatile and scientifically supported antioxidants available today.