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Moxidectin CAS 113507-06-5

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CAS number
113507-06-5
Chemical name
Moxidectin
Molecular formula
113507-06-5
Molecular weight
639.825

Technical information

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Item Specifications Results
Appearance White or pale yellow amorphous powder White amorphous powder
Identification IR spectrum of sample corresponds to that of reference substance Comply
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay Comply
Water ≤1.3 % 0.6 %
Residue on ignition ≤0.2 % 0.04 %
Heavy Metals ≤20 ppm < 20 ppm
Assay( anhydrous basis ) 92.0 % – 102.0 % 98.2 %
Organic impurities Early-eluting impurities Moxidectin butenyl analog ( A ) ≤1.5 % 0.1 %
5’-Demethyl moxidectin( B ) ≤0.5% 0.2 %
Moxidectin pentenly analog ( C ) ≤1.5 % 0.4 %
Moxidectin 17a-epimer ( D ) ≤2.5% 0.2 %
Sum of moxidectin 19-S-17a-ene and moxidectin ethyl isomers (E F ) ≤1.7 % 0.3 %
Milbemycin B analog ( moxidectin open ring ) \( G ) ≤1.5 % Not detected
Any other individual impurity eluting before milbemycin B analog ( moxidectin open ring ) ≤0.5 % 0.2 %
Late-eluting impurities Moxidectin deoxydienea and 4’-Methylthiomethoxymoxidectin ( H I ) ≤1.0 % Not detected
20b-Methylthiomoxidectin( J ) ≤0.5 % Not detected
20-Nitrobenzoylmoxidectin( K ) ≤0.5 % Not detected
Any other individual impurity eluting after the milbemycin B analog (moxidectin open ring ) ≤0.5 % Not detected
Total organic impurities ≤7.0 % 1.7 %
Solvent residue Methanol ≤3000 ppm Not detected
Methylene chloride ≤300 ppm Not detected
Isopropyl acetate ≤5000 ppm Not detected
N-heptane ≤3000 ppm 72 ppm
BHT 0.3 % – 0.6 % 0.49 %
Conclusion The product complies with the specification ( USP )
Storage Preserve in well-closed, light-resistant containers, and store in room temperature .

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