quinine sulfate dihydrate cas 6119-70-6

Chemical Name: Quinine sulfate dihydrate

CAS No.: 6119-70-6

Molecular Formula: C40H48N4O4·H2SO4·2H2O

Chemical Structure:

Molecular weight:782.96

Appearance: White or almost white, crystalline powder or fine, colourless needles

Assay: 99.0-101.0

Quinine sulfate dihydratetypical Properties

Item	Specifications
Appearance	White or almost white, crystalline powder or fine, colourless needles
Solubility	Slightly soluble in water sparingly souluble in boiling water and in ethanol
PH	5.7-6.6
Specific optical rotation	-237- -245
Other cinchona alkaloids	ImpurityC ≤10%Any impurity eluted before quinine≤5.0%Anyotherimpurity≤2.5%
Loss on drying	3.0%-5.0%
Suiphated ash	≤0.1%
Assay	99.0-101.0

Quinine sulfate dihydrateUsage

Quinine sulfate is a quinoline derivative that binds to the DNA of Plasmodium and forms a complex that inhibits DNA replication and RNA transcription, thereby inhibiting protozoal protein synthesis, which is weaker than chloroquine. It is suitable for falciparum malaria caused by chloroquine and multi-drug resistant strains. It can also be used to treat vivax malaria. For asthma, atrial fibrillation and other serious heart conditions, patients with glucose-6-phosphate dehydrogenase deficiency and women’s menstrual period should be used with caution. Pregnant women are banned.

Quinine sulfate dihydratePackaging and Shipping

Packing: 25kg/drum

Delivery: have the stock

5-Acetyl-2,4-dimethylthiazoleStorage

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

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